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http://www.blogtalkradio.com/facesoftbi/2018/02/22/regenerative-medicine-for-repair-remodeling-of-the-damaged-cns-w-ira-pastor

The study of consciousness and what makes us individuals is a topic filled with complexities. From a neuroscience perspective, consciousness is derived from a self-model as a unitary structure that shapes our perceptions, decisions and feelings. There is a tendency to jump to the conclusion with this model that mankind is being defined as self-absorbed and only being in it for ourselves in this life. Although that may be partially true, this definition of consciousness doesn’t necessarily address the role of morals and how that is shaped into our being. In the latest addition to The Galactic Public Archives, Dr. Ken Hayworth tackles the philosophical impact that technologies have on our lives.

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Posthumanists and perhaps especially transhumanists tend to downplay the value conflicts that are likely to emerge in the wake of a rapidly changing technoscientific landscape. What follows are six questions and scenarios that are designed to focus thinking by drawing together several tendencies that are not normally related to each other but which nevertheless provide the basis for future value conflicts.

  1. Will ecological thinking eventuate in an instrumentalization of life? Generally speaking, biology – especially when a nervous system is involved — is more energy efficient when it comes to storing, accessing and processing information than even the best silicon-based computers. While we still don’t quite know why this is the case, we are nevertheless acquiring greater powers of ‘informing’ biological processes through strategic interventions, ranging from correcting ‘genetic errors’ to growing purpose-made organs, including neurons, from stem-cells. In that case, might we not ‘grow’ some organs to function in largely the same capacity as silicon-based computers – especially if it helps to reduce the overall burden that human activity places on the planet? (E.g. the brains in the vats in the film The Minority Report which engage in the precognition of crime.) In other words, this new ‘instrumentalization of life’ may be the most environmentally friendly way to prolong our own survival. But is this a good enough reason? Would these specially created organic thought-beings require legal protection or even rights? The environmental movement has been, generally speaking, against the multiplication of artificial life forms (e.g. the controversies surrounding genetically modified organisms), but in this scenario these life forms would potentially provide a means to achieve ecologically friendly goals.

  1. Will concerns for social justice force us to enhance animals? We are becoming more capable of recognizing and decoding animal thoughts and feelings, a fact which has helped to bolster those concerned with animal welfare, not to mention ‘animal rights’. At the same time, we are also developing prosthetic devices (of the sort already worn by Steven Hawking) which can enhance the powers of disabled humans so their thoughts and feelings are can be communicated to a wider audience and hence enable them to participate in society more effectively. Might we not wish to apply similar prosthetics to animals – and perhaps even ourselves — in order to facilitate the transaction of thoughts and feelings between humans and animals? This proposal might aim ultimately to secure some mutually agreeable ‘social contract’, whereby animals are incorporated more explicitly in the human life-world — not as merely wards but as something closer to citizens. (See, e.g., Donaldson and Kymlicka’s Zoopolis.) However, would this set of policy initiatives constitute a violation of the animals’ species integrity and simply be a more insidious form of human domination?

  1. Will human longevity stifle the prospects for social renewal? For the past 150 years, medicine has been preoccupied with the defeat of death, starting from reducing infant mortality to extending the human lifespan indefinitely. However, we also see that as people live longer, healthier lives, they also tend to have fewer children. This has already created a pensions crisis in welfare states, in which the diminishing ranks of the next generation work to sustain people who live long beyond the retirement age. How do we prevent this impending intergenerational conflict? Moreover, precisely because each successive generation enters the world without the burden of the previous generations’ memories, it is better disposed to strike in new directions. All told then, then, should death become discretionary in the future, with a positive revaluation of suicide and euthanasia? Moreover, should people be incentivized to have children as part of a societal innovation strategy?

  1. Will the end of death trivialize life? A set of trends taken together call into question the finality of death, which is significant because strong normative attitudes against murder and extinction are due largely to the putative irreversibility of these states. Indeed, some have argued that the sanctity – if not the very meaning — of human life itself is intimately related to the finality of death. However, there is a concerted effort to change all this – including cryonics, digital emulations of the brain, DNA-driven ‘de-extinction’ of past species, etc. Should these technologies be allowed to flourish, in effect, to ‘resurrect’ the deceased? As it happens, ‘rights of the dead’ are not recognized in human rights legislation and environmentalists generally oppose introducing new species to the ecology, which would seem to include not only brand new organisms but also those which once roamed the earth.

