Paralysis used to mean a life sentence of immobility with no way out—until now.
Back in 2010, Ian Burkhart suffered a devastating injury that would leave him mostly paralyzed. Even though he was still able to move his shoulders and elbows, he had lost sensation in his hands. That was until Patrick Ganzer at Battelle Memorial Institute fast-forwarded biotech into the future by developing a brain implant that would turn Burkhart’s life around. When the implant connects to a specialized brain-computer interface, it does something that has never been done before and has restored both movement and touch in his right hand.
While we might often take our sense of touch for granted, for researchers developing technologies to restore limb function in people paralyzed due to spinal cord injury or disease, re-establishing the sense of touch is an essential part of the process. And on April 23 in the journal Cell, a team of researchers at Battelle and the Ohio State University Wexner Medical Center report that they have been able to restore sensation to the hand of a research participant with a severe spinal cord injury using a brain-computer interface (BCI) system. The technology harnesses neural signals that are so miniscule they can’t be perceived and enhances them via artificial sensory feedback sent back to the participant, resulting in greatly enriched motor function.
“We’re taking subperceptual touch events and boosting them into conscious perception,” says first author Patrick Ganzer, a principal research scientist at Battelle. “When we did this, we saw several functional improvements. It was a big eureka moment when we first restored the participant’s sense of touch.”
The participant in this study is Ian Burkhart, a 28-year-old man who suffered a spinal cord injury during a diving accident in 2010. Since 2014, Burkhart has been working with investigators on a project called NeuroLife that aims to restore function to his right arm. The device they have developed works through a system of electrodes on his skin and a small computer chip implanted in his motor cortex. This setup, which uses wires to route movement signals from the brain to the muscles, bypassing his spinal cord injury, gives Burkhart enough control over his arm and hand to lift a coffee mug, swipe a credit card, and play Guitar Hero.
Stephen Wolfram is a cult figure in programming and mathematics. He is the brains behind Wolfram Alpha, a website that tries to answer questions by using algorithms to sift through a massive database of information. He is also responsible for Mathematica, a computer system used by scientists the world over.
Last week, Wolfram launched a new venture: the Wolfram Physics Project, an ambitious attempt to develop a new physics of our Universe.
The new physics, he declares, is computational. The guiding idea is that everything can be boiled down to the application of simple rules to fundamental building blocks.
A brain-computer interface has helped a man with a severe spinal cord injury move and feel using a hand again, letting him carefully lift light objects such as a paper cup.
US researchers report that they have been able to restore sensation to the hand of a research participant with a severe spinal cord injury using a brain-computer interface (BCI) system.
In a paper published on Nature Communications in 20 April 2020 by (read the original paper), Tianda Fu et al. from the University of Massachusetts Amherst proposed a new kind of diffusive memristor based on the protein nanowires sourced from the bacterium named Geobacter sulfurreducens that can potentially resolve the problem. The artificial neurons built on such memristors can function on the level of biological voltages, and they express “temporary integration feature that is similar to real neurons in our brain” according to the authors.
MANILA, Philippines — A dengue case forecasting system using space data made by Philippine developers won the 2019 National Aeronautics and Space Administration’s International Space Apps Challenge. Over 29,000 participating globally in 71 countries, this solution made it as one of the six winners in the best use of data, the solution that best makes space data accessible, or leverages it to a unique application.
Dengue fever is a viral, infectious tropical disease spread primarily by Aedes aegypti female mosquitoes. With 271,480 cases resulting in 1,107 deaths reported from January 1 to August 31, 2019 by the World Health Organization, Dominic Vincent D. Ligot, Mark Toledo, Frances Claire Tayco, and Jansen Dumaliang Lopez from CirroLytix developed a forecasting model of dengue cases using climate and digital data, and pinpointing possible hotspots from satellite data.
Correlating information from Sentinel-2 Copernicus and Landsat 8 satellites, climate data from the Philippine Atmospheric, Geophysical and Astronomical Services Administration of the Department of Science and Technology (DOST-PAGASA) and trends from Google search engines, potential dengue hotspots will be shown in a web interface.
