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Category: 3D printing

Researchers from Beijing and Philadelphia develop a method to 3D print embryonic stem cells in highly uniform blocks.

Researchers from Tsinghua University in Beijing, China and Drexel University in the US have developed an extrusion-based 3D printing method to produce highly uniform “blocks” of embryonic stem cells. These blocks are a grid-like 3D structure that was able to demonstrate cell viability and rapid self-renewal while maintaining high pluripotency. Lead author Wei Sun says, “It was really exciting to see that we could grow embryoid body in such a controlled manner. The grown embryoid body is uniform and homogenous, and serves as much better starting point for further tissue growth.”

Other common methods of printing stem cells are either done in 2D or with the “suspension” method, but these methods do not produce cells with the same cell uniformity and homogenous proliferation as that of the 3D method. This new method would enable researchers to perform experiments on tissue regeneration. Another author on the paper, Rui Yao, adds, “Our next step is to find out more about how we can vary the size of the embryoid body by changing the printing and structural parameters, and how the varying the embryoid body size leads to “manufacture” of different cell types.”

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The human brain is a fragile and powerful tool, and is also fully dependent on a sturdy skull to keep it secure and intact. Unfortunately for some, there is a need for cranial reconstruction on people who were either born with a skull-related deficiency or critically injured in the head area. 3D printing has shown itself to be a potential game-changer in this regard; we have already witnessed successful titanium mesh skull replacements for one Chinese farmer and even a three-year-old girl born with congenital hydrocephalus. Now, researchers out of Western Australia are developing a new advanced 3D printing method that involves reconstructing the human skull from stem cell cultures.

3dprinting_rph

The project, which is taking place within the Royal Perth Hospital and is being funded by the State Government, will provide their patients with damaged or surgically removed skull fragments with a high-quality cranial reconstruction surgery. The 3D printed stem cell-based skull replacement can potentially increase the success rate and the post-surgical quality of life of patients who require this intensive surgery.

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Coronary artery structure being 3-D bioprinted (credit: Carnegie Mellon University College of Engineering)

Carnegie Mellon scientists are creating cutting-edge technology that could one day solve the shortage of heart transplants, which are currently needed to repair damaged organs.

“We’ve been able to take MRI images of coronary arteries and 3-D images of embryonic hearts and 3-D bioprint them with unprecedented resolution and quality out of very soft materials like collagens, alginates and fibrins,” said Adam Feinberg, an associate professor of Materials Science and Engineering and Biomedical Engineering at Carnegie Mellon University.

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You might not be able to control the 7Bot robotic arm with your mind or your eyes, but at least it’ll only cost you around $350 — cheaper than an iPhone, its creators point out — to get one. Even better, you don’t need to know how to code to program it: just physically guide the arm or use a gesture control device like a Kinect or a Leap motion sensor to make it mimic your movements. In the video below the fold and on its Kickstarter page, you can see it doing calligraphy after a team member’s grandfather physically taught it how. The team also managed make it paint cherry blossoms and do basic mathematics, and we’ll bet you can teach it other productive things, like how to terrorize your cat.

If you prefer the more hands-off approach, you can remotely control it using its 3D visualization app on a computer. And, in case you’re more tech-savvy than the average user, you can program it using the C and C++ open source APIs the 7Bot team provides. In addition to the basic model, the team also offers packages with more features, such as a version with two arms and one that comes with a 3D printer, though they’re also understandably more expensive. According to its campaign page, rewards should start shipping out as soon as January 2016, but as always, it’s best not to treat Kickstarter and other crowdfunding websites as a store.

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As of this month, over 4,000 Americans are on the waiting list to receive a heart transplant. With failing hearts, these patients have no other options; heart tissue, unlike other parts of the body, is unable to heal itself once it is damaged. Fortunately, recent work by a group at Carnegie Mellon could one day lead to a world in which transplants are no longer necessary to repair damaged organs.

“We’ve been able to take MRI images of coronary arteries and 3-D images of embryonic hearts and 3-D bioprint them with unprecedented resolution and quality out of very like collagens, alginates and fibrins,” said Adam Feinberg, an associate professor of Materials Science and Engineering and Biomedical Engineering at Carnegie Mellon University. Feinberg leads the Regenerative Biomaterials and Therapeutics Group, and the group’s study was published in the October 23 issue of the journal Science Advances. A demonstration of the technology can be seen below.

“As excellently demonstrated by Professor Feinberg’s work in bioprinting, our CMU researchers continue to develop novel solutions like this for problems that can have a transformational effect on society,” said Jim Garrett, Dean of Carnegie Mellon’s College of Engineering. “We should expect to see 3-D bioprinting continue to grow as an important tool for a large number of medical applications.”