  1. Will political systems be capable of delivering on visions of future human income? There are two general visions of how humans will earn their keep in the future, especially in light of what is projected to be mass technologically induced unemployment, which will include many ordinary professional jobs. One would be to provide humans with a ‘universal basic income’ funded by some tax on the producers of labour redundancy in both the industrial and the professional classes. The other vision is that people would be provided regular ‘micropayments’ based on the information they routinely provide over the internet, which is becoming the universal interface for human expression. The first vision cuts against the general ‘lower tax’ and ‘anti-redistributive’ mindset of the post-Cold War era, whereas the latter vision cuts against perceived public preference for the maintenance of privacy in the face of government surveillance. In effect, both visions of future human income demand that the state reinvents its modern role as guarantor of, respectively, welfare and security – yet now against the backdrop of rapid technological change and laissez faire cultural tendencies.

  1. Will greater information access turn ‘poverty’ into a lifestyle prejudice? Mobile phone penetration is greater in some impoverished parts of Africa and Asia than in the United States and some other developed countries. While this has made the developed world more informationally available to the developing world, the impact of this technology on the latter’s living conditions has been decidedly mixed. Meanwhile as we come to a greater understanding of the physiology of impoverished people, we realize that their nervous systems are well adapted to conditions of extreme stress, as are their cultures more generally. (See e.g. Banerjee and Duflo’s Poor Economics.) In that case, there may come a point when the rationale for ‘development aid’ might disappear, and ‘poverty’ itself may be seen as a prejudicial term. Of course, the developing world may continue to require external assistance in dealing with wars and other (by their standards) extreme conditions, just as any other society might. But otherwise, we might decide in an anti-paternalistic spirit that they should be seen as sufficiently knowledgeable of their own interests to be able to lead what people in the developed world might generally regard as a suboptimal existence – one in which, say, the life expectancies between those in the developing and developed worlds remain significant and quite possibly increase over time.

Fox 29 — Good Day Philadelphia

http://www.fox29.com/140735577-video

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NBC TV 10

http://www.nbcphiladelphia.com/news/local/Zombies-from-Philly_-Local-Firm-Hopes-to-Bring-People-Back-from-the-Dead_Philadelphia-378365101.html

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CNN en Espanol

http://cnnespanol.cnn.com/video/cnnee-encuentro-intvw-joel-osorio-bioquantina-muerte-cerebral/

Researcher-test

Bioquark, Inc., (http://www.bioquark.com) a company focused on the development of novel biologics for complex regeneration and disease reversion, and Revita Life Sciences, (http://revitalife.co.in) a biotechnology company focused on translational therapeutic applications of autologous stem cells, have announced that they have received IRB approval for a study focusing on a novel combinatorial approach to clinical intervention in the state of brain death in humans.

This first trial, within the portfolio of Bioquark’s Reanima Project (http://www.reanima.tech) is entitled “Non-randomized, Open-labeled, Interventional, Single Group, Proof of Concept Study With Multi-modality Approach in Cases of Brain Death Due to Traumatic Brain Injury Having Diffuse Axonal Injury” (https://clinicaltrials.gov/ct2/show/NCT02742857?term=bioquark&rank=1), will enroll an initial 20 subjects, and be conducted at Anupam Hospital in Rudrapur, Uttarakhand India.

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“We are very excited about the approval of our protocol,” said Ira S. Pastor, CEO, Bioquark Inc. “With the convergence of the disciplines of regenerative biology, cognitive neuroscience, and clinical resuscitation, we are poised to delve into an area of scientific understanding previously inaccessible with existing technologies.”

Death is defined as the termination of all biological functions that sustain a living organism. Brain death, the complete and irreversible loss of brain function (including involuntary activity necessary to sustain life) as defined in the 1968 report of the Ad Hoc Committee of the Harvard Medical School, is the legal definition of human death in most countries around the world. Either directly through trauma, or indirectly through secondary disease indications, brain death is the final pathological state that over 60 million people globally transfer through each year.

