Researchers from Zurich have developed a compact, energy-efficient device made from artificial neurons that is capable of decoding brainwaves. The chip uses data recorded from the brainwaves of epilepsy patients to identify which regions of the brain cause epileptic seizures. This opens up new perspectives for treatment.
Current neural network algorithms produce impressive results that help solve an incredible number of problems. However, the electronic devices used to run these algorithms still require too much processing power. These artificial intelligence (AI) systems simply cannot compete with an actual brain when it comes to processing sensory information or interactions with the environment in real time.
Many people who have been infected with SARS-CoV-2 will probably make antibodies against the virus for most of their lives. So suggest researchers who have identified long-lived antibody-producing cells in the bone marrow of people who have recovered from COVID-191.
The study provides evidence that immunity triggered by SARS-CoV-2 infection will be extraordinarily long-lasting. Adding to the good news, “the implications are that vaccines will have the same durable effect”, says Menno van Zelm, an immunologist at Monash University in Melbourne, Australia.
Antibodies — proteins that can recognize and help to inactivate viral particles — are a key immune defence. After a new infection, short-lived cells called plasmablasts are an early source of antibodies.
It’s the rare individual who actually looks forward to getting jabbed with a needle, even if what’s in the needle can protect them from a serious disease such as COVID-19.
But several teams around the world are working on a way to inject a vaccine without the ouch. The trick is to make the needles small. Really small. So small they don’t interact with the nerve endings that signal pain.
Mark Prausnitz is director of the Center for Drug Design, Development and Delivery at Georgia Tech. He works on something called microneedle patches to deliver vaccines. So far, he’s developed patch vaccines for flu and measles, but the technology could be used for a COVID-19 vaccine as well.
Benjamin Wallace-Wells writes about a growing consensus among researchers that the pathogen that gave rise to the COVID-19 pandemic may have emerged from a laboratory in Wuhan, China, rather than through a natural migration from animals to humans.
Things to note: Treating the rats until they die. They are at 31 months and the longest they have lived without treatments is 38 months. Also, a small number of people have done this and though ailments like arthritis go away they still look elderly.
We recently had an update from Professor Rodolfo Goya who is conducting a follow up experiment from the one that Dr. Katcher first did in India, showing a rejuvenation in old rats. This video goes through the update that we had and provides a short introduction to the background.
Nicolas Chernavsky recently also did an interview with Didier Coeurnelle which discussed the update, which you can find here : https://youtu.be/GMNXjvXV268
Our earlier videos on the previous experiment and interview with Dr. Katcher are in this playlist https://www.youtube.com/playlist?list=PLkfzM7KJv6vaIQZ_n3WS6FHTpBtfS2lzw.
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Rift Valley fever used to mostly affect livestock in Africa. But the virus that causes it is also spread by mosquitoes whose habitats are expanding because of climate change. If it were to make its way to the rest of the world, it would decimate livestock causing agricultural collapse as well as affecting human health.
In 2015 the Zika virus triggered a global health crisis that left thousands of parents devastated. The virus can cause serious problems in pregnancy, leading to babies with birth defects called microcephaly and other neurological problems. But Zika is not the only virus that can be devastating to pregnant women and their babies; there is another with pandemic potential that could be even more deadly – Rift Valley fever.
The placenta that encases the baby acts as a fortress against many pathogens, but a few can evade its defences. Rift Valley fever is one of them – a 2019 study shows that the virus has the ability to infect a specialised layer of placental cells that carry nutrients to the baby, something that even Zika may not be capable of. In cattle and other livestock, in which the virus spreads, infection can cause more than 90% of pregnant cows to miscarry or deliver stillborn calves. Although the virus kills fewer than 1% of people it infects, it is the risk to babies, and the lasting neurological effects in adults, that is of great concern.
Summary: Simple dietary changes and adopting lifestyle alterations, including improved sleep schedules, taking probiotics, and exercising, can reduce signs of biological aging by three years in just eight weeks, a new study reports.
Source: Impact Journals
A groundbreaking clinical trial shows we can reduce biological age (as measured by the Horvath 2013 DNAmAge clock) by more than three years in only eight weeks with diet and lifestyle through balancing DNA methylation.
A first-of-its-kind, peer-reviewed study provides scientific evidence that lifestyle and diet changes can deliver immediate and rapid reduction of our biological age. Since aging is the primary driver of chronic disease, this reduction has the power to help us live better, longer.
One hundred fifty years ago, Dmitri Mendeleev created the periodic table, a system for classifying atoms based on the properties of their nuclei. This week, a team of biologists studying the tree of life has unveiled a new classification system for cell nuclei and discovered a method for transmuting one type of cell nucleus into another.
The study, which appears this week in the journal Science, emerged from several once-separate efforts. One of these centered on the DNA Zoo, an international consortium spanning dozens of institutions including Baylor College of Medicine, the National Science Foundation-supported Center for Theoretical Biological Physics (CTBP) at Rice University, the University of Western Australia and SeaWorld.
Scientists on the DNA Zoo team had been working together to classify how chromosomes, which can be several meters long, fold up to fit inside the nuclei of different species from across the tree of life.
- Designed and led the TRIIM trial; Published the first report of thymus regeneration in a normal human; Granted patents on methods for and applications of human thymus regeneration. - Fellow of the American Aging Association. (since 2005), Former Director of the American Aging Association (16 years) - Editor-in-Chief, The Future of Aging: Pathways to Human Life Extension. - Awarded the Society for Cryobiology’s Luyet Medal in 2016. - In 2009, showed indefinite survival of rabbit kidney transplanted after cooling to-130°Celsius; Led 21CM team as co-winner of Small Mammal Brain Preservation Prize, 2018 winner of Large Mammal Brain Preservation Prize.
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Accumulated evidence from genetic animal models suggests that the brain, particularly the hypothalamus, has a key role in the homeostatic regulation of energy and glucose metabolism. The brain integrates multiple metabolic inputs from the periphery through nutrients, gut-derived satiety signals and adiposity-related hormones. The brain modulates various aspects of metabolism, such as food intake, energy expenditure, insulin secretion, hepatic glucose production and glucose/fatty acid metabolism in adipose tissue and skeletal muscle. Highly coordinated interactions between the brain and peripheral metabolic organs are critical for the maintenance of energy and glucose homeostasis. Defective crosstalk between the brain and peripheral organs contributes to the development of obesity and type 2 diabetes. Here we comprehensively review the above topics, discussing the main findings related to the role of the brain in the homeostatic regulation of energy and glucose metabolism.
In normal individuals, food intake and energy expenditure are tightly regulated by homeostatic mechanisms to maintain energy balance. Substantial evidence indicates that the brain, particularly the hypothalamus, is primarily responsible for the regulation of energy homeostasis.1 The brain monitors changes in the body energy state by sensing alterations in the plasma levels of key metabolic hormones and nutrients. Specialized neuronal networks in the brain coordinate adaptive changes in food intake and energy expenditure in response to altered metabolic conditions ( Figure 1 ).2, 3.
