Lifeboat Foundation: Safeguarding Humanity
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Bioquark, Inc., (http://www.bioquark.com) a company focused on the development of novel biologics for complex regeneration and disease reversion, and Revita Life Sciences, (http://revitalife.co.in) a biotechnology company focused on translational therapeutic applications of autologous stem cells, have announced that they have received IRB approval for a study focusing on a novel combinatorial approach to clinical intervention in the state of brain death in humans.

This first trial, within the portfolio of Bioquark’s Reanima Project (http://www.reanima.tech) is entitled “Non-randomized, Open-labeled, Interventional, Single Group, Proof of Concept Study With Multi-modality Approach in Cases of Brain Death Due to Traumatic Brain Injury Having Diffuse Axonal Injury” (https://clinicaltrials.gov/ct2/show/NCT02742857?term=bioquark&rank=1), will enroll an initial 20 subjects, and be conducted at Anupam Hospital in Rudrapur, Uttarakhand India.

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“We are very excited about the approval of our protocol,” said Ira S. Pastor, CEO, Bioquark Inc. “With the convergence of the disciplines of regenerative biology, cognitive neuroscience, and clinical resuscitation, we are poised to delve into an area of scientific understanding previously inaccessible with existing technologies.”

Death is defined as the termination of all biological functions that sustain a living organism. Brain death, the complete and irreversible loss of brain function (including involuntary activity necessary to sustain life) as defined in the 1968 report of the Ad Hoc Committee of the Harvard Medical School, is the legal definition of human death in most countries around the world. Either directly through trauma, or indirectly through secondary disease indications, brain death is the final pathological state that over 60 million people globally transfer through each year.

While human beings lack substantial regenerative capabilities in the CNS, many non-human species, such as amphibians, planarians, and certain fish, can repair, regenerate and remodel substantial portions of their brain and brain stem even after critical life-threatening trauma.

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Additionally, recent studies on complex brain regeneration in these organisms, have highlighted unique findings in relation to the storage of memories following destruction of the entire brain, which may have wide ranging implications for our understanding of consciousness and the stability of memory persistence.

“Through our study, we will gain unique insights into the state of human brain death, which will have important connections to future therapeutic development for other severe disorders of consciousness, such as coma, and the vegetative and minimally conscious states, as well as a range of degenerative CNS conditions, including Alzheimer’s and Parkinson’s disease,” said Dr. Sergei Paylian, Founder, President, and Chief Science Officer of Bioquark Inc.

Over the years, clinical science has focused heavily on preventing such life and death transitions and made some initial progress with suspended animation technologies, such as therapeutic hypothermia. However, once humans transition through the brain death window, currently defined by the medical establishment as “irreversible”, they are technically no longer alive, despite the fact that human bodies can still circulate blood, digest food, excrete waste, balance hormones, grow, sexually mature, heal wounds, spike a fever, and gestate and deliver a baby. It is even acknowledged by thought leaders that recently brain dead humans still may have residual blood flow and electrical nests of activity in their brains, just not enough to allow for an integrated functioning of the organism as a whole.

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“We look forward to working closely with Bioquark Inc. on this cutting edge clinical initiative,” said Dr. Himanshu Bansal, Managing Director of Revita Life Sciences.

About Bioquark, Inc.

Bioquark Inc. is focused on the development of natural biologic based products, services, and technologies, with the goal of curing a wide range of diseases, as well as effecting complex regeneration. Bioquark is developing both biological pharmaceutical candidates, as well as products for the global consumer health and wellness market segments.

About Revita Life Sciences

Revita Life Sciences is a biotechnology company focused on the development of stem cell therapies that target areas of significant unmet medical need. Revita is led by Dr. Himanshu Bansal MD, PhD. who has spent over two decades developing novel MRI based classifications of spinal cord injuries as well as comprehensive treatment protocols with autologous tissues including bone marrow stem cells, dural nerve grafts, nasal olfactory tissues, and omental transposition.

They deserve it too.

X2 Biosystems has received the Society for Brain Mapping and Therapeutics (SBMT) 2016 Pioneer in Healthcare Technology Innovations Award for developing its next-generation head impact measurement sensor technology, the company said.

X2´s “X-Patch” wearable impact sensor has become widely deployed and tested head impact monitoring device, used in a continually expanding range of athletic activities from football (youth, high school, collegiate, pro) to hockey, soccer, lacrosse, rugby, Australian rules football, baseball, field hockey, wrestling, boxing, taekwondo, mixed martial arts, skiing and BMX cycling.