While human beings lack substantial regenerative capabilities in the CNS, many non-human species, such as amphibians, planarians, and certain fish, can repair, regenerate and remodel substantial portions of their brain and brain stem even after critical life-threatening trauma.

operation

Additionally, recent studies on complex brain regeneration in these organisms, have highlighted unique findings in relation to the storage of memories following destruction of the entire brain, which may have wide ranging implications for our understanding of consciousness and the stability of memory persistence.

“Through our study, we will gain unique insights into the state of human brain death, which will have important connections to future therapeutic development for other severe disorders of consciousness, such as coma, and the vegetative and minimally conscious states, as well as a range of degenerative CNS conditions, including Alzheimer’s and Parkinson’s disease,” said Dr. Sergei Paylian, Founder, President, and Chief Science Officer of Bioquark Inc.

Over the years, clinical science has focused heavily on preventing such life and death transitions and made some initial progress with suspended animation technologies, such as therapeutic hypothermia. However, once humans transition through the brain death window, currently defined by the medical establishment as “irreversible”, they are technically no longer alive, despite the fact that human bodies can still circulate blood, digest food, excrete waste, balance hormones, grow, sexually mature, heal wounds, spike a fever, and gestate and deliver a baby. It is even acknowledged by thought leaders that recently brain dead humans still may have residual blood flow and electrical nests of activity in their brains, just not enough to allow for an integrated functioning of the organism as a whole.

coolbrain

“We look forward to working closely with Bioquark Inc. on this cutting edge clinical initiative,” said Dr. Himanshu Bansal, Managing Director of Revita Life Sciences.

About Bioquark, Inc.

Bioquark Inc. is focused on the development of natural biologic based products, services, and technologies, with the goal of curing a wide range of diseases, as well as effecting complex regeneration. Bioquark is developing both biological pharmaceutical candidates, as well as products for the global consumer health and wellness market segments.

About Revita Life Sciences

Revita Life Sciences is a biotechnology company focused on the development of stem cell therapies that target areas of significant unmet medical need. Revita is led by Dr. Himanshu Bansal MD, PhD. who has spent over two decades developing novel MRI based classifications of spinal cord injuries as well as comprehensive treatment protocols with autologous tissues including bone marrow stem cells, dural nerve grafts, nasal olfactory tissues, and omental transposition.

“He is not here; He has risen,” — Matthew 28:6

As billions of Christians around the world are getting ready to celebrate the Easter festival and holiday, we take pause to appreciate the awe inspiring phenomena of resurrection.

crypt

In religious and mythological contexts, in both Western and Eastern societies, well known and less common names appear, such as Attis, Dionysus, Ganesha, Krishna, Lemminkainen, Odin, Osiris, Persephone, Quetzalcoatl, and Tammuz, all of whom were reborn again in the spark of the divine.

In the natural world, other names emerge, which are more ancient and less familiar, but equally fascinating, such as Deinococcus radiodurans, Turritopsis nutricula, and Milnesium tardigradum, all of whose abilities to rise from the ashes of death, or turn back time to start life again, are only beginning to be fully appreciated by the scientific world.

deinoccous

In the current era, from an information technology centric angle, proponents of a technological singularity and transhumanism, are placing bets on artificial intelligence, virtual reality, wearable devices, and other non-biological methods to create a future connecting humans to the digital world.

This Silicon Valley, “electronic resurrection” model has caused extensive deliberation, and various factions to form, from those minds that feel we should slow down and understand the deeper implications of a post-biologic state (Elon Musk, Steven Hawking, Bill Gates, the Vatican), to those that are steaming full speed ahead (Ray Kurzweil / Google) betting that humans will shortly be able to “transcend the limitations of biology”.

transhumangirl

However, deferring an in-depth Skynet / Matrix discussion for now, is this debate clouding other possibilities that we have forgotten about, or may not have even yet fully considered?

Today, we find ourselves at an interesting point in history where the disciplines of regenerative sciences, evolutionary medicine, and complex systems biology, are converging to give us an understanding of the cycle of life and death, orders of magnitude more complex than only a few years ago.

