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In one of the largest studies of its kind, researchers at Orlando Health are making new progress in finding ways to detect a traumatic yet sinister brain injury—and getting closer to preventing further damage.

Subconcussive injuries often show no symptoms or immediate effects, but can cause wear and tear on the brain over time with repeated injuries. The latest study, published in the journal BMJ Paediatrics Open, includes more than 700 emergency room patients—children and adults. The study gets us closer to developing a standard blood test to spot these injuries as early as possible.

“A unique feature of this study is that it includes patients who hit their heads but have no symptoms,” said Linda Papa, MD, lead author of the study and emergency medicine doctor at Orlando Health. “This group is rarely—if ever—included in biomarker studies.”

Scientists have identified a class of drugs that may have potential to treat a rare and deadly form of brain cancer that affects young children.

The research team, led by Ranjit Bindra, MD, PhD, and colleagues at the Yale Cancer Center, also included co-senior authors Charles Brenner, PhD, professor and DEO of biochemistry at the University of Iowa Carver College of Medicine, and Michael E. Berens, PhD, from the Translational Genomics Research Institute in Phoenix.

The findings, published Aug. 22 in Nature Communications, focus on Diffuse Intrinsic Pontine Glioma (DIPG), a rare, incurable cancer that affects the brainstem in children under age 10. Previous work had identified mutations in a gene called PPM1D as a cause of this cancer.

Nootropics are colloquially known as “smart drugs” – substances that increase cognitive function in healthy people. In this video, bestselling author Dave Asprey discusses two naturally occurring nootropics: caffeine and nicotine.

Microdosing one milligram of the latter — about 5 to 10 percent of a cigarette’s worth — may even protect against Alzheimer’s.

ME Conferences is organizing “18th International Conference on Gastroenterology and Digestive Disorders” during September 16–17, 2019, Dubai, UAE. Conference highlights the theme- Improving Access in Gastroenterology: From Past to Future.

Gastro Meet 2019 is a leading platform for a focused agenda of the current research in the field of gastroenterology which includes, guest lectures, keynotes, symposiums, workshops, exhibitions, panel discussions, and poster sessions. We invite Gastroenterologists, Hepatologists, General Physicians, Microbiologists, Oncologists, Surgeons, Researchers, Students, and Business delegates to join us at Dubai in August 2018 for the 2-day power packed Gastroenterologists Meet.

September 16 (Monday) — 17 (Tuesday)

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When it comes to age reversal and complex regeneration in humans, a basin of research has been put in front of us. How much do we know about the brain, consciousness, and death reversal? As Big Pharma makes a trillion dollars annually, are they interested in finding cures? What valuable lessons are we learning from evolution?

On this episode, we have an in-depth conversation about exciting developments in biology with Bioquark CEO, Ira Pastor.

Fronteirs offers open access. If you want to read full publications this is the place to do so. #enjoy


Download this month’s new releases including the latest research collections on Tinnitus, Brain Aging, Arboviral Infections, and many more! All eBooks are free to download, share and distribute.

Shape the future of your field — and publish your own eBook — by editing an article collection around your research area. Learn more about Research Topics or submit your suggestion to [email protected]

An international team of researchers with partial support from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) developed a new MRI technique that can capture an image of a brain thinking by measuring changes in tissue stiffness. The results show that brain function can be tracked on a time scale of 100 milliseconds – 60 times faster than previous methods. The technique could shed new light on altered neuronal activity in brain diseases.

The human brain responds almost immediately to stimuli, but non-invasive imaging techniques haven’t been able to keep pace with the brain. Currently, several non-invasive brain imaging methods measure brain function, but they all have limitations. Most commonly, clinicians and researchers use functional magnetic resonance imaging (fMRI) to measure brain activity via fluctuations in blood oxygen levels. However, a lot of vital brain activity information is lost using fMRI because blood oxygen levels take about six seconds to respond to a stimulus.

Since the mid-1990s, researchers have been able to generate maps of tissue stiffness using an MRI scanner, with a non-invasive technique called magnetic resonance elastography (MRE). Tissue stiffness can’t be measured directly, so instead researchers use MRE to measure the speed at which mechanical vibrations travel through tissue. Vibrations move faster through stiffer tissues, while vibrations travel through softer tissue more slowly; therefore, tissue stiffness can be determined. MRE is most commonly used to detect the hardening of liver tissue but has more recently been applied to other tissues like the brain.