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A combination of soon-to-be released Biotechnology is expected to extend of lifespans almost tenfold with the help through emerging technologies such as CRISPR or Senolytics. These Anti Aging treatments are meant to stop and even reverse the aging process so that anyone could get young and healthy again. Many companies such as SENS or Jeff Bezos, but even countries like Japan are working on it to deal with an aging population.

TIMESTAMPS:
00:00 A new Beginning for Longevity.
00:44 Direct Gene Editing.
02:32 Anti Aging Vaccines.
04:44 Longevity Gene Therapy.
07:39 How does Aging work?
09:49 Last Words.

#longevity #biotech #futurology

New kidney research from the University of Virginia School of Medicine is raising concerns that long-term use of drugs commonly prescribed to treat high-blood pressure and heart failure could be contributing to kidney damage.

Patients should continue taking the medications, which include the well-known and widely used ACE inhibitors, the researchers say. But the scientists are urging studies to better understand the drugs’ long-term effects.

Our studies show that renin-producing cells are responsible for the damage. We are now focusing on understanding how these cells, which are so important to defend us from drops in blood pressure and maintain our well-being, undergo such transformation and induce kidney damage. What is needed is to identify what substances these cells make that lead to uncontrolled vessel growth.

According to recent studies, more than a third of astronauts become momentarily anemic during space travel due to the enormous loss of red blood cells, including that of Tim Peake. Since the symptoms only appear with gravity, this does not cause problems until they arrive.

A new study reveals that populating other planets, like those envisioned by entrepreneur Elon Musk, may be more complex than previously assumed, based on the discovery of “space anemia.”

In addition, they suggested that it might deter those predisposed to heart illness, such as angina, from participating in the growing space tourism industry.

Researchers at University College London (UCL), Universidade de Santiago de Compostela (USC) and biopharma firm FabRx, have managed to convert an everyday smartphone into an on-demand personalized drug 3D printer.

Using the visible light created by a mobile phone screen, the modified M3DIMAKER LUX system has already proven capable of 3D printing blood-thinning tablets in specific shapes, sizes and dosages. Operable via a user-friendly app, it’s hoped that with further R&D, the team’s machine could be deployed in future by those living in isolated areas, under the remote supervision of GPs to ensure patient safety.

“This novel system would help people who need precise dosages that differ from how a medication is typically sold, as well as people whose required dosage may change regularly,” said the study’s lead author Xiaoyan Xu. “The tablet’s shape and size are also customizable, which enables flexibility in the rate at which the medication gets released into the bloodstream.”

A new work by the Nanomol Group, belonging to the CIBER-BBN network, together with a team from the University of Rome Tor Vergata, presents new nanovesicles capable of crossing biological barriers such as cell membranes, while maintaining their sensing capacity, which makes them attractive probes for intracellular detection of biomarkers.

“The development of probes capable of sensing the biological environment and signaling the presence of a specific target molecule is a challenge with relevance in a variety of biomedical applications, from to diagnostic tools,” says Mariana Köber, ICMAB researcher and corresponding author of the study, together with Nora Ventosa, from ICMAB, and Alessandro Porchetta, from the University of Rome Tor Vergata.

This work, which has been published in Advanced Functional Materials, presents the design of fluorescent nanovesicles functionalized with biomimetic DNA capable of translating their binding to a target molecule into an optical output, through a change in Förster resonance energy transfer (FRET) and fluorescent emission.

In a scene straight out of a spy movie, an elderly couple reportedly escaped from an assisted living facility using some cunning military expertise—and an antiquated telecommunications method.

On March 2, 2020, a resident of a secure memory care unit in Elmcroft of Lebanon, a Tennessee nursing facility, “eloped” with his wife from the premises, according to a state report on the incident. (The Tennessean first reported the incident last month.) The man was admitted to Elmcroft with a diagnosis of dementia, while the woman was admitted with Alzheimer’s disease.

A stranger spotted the residents, who were safe, walking two blocks from Elmcroft about 30 minutes after they left and picked them up.

Brooklyn, New York-based Tarform Motorcycles began sketching out designs for its slick-looking electric motorcycles almost five years ago. Despite pandemic-related setbacks that delayed production, the company is now beginning deliveries on its first electric motorcycles.