In addition to the aforementioned species that are capable of biologic reanimation and turning back time, we show no less respect for those who possess other superhuman capabilities, such as magnetoreception, electrosensing, infrared imaging, and ultrasound detection, all of which nature has been optimizing over hundreds of millions of years, and which provide important clues to the untapped possibilities that currently exist in direct biological interfaces with the physical fabric of the universe.

jellyfish2

The biologic information processing occurring in related aneural organisms and multicellular colony aggregators, is no less fascinating, and potentially challenges the notion of the brain as the sole repository of long-term encoded information.

Additionally, studies on memory following the destruction all, or significant parts of the brain, in regenerative organisms such as planarians, amphibians, metamorphic insects, and small hibernating mammals, have wide ranging implications for our understanding of consciousness, as well as to the centuries long debate between the materialists and dualists, as to whether we should focus our attention “in here”, or “out there”.

I am not opposed to studying either path, but I feel that we have the potential to learn a lot more about the topic of “out there” in the very near future.

coolbrain

The study of brain death in human beings, and the application of novel tools for neuro-regeneration and neuro-reanimation, for the first time offer us amazing opportunities to start from a clean slate, and answer questions that have long remained unanswered, as well as uncover a knowledge set previously thought unreachable.

Aside from a myriad of applications towards the range of degenerative CNS indications, as well as disorders of consciousness, such work will allow us to open a new chapter related to many other esoteric topics that have baffled the scientific community for years, and fallen into the realm of obscure curiosities.

connection

From the well documented phenomena of terminal lucidity in end stage Alzheimer’s patients, to the mysteries of induced savant syndrome, to more arcane topics, such as the thousands of cases of children who claim to remember previous lives, by studying death, and subsequently the “biotechnological resurrection” of life, we can for the first time peak through the window, and offer a whole new knowledge base related to our place, and our interaction, with the very structure of reality.

We are entering a very exciting era of discovery and exploration.

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About the author

Ira S. Pastor is the Chief Executive Officer of Bioquark Inc. (www.bioquark.com), an innovative life sciences company focusing on developing novel biologic solutions for human regeneration, repair, and rejuvenation. He is also on the board of the Reanima Project (www.reanima.tech)

I have spent the last 30 years in various aspects of the biopharmaceutical industry, which for the most part has been a very rewarding experience.

However, during this time period, having been immersed many different components of therapeutic development and commercialization, one thing has always bothered me: a wide array of promising research never makes it off the bench to see the translational light of day, and gets lost in the historical scientific archives.

bqiinclab

I always believed that scientific progress happened in a very linear narrative, with each new discovery supporting the next, resulting ultimately in an eventual stairway of scientific enlightenment.

What the reality turned out to be was much more of a fragmented, research “evolutionary tree”, with dozens of potential pathways, only very few branches of which ever resulted in scientific maturity, and not always the most fruitful ones by any means.

The premature extinction of these promising discovery pathways were the result of a variety of factors, including, but not limited to, funding priorities, competing industrial interests, “out of vogue” concepts, lack of intellectual properties, non-existent regulatory models, conflicted legislative initiatives, and even religious implications.

In 2016, as in previous years, we continue to see these “valleys of death” swallow up pathways of scientific possibility, with few popular segments attracting the majority of attention and support.

gene sequencing

The preponderance of resources focused on the somatic mutation model of carcinogenesis, despite an endless range of research highlighting that the disease is extremely heterogenic and rarely ever follows such a clonal model, is one example that continues to be inappropriately manifested in the oncology system, decades into the “war on cancer”.

On a similar plane, the jettisoning of most studies of the biophysical aspects of human genetics, despite the gross incompleteness offered by the central dogma to explain higher biological form and function, is another example that has become all too pervasive in the research community.

And then there are the areas of human consciousness, memory, and information processing / storage, where in many ways we are still operating in the dark ages, with materialists and dualists battling it out for centuries.

One topic that I have written quite a bit about is that of death, specifically that of the death of the human brain — http://www.singularityweblog.com/is-death-reversible/

brainimage

While I am a staunch supporter and advocate of the life-extension / anti-aging movement, I am equally vocal about our need to develop technologies, products, and services that can actually reverse our ultimate transition between the living and dead states, a transition that occurs annually for 60 million humans around the globe.

Death, however, is unfortunately seen by many as a natural, biological progression for human beings, and in many circles, deemed an unnecessary area of scientific research and exploration.

I beg to differ.