Using satellite spectral bands like green, red, and near-infrared (NIR), indices like Fraction of Absorbed Photosynthetically Active Radiation (FAPAR) and Normalized Difference Vegetation Index (NDVI) are calculated in identifying areas with green vegetation while Normalized Difference Water Index (NDWI) identifies areas with water. Combining these indices reveal potential areas of stagnant water capable of being breeding grounds for mosquitoes, extracted as coordinates through a free and open-source cross-platform desktop geographic information system QGIS.
“AEDES aims to improve public health response against dengue fever in the Philippines by pinpointing possible hotspots using Earth observations,” Dr. Argyro Kavvada of NASA Earth Science and Booz Allen Hamilton explained.
The DOST-Philippine Council for Industry, Energy and Emerging Technology Research and Development (DOST-PCIEERD) deputy executive director Engr. Raul C. Sabularse said that the winning solution “benefits the community especially those countries suffering from malaria and dengue, just like the Philippines. I think it has a global impact. This is the new science to know the potential areas where dengue might occur. It is a good app.”
“It is very relevant to the Philippines and other countries which usually having problems with dengue. The team was able to show that it’s not really difficult to have all the data you need and integrate all of them and make them accessible to everyone for them to be able to use it. It’s a working model,” according to Monchito B. Ibrahim, industry development committee chairman of the Analytics Association of the Philippines and former undersecretary of the Department of Information and Communications Technology.
The leader of the Space Apps global organizing team Dr. Paula S. Bontempi, acting deputy director of the Earth Science Mission, NASA’s Science Mission Directorate remembers the pitch of the winning team when she led the hackathon in Manila. “They were terrific. Well deserved!” she said.
“I am very happy we landed in the winning circle. This would be a big help particularly in addressing our health-related problems. One of the Sustainable Development Goals (SDGs) is on Good Health and Well Being and the problem they are trying to address is analysis related to dengue,“ said Science and Technology secretary Fortunato T. de la Peña. Rex Lor from the United Nations Development Programme (UNDP) in the Philippines explained that the winning solution showcases the “pivotal role of cutting-edge digital technologies in the creation of strategies for sustainable development in the face of evolving development issues.”
U.S Public Affairs counselor Philip W. Roskamp and PLDT Enterprise Core Business Solutions vice president and head Joseph Ian G. Gendrano congratulates the next group of Pinoy winners.
Sec. de la Peña is also very happy on this second time victory for the Philippines on the global competition of NASA. The first winning solution ISDApp uses “data analysis, particularly NASA data, to be able to help our fishermen make decisions on when is the best time to catch fish.” It is currently being incubated by Animo Labs, the technology business incubator and Fab Lab of De La Salle University in partnership with DOST-PCIEERD. Project AEDES will be incubated by Animo Labs too.
University president Br. Raymundo B. Suplido FSC hopes that NASA Space Apps would “encourage our young Filipino researchers and scientists to create ideas and startups based on space science and technology, and pave the way for the promotion and awareness of the programs of our own Philippine space agency.”
Philippine vice president Leni Robredo recognized Space Apps as a platform “where some of our country’s brightest minds can collaborate in finding and creating solutions to our most pressing problems, not just in space, but more importantly here on Earth.”
“Space Apps is a community of scientists and engineers, artists and hackers coming together to address key issues here on Earth. At the heart of Space Apps are data that come to us from spacecraft flying around Earth and are looking at our world,” explained by Dr. Thomas Zurbuchen, NASA associate administrator for science.
“Personally, I’m more interested in supporting the startups that are coming out of the Space Apps Challenge,” according to DOST-PCIEERD executive director Dr. Enrico C. Paringit.
In the Philippines, Space Apps is a NASA-led initiative organized in collaboration with De La Salle University, Animo Labs, DOST-PCIEERD, PLDT InnoLab, American Corner Manila, U.S. Embassy, software developer Michael Lance M. Domagas, and celebrates the Design Week Philippines with the Design Center of the Philippines of the Department of Trade and Industry. It is globally organized by Booz Allen Hamilton, Mindgrub, and SecondMuse.
Space Apps is a NASA incubator innovation program. The next hackathon will be on October 2–4, 2020.