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Top scientists at Roche Holding AG and AstraZeneca Plc are sizing up potential allies in the fight against cancer: the trillions of bacteria that live in the human body.

“Five years ago, if you had asked me about bacteria in your gut playing an important role in your systemic immune response, I probably would have laughed it off,” Daniel Chen, head of cancer immunotherapy research at Roche’s Genentech division, said in a phone interview. “Most of us immunologists now believe that there really is an important interaction there.”

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Smart data discovery company Bottlenose Inc has announced the addition of two major new sources to its ever-expanding data library: LexisNexis, which stores offline data from government, academic, and industry sources; and Flashpoint, which stores data from the deep web and the dark web.

Bottlenose co-founder and CEO Nova Spivack told me that these new integrations represent a huge boost in power for the platform, allowing businesses to better anticipate new threats and opportunities as they arise.

Spivack explained that by adding the data from LexisNexis and Flashpoint to Bottlenose’s existing sources, the platform can better detect new patterns as they form by comparing a variety of signals that might seem insignificant on their own.

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Let’s just hypothesize a little on this topic: let’s say Apple goes ahead and gives in to the US Government and enables government to access the phone’s info. Does Apple have any protection in the future from lawsuits from it’s customers in situations where their own customers information is hacked by criminals and published to the world or used for illegal activities? Because I do see in the future more lawsuits coming at the tech companies for not ensuring their platforms and devices are un-hackable. So, if the government has its way; what protections does tech have now with any future lawsuits by consumers and other businesses?


His comments come during the ongoing legal battle over an iPhone used by Syed Farook, one of the individuals responsible for the San Bernardino, Calif. mass shooting December 2. “I don’t think requiring backdoors with encryption is either going to be an effective way to increase security or is really the right thing to do for just the direction that the world is going to”.

This is because First Amendment treats computer code as speech and according to Apple, meeting the demands of the government would be equivalent to “compelled speech and viewpoint discrimination”.

The Electronics Frontier Foundation (EFF) has said it will be filing an amicus brief in support of Apple with the courts.

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I have spent the last 30 years in various aspects of the biopharmaceutical industry, which for the most part has been a very rewarding experience.

However, during this time period, having been immersed many different components of therapeutic development and commercialization, one thing has always bothered me: a wide array of promising research never makes it off the bench to see the translational light of day, and gets lost in the historical scientific archives.

bqiinclab

I always believed that scientific progress happened in a very linear narrative, with each new discovery supporting the next, resulting ultimately in an eventual stairway of scientific enlightenment.

What the reality turned out to be was much more of a fragmented, research “evolutionary tree”, with dozens of potential pathways, only very few branches of which ever resulted in scientific maturity, and not always the most fruitful ones by any means.

The premature extinction of these promising discovery pathways were the result of a variety of factors, including, but not limited to, funding priorities, competing industrial interests, “out of vogue” concepts, lack of intellectual properties, non-existent regulatory models, conflicted legislative initiatives, and even religious implications.

In 2016, as in previous years, we continue to see these “valleys of death” swallow up pathways of scientific possibility, with few popular segments attracting the majority of attention and support.

gene sequencing

The preponderance of resources focused on the somatic mutation model of carcinogenesis, despite an endless range of research highlighting that the disease is extremely heterogenic and rarely ever follows such a clonal model, is one example that continues to be inappropriately manifested in the oncology system, decades into the “war on cancer”.

On a similar plane, the jettisoning of most studies of the biophysical aspects of human genetics, despite the gross incompleteness offered by the central dogma to explain higher biological form and function, is another example that has become all too pervasive in the research community.

And then there are the areas of human consciousness, memory, and information processing / storage, where in many ways we are still operating in the dark ages, with materialists and dualists battling it out for centuries.

One topic that I have written quite a bit about is that of death, specifically that of the death of the human brain — http://www.singularityweblog.com/is-death-reversible/

brainimage

While I am a staunch supporter and advocate of the life-extension / anti-aging movement, I am equally vocal about our need to develop technologies, products, and services that can actually reverse our ultimate transition between the living and dead states, a transition that occurs annually for 60 million humans around the globe.

Death, however, is unfortunately seen by many as a natural, biological progression for human beings, and in many circles, deemed an unnecessary area of scientific research and exploration.

I beg to differ.

Far too often, death arrives too early and too unexpectedly for many of us and our loved ones. And the best modern medicine has to offer today is “Sorry. There is nothing else we can do.”

But what if there was?

There are a variety of species across the natural world that are capable of regenerating and repairing themselves from forms of severe CNS damage that bring them to the transitional grey zone between life and death. Along the evolutionary timeline however, this ability gradually disappeared hundreds of millions of years ago and does not manifest in higher species.

lizard and lady

Now, in the 21st century, with the convergence of the disciplines of regenerative biology, cognitive neuroscience, and clinical resuscitation, we may finally be poised to take back these capabilities for humans.

Over the years, clinical science has focused heavily on preventing such life and death transitions and made some initial progress with suspended animation technologies, such as therapeutic hypothermia. But once we transition through the brain death window, currently defined by the medical establishment as “irreversible” (per the 1968 Ad Hoc Committee of the Harvard Medical School definition), we are technically no longer alive.

surgeons

To add insult to injury, a human can be declared dead, even while our bodies can still circulate blood, digest food, excrete waste, balance hormones, grow, sexually mature, heal wounds, spike a fever, and gestate and deliver a baby. It is even acknowledged by thought leaders that recently brain dead humans still may have residual blood flow and electrical nests of activity in their brains, just not enough to allow for an integrated functioning of the organism as a whole.

Several prominent cases in the media over the past few years have further served to highlight the current situation, as well as the substantial anatomical and functional differences between the state known as brain death, and other severe disorders of consciousness, such as coma, and the vegetative and minimally conscious states.

It is now time to take the necessary steps to provide new possibilities of hope, in order to counter the pain, sorrow, and grief that is all too pervasive in the world when we experience a loved one’s unexpected or untimely death, due to lesions which might be potentially reversible with the application of promising neuro-regeneration and neuro-reanimation technologies and therapies.

bqaproduction

It is time to undertake the required research, based on 2016 technological knowledge, in order to bring about such transformational change.

My name is Ira S. Pastor and I am the CEO of the biotechnology company Bioquark Inc.

Welcome to the unveiling of the Reanima project.

Reanima Video

I find this all amusing. However, wide spread adoption is a hurdle that has to be addressed first around AI; and at it’s core is the lack of trust by consumers & businesses around technology that still has not eradicated and blocked cyber hacking and attacks.


Martine Rothblatt takes on the notion that AI is dangerous to humanity.

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This article is a year old, but it is the first I’ve seen it. This guy has access to hundreds of millions of dollars per year and has this wonderful quote to go with it: “If you ask me today, is it possible to live to be 500? The answer is yes,” Bill Maris says.


Bill Maris has $425 million to invest this year, and the freedom to invest it however he wants. He’s looking for companies that will slow aging, reverse disease, and extend life.

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https://youtube.com/watch?v=b28Pquo54ek

Dear readers,

My son Ethan Kurzweil — who is a partner at Bessemer Ventures Partners — tracks the future of web innovation, social and legal concerns about privacy, and start-ups who have an edge with their business or consumer applications, like team sourcing or software-as-a-service.

He appeared on C • NBC business affairs show Power Lunch. Episode debated the recent news about the US government and law enforcement asking Apple to release private data on an iPhone used by terrorists.

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