Lifeboat Foundation: Safeguarding Humanity
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Category: futurism

As this example shows, 3D printing has come a long way, quickly. In February 2011, when The Economist ran a story called “Print me a Stradivarius”, the idea of printing objects still seemed extraordinary. Now, it is well established. Additive manufacturing, as it is known technically, is speeding up prototyping designs and is also being used to make customised and complex items for actual sale.

SLOWLY but surely the sole of a shoe emerges from a bowl of liquid resin, as Excalibur rose from the enchanted lake. And, just as Excalibur was no ordinary sword, this is no ordinary sole. It is light and flexible, with an intricate internal structure, the better to help it support the wearer’s foot. Paired with its solemate it will underpin a set of trainers from a new range planned by Adidas, a German sportswear firm.

Adidas intends to use the 3D-printed soles to make trainers at two new, highly automated factories in Germany and America, instead of producing them in the low-cost Asian countries to which most trainer production has been outsourced in recent years. The firm will thus be able to bring its shoes to market faster and keep up with fashion trends. At the moment, getting a design to the shops can take months. The new factories, each of which is intended to turn out up to 500,000 pairs of trainers a year, should cut that to a week or less.

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It has been more than a decade since the Concorde was retired from service, and since then no passenger aircraft has exceeded the speed of sound. That might change in the not-too-distant future, thanks to a project from NASA and industry partner Lockheed Martin Corporation. The agency is close to testing its design for Quiet Supersonic Transport, or QueSST, which could lead to passenger jets that can again reach supersonic speeds.

The Concorde was never seen as a major commercial success — more of a vanity project for the few European airlines that operated the planes. The nature of supersonic flight meant the sonic boom at ground level could shatter windows. Thus, the plane could only fly at high speeds over the ocean. The trip between Europe and New York was fast, but other routes were not feasible. When the travel industry took a downturn in 2003, the Concorde was mothballed.

QueSST technology has the potential to make supersonic air travel workable even over land, and NASA has announced that its preliminary design review is done. The aim is to build a plane that can fly at supersonic speeds without the disruptive sonic boom. NASA, with the help of Lockheed Martin, has designed and tested a scale model version of the so-called Low Boom Flight Demonstration (LBFD) experimental aircraft, known as an X-plane. This model was placed in a 6-by-8-foot supersonic wind tunnel at NASA’s Glenn Research Center. This led engineers to confirm the fuselage, wing, and engine design could allow for quieter supersonic flight.

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Rudrapur, Uttrakhand, India — July 02, 2017

Revita Life Sciences, (http://revitalife.co.in) a biotechnology company focused on translational regenerative therapeutic applications, has announced that it is continuing to advance their novel, multi-modality clinical intervention in the state of brain death in humans.

“We have proactively continued to advance our multi-modality protocol, as an extended treatment before extubation, in an attempt to reverse the state of brain death” said Mr.Pranjal Agrawal, CEO Revita Life Sciences. “This treatment approach has yielded some very encouraging initial outcome signs, ranging from minor observations on blood pressure changes with response to painful stimuli, to eye opening and finger movements, with corresponding transient to permanent reversal changes in EEG patterns.”

This first exploratory study, entitled “Non-randomized, Open-labelled, Interventional, Single Group, and Proof of Concept Study with Multi-modality Approach in Cases of Brain Death Due to Traumatic Brain Injury Having Diffuse Axonal Injury” is ongoing at Anupam Hospital, Rudrapur, Uttrakhand. The intervention primarily involves intrathecal administration of minimal manipulated (processed at point of care) autologous stem cells derived from patient’s fat and bone marrow twice a week.

This study was inappropriately removed from the Indian Council of Medical Research (ICMR) database. ICMR has no regulatory oversight on such research in India.

The Central Drugs Standard Control Organization (CDSCO), Drug Controller General of India, had no objection to the program progressing. Regulatory approval as needed for new drugs, is currently not required when research is conducted on the recently deceased, although IRB and family consent is definitely required. CDSCO, the regulator of such studies, clearly states that “no regulatory requirements are needed for any study with minimal manipulated autologous stem cells in brain death subjects”.

Death is defined as the termination of all biological functions that sustain a living organism. Brain death, the complete and irreversible loss of brain function (including involuntary activity necessary to sustain life) as defined in the 1968 report of the Ad Hoc Committee of the Harvard Medical School, is the legal definition of human death in most countries around the world. Either directly through trauma, or indirectly through secondary disease indications, brain death is the final pathological state that over 60 million people globally transfer through each year.

“We are in process of publishing our initial retrospective results, as well ongoing early results, in a peer reviewed journal. These initial findings will prove invaluable to the future evolution of the program, as well as in progressing the development multi-modality regenerative therapeutics for the full range of the severe disorders of consciousness, including coma, PVS, the minimally conscious state, and a range of other degenerative CNS conditions in humans,” said Dr. Himanshu Bansal, Chief Scientific Officer, Revita Life Sciences and Director of Mother Cell.

With the maturation of the tools of medical science in the 21st century, especially cell therapies and regenerative medicines, tissues once considered irretrievable, may finally be able to be revived or rejuvenated. Hence many scientists believe that brain death, as presently defined, may one day be reversed. While the very long term goal is to find a solution for “re-infusing life”, the short term purpose of these types of studies is much less dramatic, which is to confirm if the current definition of brain irreversibility still holds true. There have been many anecdotal reports of brain death reversal across the world over the past decades in the scientific literature. Studies of this nature serve to verify and establish this very fact in a scientific and controlled manner. It will also one day give a fair chance to individuals, who are declared brain dead, especially after trauma.

About Revita Life Sciences

Revita Life Sciences is a biotechnology company focused on the development of stem cell therapies and regenerative medicine interventions that target areas of significant unmet medical need. Revita is led by Dr. Himanshu Bansal MD, who has spent over two decades developing novel MRI based classifications of spinal cord injuries as well as comprehensive treatment protocols with autologous tissues including bone marrow stem cells, Dural nerve grafts, nasal olfactory tissues, and omental transposition.

Often one hears others saying they want to work to live, not live to work. Do you agree? If so, try reading this. It might give you food for thought.

There’s this thing people say about work. I’m sure you’ve heard it countless times, and maybe you’ve said it yourself. I’ve heard it a lot too, and I’ve nodded at it more than once. As an expression, it may well be old enough to qualify as common wisdom.

“I want to work to live, not live to work.”

It sounds perfectly reasonable, or at least it does until you start thinking about it. The sentence above suggests three things.

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“The point is that wearables, bionics, AI, virtual/mixed/augmented reality – all bleeding edge technologies that (literally) are reshaping how we work, interact, learn, and live – are doing so as ‘other’ to our individual, biological selves.”

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Here are a few early summer ruminations to think about when looking at that beautiful night sky in the Northern Hemisphere. For brevity, I have omitted many aspects of these issues but I hope this will provide a spoonful or two of dessert for your gray matter. Chris Bakley was kind enough to allow me to use a couple of his photos.

A few intractable questions to think about after looking up into that big night sky.

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