Lifeboat Foundation: Safeguarding Humanity
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Category: neuroscience

Many of you will likely already know who Professor George Church is and that he is an important and senior member of the research community engaged in treating the aging processes to prevent or reverse age-related diseases, not to mention all kinds of other applications for genetic engineering. For those who are not familiar with him a short bio follows.

George Church is a professor at Harvard & MIT, the co-author of over 425 papers, 95 patent publications and the book Regenesis. He developed the methods used for the first genome sequence back in 1994 and he was instrumental in reducing the costs since then using next generation sequencing and nanopores plus barcoding, DNA assembly from chips, genome editing, writing and re-coding.

He co-initiated the Genome projects in 1984 and 2005 to create and interpret the world’s only open-access personal precision medicine datasets. He was also involved in launching the BRAIN Initiative in 2011.

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Theoretical physicist Lucien Hardy is pushing wants to push the boundaries of quantum physics by performing a Bell test using humans as links. This could potentially shed light on the existence of human consciousness and just what it is made of.

Perhaps one of the most intriguing and interesting phenomena in quantum physics is what Einstein referred to as a “spooky action at a distance” — also known as quantum entanglement. This quantum effect is behind what makes quantum computers work, as quantum bits (qubits) generally rely on entanglement to process data and information. It’s also the working theory behind the possibility of quantum teleportation.

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Become a citizen neuroscientist.

By playing Mozak you can advance our understanding of the brain. Each player becomes a neuroscientist that maps the structure of individual neurons. In doing so, you also receive feedback from experts at the Allen Institute for Brain Science and contribute to their massive effort to solve the secrets of the brain.

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“He learns to manage his image in the minds of others, and finds himself reflected, as in a mirror, through the interface of language and non-verbal communication […] The self is not unitary and separate from others; peopling occurs in the context of mutual-mental-modeling relationships, which continue to affect each person when he is alone…” sarah perry.

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But if there is some kind of unifying computational principle governing our grey matter, what is it? Dr. Tsien has studied this for over a decade, and he believes he’s found the answer in something called the Theory of Connectivity.

“Many people have long speculated that there has to be a basic design principle from which intelligence originates and the brain evolves, like how the double helix of DNA and genetic codes are universal for every organism,” Tsien said. “We present evidence that the brain may operate on an amazingly simple mathematical logic.”

The Theory of Connectivity holds that a simple algorithm, called a power-of-two-based permutation taking the form of n=2i-1 can be used to explain the circuitry of the brain. To unpack the formula, let’s define a few key concepts from the theory of connectivity, specifically the idea of a neuronal clique. A neuronal clique is a group of neurons which “fire together” and cluster into functional connectivity motifs, or FCMs, which the brain uses to recognize specific patterns or ideas. One can liken it to branches on a tree, with the neuronal clique being the smallest unit of connectivity, a mere twig, which when combined with other cliques, link up to form an FCM. The more complex the idea being represented in the brain, the more convoluted the FCM. The n in n=2i-1 specifies the number of neuronal cliques that will fire in response to a given input, i.

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Imagine a world in which you’re 90 years old and nowhere near middle-aged. An app on your phone has hacked your DNA code, so you know exactly when to go to the doctor to receive gene therapy to prevent all the diseases you don’t yet have. A microchip in your skin sends out a signal if you’re at risk of developing a wrinkle — so you step out of the sun and hotfoot it to your dermatologist. Every evening you sync your brain-mapping device with The Cloud, so even if you were caught up in a fatal accident you’d still be able to cheat death — every detail of your life would simply be downloaded to one of the perfect silicon versions you’d had made of yourself, ensuring you last until at least your 1,000th birthday.

This may sound like science fiction but it could be your fate — provided you can afford it. If current research develops into medicine, in the London of the future the super-rich won’t simply be able to buy the best things in life, they’ll be able to buy life itself by transforming themselves into a bio-engineered super-race, capable of living, if not forever, then for vastly longer than the current UK life expectancy of 81 years.

The science of turning back the clock has never been more advanced. In Boston, a drug capable of reversing half a lifetime of ageing in mice is about to be tested on humans in a medical trial monitored by NASA. NMN is a compound found naturally in broccoli which boosts levels of NAD, a protein involved in energy production that depletes as we get older. Professor David Sinclair, who headed up the initial research at Australia’s University of New South Wales, doses himself with 500mg daily, and claims that he has already become more youthful. According to blood tests analysing the state of the 48-year-old’s cells, prior to taking the pills Sinclair was in the same physical shape as a 57-year-old, but now he’s ‘31.4’.

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