Far too often, death arrives too early and too unexpectedly for many of us and our loved ones. And the best modern medicine has to offer today is “Sorry. There is nothing else we can do.”

But what if there was?

There are a variety of species across the natural world that are capable of regenerating and repairing themselves from forms of severe CNS damage that bring them to the transitional grey zone between life and death. Along the evolutionary timeline however, this ability gradually disappeared hundreds of millions of years ago and does not manifest in higher species.

lizard and lady

Now, in the 21st century, with the convergence of the disciplines of regenerative biology, cognitive neuroscience, and clinical resuscitation, we may finally be poised to take back these capabilities for humans.

Over the years, clinical science has focused heavily on preventing such life and death transitions and made some initial progress with suspended animation technologies, such as therapeutic hypothermia. But once we transition through the brain death window, currently defined by the medical establishment as “irreversible” (per the 1968 Ad Hoc Committee of the Harvard Medical School definition), we are technically no longer alive.

surgeons

To add insult to injury, a human can be declared dead, even while our bodies can still circulate blood, digest food, excrete waste, balance hormones, grow, sexually mature, heal wounds, spike a fever, and gestate and deliver a baby. It is even acknowledged by thought leaders that recently brain dead humans still may have residual blood flow and electrical nests of activity in their brains, just not enough to allow for an integrated functioning of the organism as a whole.

Several prominent cases in the media over the past few years have further served to highlight the current situation, as well as the substantial anatomical and functional differences between the state known as brain death, and other severe disorders of consciousness, such as coma, and the vegetative and minimally conscious states.

It is now time to take the necessary steps to provide new possibilities of hope, in order to counter the pain, sorrow, and grief that is all too pervasive in the world when we experience a loved one’s unexpected or untimely death, due to lesions which might be potentially reversible with the application of promising neuro-regeneration and neuro-reanimation technologies and therapies.

bqaproduction

It is time to undertake the required research, based on 2016 technological knowledge, in order to bring about such transformational change.

My name is Ira S. Pastor and I am the CEO of the biotechnology company Bioquark Inc.

Welcome to the unveiling of the Reanima project.

Reanima Video

Controlling the brain, consciousness and the unconscious through artificial means has long been a staple plot of science fiction. Yet history has a way of proving the fictional to end up as possible, and the future of brain-machine interface appears to hold greater promise than ever before.

Image Credit: Society for Neuroscience (SFN)
Image Credit: Society for Neuroscience (SFN)

According to Neuroscience Researcher, Yale University Fellow, and the Director of Yale’s Clinical Neuroscience Imaging Center, Dr. Hal Blumenfeld, we can now therapeutically (and safely) go inside the brain. As he reflected on the recent advances in neuroscience, Blumenfeld cited the progress that’s been made in the last decade in understanding the relationship between brain activity and conscious thought as one of the biggest breakthroughs. The ability to find the switch in the brain that regulates consciousness, and turn it on and off, is a major step toward the treatment of epilepsy, brain injuries and more, and could have a profound effect on mankind, he said.

“I think the exciting advances are really looking in the network approach to understanding the brain, looking at the brain as a network, and understanding that, for something as wide reaching as consciousness to happen, you really need the whole brain network or most of the brain,” Blumenfeld said. “There’s a switch deep in the middle of the brain that can either be turned on or off. When that gets turned on, the whole rest of the brain network, including the cortex, all start to interact and create consciousness. When that switch gets flipped off, consciousness is turned down and we lose consciousness.”

While it sounds like a simple on/off operation, Blumenfeld noted that it’s not a smooth, linear process and that the different states of consciousness are subject to big jumps and rapid changes in the transition. Where researchers have made the biggest leaps, he said, is in gaining an understanding of those transitions and interactions throughout the entire network of the brain and how they regulate the level of arousal, attention and awareness.

Going forward, these breakthroughs could have a major effect in managing epileptic seizures, Blumenfeld said. While an epileptic seizure usually only affects one part of the brain, the seizure itself also flips that consciousness on/off switch to off. Avoiding that loss of consciousness during a seizure, he said, can also make the effects of the seizure milder and by extension, help improve the quality of life for those who suffer from epilepsy.

