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Envisioning an animal-free drug supply, scientists have — for the first time — reprogrammed a common bacterium to make a designer polysaccharide molecule used in pharmaceuticals and nutraceuticals. Published on March 22021, in Nature Communications, the researchers modified E. coli to produce chondroitin sulfate, a drug best known as a dietary supplement to treat arthritis that is currently sourced from cow trachea.

Genetically engineered E. coli is used to make a long list of medicinal proteins, but it took years to coax the bacteria into producing even the simplest in this class of linked sugar molecules — called sulfated glycosaminoglycans — that are often used as drugs and nutraceuticals…

“It’s a challenge to engineer E. coli to produce these molecules, and we had to make many changes and balance those changes so that the bacteria will grow well,” said Mattheos Koffas, lead researcher and a professor of chemical and biological engineering at Rensselaer Polytechnic Institute. “But this work shows that it is possible to produce these polysaccharides using E. coli in animal-free fashion, and the procedure can be extended to produce other sulfated glycosaminoglycans.”

Columbia researchers engineer first technique to exploit the tunable symmetry of 2D materials for nonlinear optical applications, including laser, optical spectroscopy, imaging, and metrology systems, as well as next-generation optical quantum information processing and computing.

Nonlinear optics, a study of how light interacts with matter, is critical to many photonic applications, from the green laser pointers we’re all familiar with to intense broadband (white) light sources for quantum photonics that enable optical quantum computing, super-resolution imaging, optical sensing and ranging, and more. Through nonlinear optics, researchers are discovering new ways to use light, from getting a closer look at ultrafast processes in physics, biology, and chemistry to enhancing communication and navigation, solar energy harvesting, medical testing, and cybersecurity.

Columbia Engineering researchers report that they developed a new, efficient way to modulate and enhance an important type of nonlinear optical process: optical second harmonic generation — where two input photons are combined in the material to produce one photon with twice the energy — from hexagonal boron nitride through micromechanical rotation and multilayer stacking. The study was published online on March 32021, by Science Advances.

University of Chicago, Argonne scientists tame photon-magnon interactions In a first-of-its-kind discovery, researchers in the University of Chicago’s Pritzker School of Molecular Engineering and Argonne National Laboratory announced they can directly control the interactions between two types of q.

The colorful community was built in just 13 weeks!


A colorful village of 40 tiny homes opened up in Los Angeles earlier this month. While each 64-foot square unit can only hold one to two people, the project as a whole is a huge step forward when it comes to solving one of the city’s biggest crises: homelessness.

The Chandler Boulevard Bridge Home Village, as it is officially named, was designed and built in just 13 weeks by Lehrer Architects and the city’s Bureau of Engineering, according to a press release. Located in North Hollywood, it is Los Angeles’s latest effort in providing shelter to its homeless population. It is managed by the Hope of the Valley Rescue Mission and is currently filled to capacity since its February 2 opening.

National Academies study says fusion can help decarbonize US energy, calls for public-private approach to pilot plant operation by 2035–40.

Electricity generated by fusion power plants could play an important role in decarbonizing the U.S. energy sector by mid-century, says a new consensus study report from the National Academies of Sciences, Engineering, and Medicine, which also lays out for the first time a set of technical, economic, and regulatory standards and a timeline for a U.S. fusion pilot plant that would begin producing energy in the 2035–40 time frame.

To achieve this key step toward commercialization, the report calls for an aggressive public-private effort to produce by 2028 a pilot plant design that can, when built, accommodate any of the developmental approaches seeking to realize fusion’s potential as a safe, carbon-free, on-demand energy source.

Engineers at the University of California San Diego have developed a soft, stretchy skin patch that can be worn on the neck to continuously track blood pressure and heart rate while measuring the wearer’s levels of glucose as well as lactate, alcohol, or caffeine. It is the first wearable device that monitors cardiovascular signals and multiple biochemical levels in the human body at the same time.

“This type of wearable would be very helpful for people with underlying medical conditions to monitor their own health on a regular basis,” said Lu Yin, a nanoengineering Ph.D. student at UC San Diego and co-first author of the study published on February 152021, in Nature Biomedical Engineering. “It would also serve as a great tool for remote patient monitoring, especially during the COVID-19 pandemic when people are minimizing in-person visits to the clinic.”

Such a device could benefit individuals managing high blood pressure and diabetes — individuals who are also at high risk of becoming seriously ill with COVID-19. It could also be used to detect the onset of sepsis, which is characterized by a sudden drop in blood pressure accompanied by a rapid rise in lactate level.

Researchers unlocked the electronic properties of graphene by folding the material like origami paper.


Researchers at Monash University’s Department of Chemical Engineering, IITB-Monash Research Academy Mumbai, and The Indian Institute of Technology’s Department of Chemical Engineering have used reactive flash volatilisation (RFV) gasification technology to produce hydrogen using microalgae, giving rise to newer and cleaner forms of energy.

“” This type of wearable would be very helpful for people with underlying medical conditions to monitor their own health on a regular basis,” co-first author of the study Lu Yin said in a news release.

New wearable device converts body heat into electricity.
“It would also serve as a great tool for remote patient monitoring, especially during the COVID-19 pandemic when people are minimizing in-person visits to the clinic,” Yin, a nano-engineering doctoral student at the University of California, San Diego.

In addition to monitoring chronic conditions like diabetes and high blood pressure, as well as pinpointing the onset of sepsis, the patch could help predict people at risk of becoming severely ill with COVID-19.


Scientists have developed a thin, flexible skin patch, worn on the neck, that can provide all-in-one health monitoring capabilities, including the wearer’s heart rate, blood pressure and glucose levels.

Is the Minister of Science, Technology and Telecommunications for the country of Costa Rica and has served in this role since June 1st, 2020.

Dr. Vega-Castillo was previously Deputy Minister of Science and Technology and also served as Vice President for Research and Outreach in the Instituto Tecnológico de Costa Rica (ITCR) where she promoted the strengthening of research and outreach, and linkages with the national and international sector for increasing the scientific publication and patents.

Dr. Vega-Castillo has a degree in Electronic Engineering from the ITCR and graduated with a PhD. in Microelectronics and Microsystems at Technische Universität Hamburg-Harburg (TUHH).

We discuss the Costa-Rica National Bio-Economy Strategy — An initiative that has a knowledge-based, green, resilient, and competitive economy as its model and which also proposes the application of the principles of a circular bio-economy and the de-carbonization of production and consumption processes.