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If you think the image above looks frightening, you’re right. The crazy contraption pictured in the image is the first portable railgun, a futuristic projectile launcher associated most commonly with the military or NASA. The man in the image above isn’t in the military, and he’s not a NASA engineer. Instead, he’s a civilian who used some engineering smarts, some widely available parts and a 3D printer to create a functioning weapon that can fire graphite, aluminum, tungsten and even plasma projectiles at speeds of more than 560 mph.

And then there’s the best part: There are videos of this homemade railgun in action.

MUST READ: The iPhone I couldn’t live with

Little is known about Imgur user “NSA_Listbot” beyond the fact that he’s just short of being a wizard with AutoCAD and a 3D printer. The man took to Imgur over the weekend to share what may very well be one of the most amazing and terrifying DIY projects that has even been attempted. And he didn’t just attempt it, he built it.

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Created by Russian engineer Nikita Chen-yun-tai, the new Apis Cor 3D printer is powerful enough to print a building in one day, yet small enough to be moved with minimal preparation and transportation costs. This portability allows users to print a building in one location and easily move the Apis Cor the next day to another spot. It promises to revolutionize the use of 3D printers in construction, especially in developing nations where low-cost, efficient printing is critical.

The 3D printing of houses is not a new idea — companies have been using the tenets of additive manufacturing for years. What makes the compact Apis Cor printer unique is the unit’s small size — it measures 16.4 ft by 5 ft, weighs 2.5 tons and can be assembled within 30 minutes. As a result, the Apis Cor can be moved easily without the need for an expensive method of transportation and setup. It requires no site preparation and no testing before use, which means it can be dropped on site and deployed right away after assembly.

Related: A Chinese company assembled this 3D-printed home in just three hours.

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1. A heart of foam.
2. Artificial arteries.
3. Brain implants.
4. Robotic hand that can recognize objects by Feel.
5. Upside-Down Rover to explore Europa.

Welcome to #18 Avatar Technology Digest. Again, get ready for exciting news on Technology, Medical Cybernetics and Artificial Intelligence. Thank you for watching us. You are welcome to Subscribe, follow us in social media, leave your comments and join the conversation. And here are the top stories of the last week.

1) A heart of foam could replace your own. Existing artificial hearts have multiple moving parts, which increases the chance of failure, but this new device is just a single piece of material. Researchers inspired by soft robots have built a pumping artificial heart that could one day replace the real deal.
The team of Bioengineers at Cornell University build their robots out of a solid, plastic foam, which naturally has an interconnected network of tubes to let air flow – just as our muscles are permeated by blood vessels. A solid coating of plastic seals everything inside like a skin.

2) Researchers at QMUL have developed a way of assembling organic molecules into complex tubular tissue-like structures without the use of moulds or techniques like 3D printing. Self-assembling material can grow and change shape and one day could lead to artificial arteries.
The method uses solutions of peptide and protein molecules that, upon touching each other, self-assemble to form a dynamic tissue at the point at which they meet. As the material assembles itself it can be easily guided to grow into complex shapes.
This discovery could lead to the engineering of tissues like veins, arteries, or even the blood-brain barrier. The technique could also contribute to the creation of better implants, complex tissues, or more effective drug screening methods.

3) Neural Implant Enables Paralyzed ALS Patient to Type Six Words per Minute.
A massive collaboration of doctors and computer scientists gets one step closer to mind-controlled devices.
An eclectic team of researchers affiliated with BrainGate, a consortium of neuroscientists, engineers, computer scientists, and mathematicians, have published a study in Nature Medicine that profiles two subjects who control a cursor with their thoughts more deftly than previous systems allowed.
Earlier versions of the system allowed subjects to perform such tasks as drinking from a coffee thermos using a robotic arm, or playing simple games. The latest version brings finer control and ease of use. One participant was even able to type at a rate of six words a minute, using software originally developed to help people type type with eye movement.

4) Robots have many strong suits, but delicacy traditionally hasn’t been one of them. Rigid limbs and digits make it difficult for them to grasp, hold, and manipulate a range of everyday objects without dropping or crushing them. Now Soft robotic gripper can gently pick up and identify wide array of objects.
At a conference this month, researchers from Distributed Robotics Lab demonstrated a 3D-printed robotic hand made out of silicone rubber that can lift and handle objects as delicate as an egg and as thin as a compact disc.
Just as impressively, its three fingers have special sensors that can estimate the size and shape of an object accurately enough to identify it from a set of multiple items.

5) There’s a big ocean under the ice… NASA’s JPL team is working on a simple solution to get a sense of the deep ocean first: it’s working on the Buoyant Rover for Under-Ice Exploration. As you will see in the video, JPL tested it in choppy, methane-rich waters in Alaska.

TV Presenter: Olesya Yermakova @olesyayermakova.
Video: Vladimir Shlykov www.GetYourMedia.ru

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