“The technology for deep brain stimulation has progressed fantastically in recent years, and it’s already being done for movement disorders, epilepsy and for chronic pain. (We have the technology to) safely implant in people’s brains a stimulator, like a pacemaker or a defibrillator, that detects when a seizure is happening and starts a stimulus,” Blumenfeld said. “Medicines and deep brain stimulation are not going to cure everyone of their seizures but, what this tells us is, there is another whole strategy we can take. Even if we can’t stop the seizures, if we can flip that switch back on so people will regain their consciousness during and after the seizure, they’ll be much better off.”

Beyond epilepsy, these new approaches in treatment can also be applied to those in a coma, those in a chronic vegetative state, and other disorders of consciousness, Blumenfeld said. These aren’t the only maladies being researched for brain stimulation. The use of optogenetics is also currently being studied for use in therapy and other brain disorders, he added. Ed Boyden and the Synthetic Neurobiology Group at MIT are hard at work in this domain of research.

“I think optogenetics is tremendously exciting and will continue to grow. There are a lot of challenges to implementing it in humans and safely carrying it out, but the promise is there,” Blumenfeld said. “It has a much more selective mode of action with individual neurons and I believe that eventually, we’ll be able to use that too (in our research). It will just take a bit more time until we get to that point.”

Looking forward, Blumenfeld noted that the potential future applications of BMI and brain stimulation could one day expand to attention disorders and even the modulation of human emotion. However, owing to the ethical questions that will certainly arise, he feels a priority should remain on developing further treatments or therapies for those who need it the most.

“First and foremost, we’ve got to look at the benefits we’re talking about, for people who are really suffering and really have tremendously impacted quality of life because of unpredictable-at-any-time-losing consciousness due to seizure, not being able to drive or, worse, people who are in a vegetative state. I think these are very promising therapies,” Blumenfeld said. “While scientists and human beings always have to consider the implications of them being used inappropriately, I think that doesn’t diminish from the importance of moving forward and developing these treatments so that they can be used for the people who need them the most.”

Progress always seems to ride a slippery slope. Innovations generally bring a plethora of potential benefits and just as many dangers, the obvious and the hidden. Technologies that tamper with our biological constructs is well underway in the neuro- and biotech industries. Historically, innovations in medicine have usually been beneficial on the aggregate.

But these new breakthroughs go beyond preventing and healing pre-existing causes. Transhuman technologies hold the promise of enhancing who we are as individuals and potentially as an entire species, and the decisions surrounding these technologies are far from simple. Dr. Nayef Al-Rodhan, a philosopher, neuroscientist, and director of the Geneva Center for Security Policy, believes we should be acting now to prepare for the inevitable and the unpredictable ramifications.

Framing Human Motivation

Considering our mixed track record as a species in rolling out groundbreaking innovations, discussing and finding potential solutions to many of the hidden dangers, and obvious ones, seems more than reasonable. One of the more puzzling questions is, where do we begin to have a pragmatic conversation on the ethics of these technologies?

There are plenty of theories about what drive human decisions, not least because human morality is infinitely complex and our minds crave frames through which to make sense of chaos. Dr. Al-Rodhan has his own conception of what drives human motivations. He makes meaning using the lens of “5 P’s” – Power, Pride, Profit, Pleasure, and Permanence – which he posits drive human motivations. “This is my view, the foundation of my outlook…this perceived emotion of self interest drives our moral compass.”

Al-Rodhan’s view of human nature seems to make a lot of sense, bridging the rational with the emotional. Such a frame is particularly helpful when considering technology that undoubtedly taps into our deepest fears and hopes, and invokes rational (and irrational) debate. During a recent TechEmergence interview with Nayef, I asked for his thoughts on the concerns and considerations of this brand of technology in the coming decade.

The Near Business of Enhancement

Al-Rodhan believes that we will see cognitive enhancement primarily through neuropharmacology, or neuro- and psychostimulants. This concept of this technology is nothing new — the military and many other organization have used their stimulants of choice in the past, one of the most pervasive being alcohol. But this new wave of neuro- and psychostimulants will methodically target specific areas in the brain, giving way to the possibility for innovations like increased mood modulation and more cognitive ability within the confines of the brain’s neuronal population.