These aren’t just any run-of-the-mill bikes though.

Unlike many of the electric motorcycles we see today that take on a more conventional design intended to please the widest audience, Tarform focused on a more bespoke, hand-made direction from the beginning.

Opinions: Give your opinions in the comments section.

3D printed lab meat, and plant based meats will be more widespread in our future. Would you eat stem cell 3D printed lab meat or plant based meat? Why or why not? What are the differences between natural vs unnatural. Growing up in Texas I know most Texans frown on it, as BBQ is a religion. Is 3D printing meat sustainable\.


Whether it comes from a plant or the cells of an animal, it’s becoming increasingly clear that the meat of the future will probably not be coming from the flesh of slaughtered animals. Instead, whether made from plants or cells, it will be formed into ‘meat’ by a 3D printer. In September of 2021, a Japanese team of researchers at the University of Osaka announced that they had 3D printed Wagyu beef. Beef connoisseurs will recognize the name; Wagyu beef is prized (and suitably priced) for its flavor and fat marbling. Legends abound about the cows such beef derives from, how they are allegedly coddled and massaged, fed a special diet that includes beer — but much of those tales are either exaggerated or pure urban legend. As Joe Heitzeberg, the co-founder and CEO of Crowd Cow explains, There are four breeds native to Japan. Of those four breeds, one of the breeds is genetically unique. It has a genetic predisposition to create this crazy marbling of fat on the inside of muscle tissue. No other livestock does that. The researchers at the University of Osaka used two different types of stem cells from Wagyu cows to create cultured meat, growing living animal cells onto some type of matrix where they are then incubated and grown into animal tissue that has never been part of a living animal. There are currently no reports on the taste of the cultured Wagyu beef but we can assume it’s ‘good’ and given a little time, the technology should be able to produce excellent Wagyu cultured meat — at what price, however, is another big question mark. But there’s another simpler solution that could be a better meat replacement than cultured meat, as even meat grown from stem cells still contains cholesterol and some of the negative health concerns associated with animal protein. Plant-based imitation meat is also being created with 3D printers, and the results are surprising even hardcore meat lovers.

In November 2021, the UK’s Guardian newspaper highlighted the 3D steak produced by Israeli startup Redefine Meat after celebrity chef Marco Pierre White invited chefs, investors connoisseurs, and former winners of the MasterChef cooking show to taste it. This vegan 3D steak made with a 3D printer has a secret formula, but according to the Guardian, it includes soy, pea protein, and other vegetables such as beetroot, chickpeas, and coconut fat. But the reason it’s winning over meat lovers is the unique idea of printing it in layers. With a layer of ‘alternative fat’ made from plant-based materials, and then a layer of ‘alternative muscle’ also made from plants, the imitation meat no longer has a single texture — but like real meat — contains different flavors and textures in different areas. According to the experts gathered by celebrity Chef White, this ‘alt-meat’ is by far the closest synthetic approximation ever.

In a first, U.S. surgeons transplant pig heart into human patient.


Unusual opportunity

Last week’s procedure marks the first time that a pig organ has been transplanted into a human who has a chance to survive and recover. In 2021, surgeons at New York University Langone Health transplanted kidneys from the same line of genetically modified pigs into two legally dead people with no discernible brain function. The organs were not rejected, and functioned normally while the deceased recipients were sustained on ventilators.

Aside from that, most research has so far taken place in non-human primates. But researchers hope that the 7 January operation will further kick-start clinical xenotransplantation and help to push it through myriad ethical and regulatory issues.

Using a brain computer interface, the man cut and ate food with thought-controlled robotic hands. A man paralyzed from the neck down has used two robot arms to cut food and serve himself — a big step in the field of mind-controlled prosthetics.

Robert “Buz” Chmielewski, age 49, has barely been able to move his arms since a surfing accident paralyzed him as a teenager. But in January of 2019, he got renewed hope, when doctors implanted two sets of electrodes in his brain, one in each hemisphere.

The goal was that this brain computer interface would help Chmielewski regain some sensation in his hands, enable him to mentally control two prosthetic arms, and even feel what he is touching. man paralyzed from the neck down has used two robot arms to cut food and serve himself — a big step in the field of mind-controlled prosthetics.