The X-Patch is also being actively evaluated for use in military training applications.

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All true and good points. Until the under pinning technology and net infrastructures are update; all things connected will mean all things hackable.

Medical devices like pacemakers and insulin pumps will save many lives, but they also represent an opportunity to computer hackers who would use the Internet to cause havoc. Former futurist-in-residence at the FBI, Marc Goodman says it is easy to take for granted how connected we’ve already become to the Internet. Most American adults keep their phones within arm’s reach all day, and keep their devices on their nightstand while they sleep — and forget about actually remembering people’s phone numbers. That is a job we have outsourced to machines.

In this sense, says Goodman, we are already cyborgs. But digital devices connected to the Internet will continue to move inside our bodies, just as pacemakers and insulin pumps have. In his interview, Goodman discusses cases of computer hackers taking advantage of these devices’ connectivity to show how vulnerable we could soon become to their potentially destructive wishes. In one case, a hacker demonstrated he could release several weeks of insulin into a diabetic’s body, certain to cause a diabetic coma and death. In another, hackers induced epileptic seizures by hacking the Epilepsy Foundation’s webpage.

At bottom is the Internet of Things, a increasingly connected web of devices that will make our lives simpler and more efficient, but this network will also make us vulnerable in ways that are difficult to detect, let alone prevent. Goodman’s message is not that we need to constantly fear a new world of better health and convenience, but that we need to be aware of technology’s pitfalls in life.

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Interesting and will be important in brain/ neuro replicating and enhancements.

Memories formed in one part of the brain are replayed and transferred to a different area of the brain during rest, according to a new UCL study in rats.

The finding suggests that replay of previous experiences during rest is important for , a process whereby the brain stabilises and preserves memories for quick recall in the future. Understanding the physiological mechanism of this is essential for tackling amnesiac conditions such as Alzheimer’s disease, where memory consolidation is affected.

Lead researcher, Dr Freyja Ólafsdóttir (UCL Cell & Developmental Biology), said: “We want to understand how a healthy brain stores and accesses memories as this will give us a window into how conditions such as Alzheimer’s disease disrupt the process. We know people with Alzheimer’s have difficulty recalling the recent past but can often readily remember childhood memories, which seem more resilient. The parts of the brain we studied are some of the first regions affected in Alzheimer’s and now we know they are also involved in memory consolidation.”

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“Researchers at George Washington University have linked fast-food consumption to the presence of potentially harmful chemicals, a connection they argue could have “great public health significance.””

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Imagine shirts that act as antennas for smartphones or tablets, workout clothes that monitor fitness level or even a flexible fabric cap that senses activity in the brain!

All this will soon be possible as the researchers working on wearable electronics have been able to embroider circuits into fabric with super precision — a key step toward the design of clothes that gather, store or transmit digital information.

“A revolution is happening in the textile industry. We believe that functional textiles are an enabling technology for communications and sensing and one day, even for medical applications like imaging and health monitoring,” said lead researcher John Volakis from Ohio State University.

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The discomfort and stigma of loose or missing teeth could be a thing of the past as Griffith University researchers pioneer the use of 3D bioprinting to replace missing teeth and bone.

The three-year study, which has been granted a National Health and Medical Research Council Grant of $650,000, is being undertaken by periodontist Professor Saso Ivanovski from Griffith’s Menzies Health Institute Queensland.

As part of an Australian first, Professor Ivanovski and his team are using the latest 3D bioprinting to produce new, totally ‘bespoke,’ tissue engineered and gum that can be implanted into a patient’s jawbone.

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#nutrition #CrapScience

So after 40 years of prescribing low fat diets & demonising cholesterol, the largest & longest clinical experiment ever (40 years, 9,000 patients, randomly assigned diets) shows that “Patients who lowered their cholesterol, presumably because of the special diet, actually suffered MORE heart-related deaths than those who did not.”

In other words, if you’ve been cutting on steaks, butter etc. for 4 years or more, you may have INCREASED your mortality rate from heart disease by %8.

Oops?

Via Oxford Martin School @oxmartinschool

A fuller accounting of the results of a massive government-funded experiment on fatty foods challenges the conventional advice about what is healthy, and what is not.

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“DNA base pairing has been used for many years to direct the arrangement of inorganic nanocrystals into small groupings and arrays with tailored optical and electrical properties. The control of DNA-mediated assembly depends crucially on a better understanding of three-dimensional structure of DNA-nanocrystal-hybridized building blocks. Existing techniques do not allow for structural determination of these flexible and heterogeneous samples.”

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