Neuromodulation has been used in the military, with some efforts to make soldiers less emotional and to require less sleep. The difficulties with side effects are often more pronounced when soldiers return from combat. “They are all messed up due to severe brutality, fear, and some of these agents they are given make them addicts to certain things,” says Nayef, acknowledging that this happens in most all militaries. “The point is that psychostimulants and neuromodulators will make us feel very good, but they are very dangerous because they require addictive behavior…and we need strict oversight mechanisms.”

Nayef says that technologies such as brain machine interface (BMI) are likely beyond the span of a decade, but that implantable microchips (whether bio or biotechnological) are as much of an immediate concern as the introduction of neurostimulants. “The FDA in the United States is entrusted with keeping us on the right path,” says Al-Rodhan.

Finding Common Regulatory Ground

Is it possible to put in place national or international structures for managing these new and emerging technologies? Al-Rodhan believes it is more than possible; however, the primary issue is that our regulation is way behind innovation. Regulatory frameworks are lacking for a number of reasons. The unpopularity in politics is a major obstacle to overcome. In elections, these types of contradictory frameworks are not politically on the front burner for most candidates, and the long-term outlook is limited.

Another area for concern is corporate pharmaceutical entities, which Nayef says are not as well regulated as some might think. Businesses are concerned about the bottom line above all else, which at times yields unfortunate outcomes for the whole of society. “This is part of their role as executive, they’re not too concerned about moral regulation,” says Nayef. As unappealing as it might sound to free market capitalists, the institution that traditionally steps into these frontiers to regulate is government.

A relevant and current example is the science and business of moderating genomes in China, which is already investing a lot of money in this industry. Some effects of this technology may not be so obvious at first, and it is possible that negative ramifications could occur without the correct bioethical oversight. Al-Rodhan asks “what happens if you get a piece of DNA that preludes the biosphere? Who knows what kind of mutation that may produce spontaneously or by merging with other DNA in an organism.” These are the types of questions that governments, academic institutions, corporations, and individual citizens need to be asking, considering the multiple perspectives that emerge from a framework like Al-Rodhan’s that applies across cultural boundaries.

Al-Rodhan describes the process of implementing such regulatory frameworks as a transnational effort, but says that such efforts start with countries like the U.S., Japan, and Europe, where accountable mechanisms already exist. Taking the lead doesn’t guarantee the same priorities will be given elsewhere, but it can provide an example — and ideally a positive one. “We have about a decade to get our act together,” says Al-Rodhan.

The study of consciousness and what makes us individuals is a topic filled with complexities. From a neuroscience perspective, consciousness is derived from a self-model as a unitary structure that shapes our perceptions, decisions and feelings. There is a tendency to jump to the conclusion with this model that mankind is being defined as self-absorbed and only being in it for ourselves in this life. Although that may be partially true, this definition of consciousness doesn’t necessarily address the role of morals and how that is shaped into our being. In the latest addition to The Galactic Public Archives, Dr. Ken Hayworth tackles the philosophical impact that technologies have on our lives.

Our previous two films feature Dr. Hayworth extrapolating about what radical new technologies in neuroscience could eventually produce. In a hypothetical world where mind upload is possible and we could create a perfect replica of ourselves, how would one personally identify? If this copy has the same memories and biological components, our method of understanding consciousness would inevitably shift. But when it comes down it, if we were put in a situation where it would be either you or the replica – it’s natural evolutionary instinct to want to save ourselves even if the other is an exact copy. This notion challenges the idea that our essence is defined by our life experiences because many different people can have identical experiences yet react differently.

Hayworth explains, that although there is an instinct for self-survival, humanity for the most part, has a basic understanding not to cause harm upon others. This is because morals are not being developed in the “hard drive” of your life experiences; instead our morals are tied to the very idea of someone just being a conscious and connected member of this world. Hayworth rationalizes that once we accept our flawed intuition of self, humanity will come to a spiritual understanding that the respect we give to others for simply possessing a reflection of the same kind of consciousness will be the key to us identifying our ultimate interconnectedness.

For now, the thought experiments featured in this third film remain firmly in the realm of science fiction. But as science fiction progresses closer to “science fact”, there is much to be considered about how our personal and societal values will inevitably shift — even if none of us needs to start worrying about where we’ve stored our back up memories just yet.

“If the doors of perception were cleansed, everything would appear to mankind as is, Infinite.”

-William Blake