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According to the Mayo Clinic, the Nerve regeneration is a complex process, because of its complexity, regrowth of nerves after injury or disease is extremely rare. Nerve damages more often than not are incurable and cause permanent disability, but now the scientist has proved that Advanced 3D printing methods could hold a possible cure for such patients.

To prove the proof of concept, a physically disabled rat was chosen as a test subject. The scientist used a specially designed 3D scanners and 3D Printers to create a custom silicone guide, 3D-printed chemical cues were added to the guide to promote both motor and sensory nerve regeneration. This was then implanted into the rat with surgically grafting it to the cut ends of the nerve. The operation was a extremely successful and the rat showed tremendous improvement in the way it walked within 10 to 12 weeks.

The Lead researcher of this medical breakthrough, Michael McAlpine, a mechanical engineering professor from the University of Minnesota said “This represents an important proof of concept of the 3D printing of custom nerve guides for the regeneration of complex nerve injuries,”

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Researchers from the University of South Florida College of Engineering have proposed a new form of computing that uses circular nanomagnets to solve quadratic optimization problems orders of magnitude faster than that of a conventional computer.

A wide range of application domains can be potentially accelerated through this research such as finding patterns in social media, error-correcting codes to Big Data and biosciences.

In an article published in the current issue of Nature Nanotechnology, “Non Boolean computing with nanomagnets for computer vision applications,” authors Sanjukta Bhanja, D.K. Karunaratne, Ravi Panchumarthy, Srinath Rajaram, and Sudeep Sarkar discuss how their work harnessed the energy-minimization nature of nanomagnetic systems to solve the quadratic optimization problems that arise in computer vision applications, which are computationally expensive.

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Can black phosphorous rival #graphene?


A new experimental revelation about black phosphorus nanoribbons should facilitate the future application of this highly promising material to electronic, optoelectronic and thermoelectric devices. A team of researchers at the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab) has experimentally confirmed strong in-plane anisotropy in thermal conductivity, up to a factor of two, along the zigzag and armchair directions of single-crystal black phosphorous nanoribbons.

“Imagine the lattice of black phosphorous as a two-dimensional network of balls connected with springs, in which the network is softer along one direction of the plane than another,” says Junqiao Wu, a physicist who holds joint appointments with Berkeley Lab’s Materials Sciences Division and the University of California (UC) Berkeley’s Department of Materials Science and Engineering. “Our study shows that in a similar manner heat flow in the black phosphorous nanoribbons can be very different along different directions in the plane. This thermal conductivity has been predicted recently for 2D black phosphorous crystals by theorists but never before observed.”

Wu is the corresponding author of a paper describing this research in Nature Communications titled “Anisotropic in-plane thermal conductivity of black phosphorus nanoribbons at temperatures higher than 100K.” The lead authors are Sangwook Lee and Fan Yang. (See below for a complete list of authors)

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Coronary artery structure being 3-D bioprinted (credit: Carnegie Mellon University College of Engineering)

Carnegie Mellon scientists are creating cutting-edge technology that could one day solve the shortage of heart transplants, which are currently needed to repair damaged organs.

“We’ve been able to take MRI images of coronary arteries and 3-D images of embryonic hearts and 3-D bioprint them with unprecedented resolution and quality out of very soft materials like collagens, alginates and fibrins,” said Adam Feinberg, an associate professor of Materials Science and Engineering and Biomedical Engineering at Carnegie Mellon University.

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As of this month, over 4,000 Americans are on the waiting list to receive a heart transplant. With failing hearts, these patients have no other options; heart tissue, unlike other parts of the body, is unable to heal itself once it is damaged. Fortunately, recent work by a group at Carnegie Mellon could one day lead to a world in which transplants are no longer necessary to repair damaged organs.

“We’ve been able to take MRI images of coronary arteries and 3-D images of embryonic hearts and 3-D bioprint them with unprecedented resolution and quality out of very like collagens, alginates and fibrins,” said Adam Feinberg, an associate professor of Materials Science and Engineering and Biomedical Engineering at Carnegie Mellon University. Feinberg leads the Regenerative Biomaterials and Therapeutics Group, and the group’s study was published in the October 23 issue of the journal Science Advances. A demonstration of the technology can be seen below.

“As excellently demonstrated by Professor Feinberg’s work in bioprinting, our CMU researchers continue to develop novel solutions like this for problems that can have a transformational effect on society,” said Jim Garrett, Dean of Carnegie Mellon’s College of Engineering. “We should expect to see 3-D bioprinting continue to grow as an important tool for a large number of medical applications.”

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How cool is this!


Rendering of a virus used in the MIT experiments. The light-collecting centers, called chromophores, are in red, and chromophores that just absorbed a photon of light are glowing white. After the virus is modified to adjust the spacing between the chromophores, energy can jump from one set of chromophores to the next faster and more efficiently. (credit: the researchers and Lauren Alexa Kaye)

MIT engineers have achieved a significant efficiency boost in a light-harvesting system, using genetically engineered viruses to achieve higher efficiency in transporting energy from receptors to reaction centers where it can be harnessed, making use of the exotic effects of quantum mechanics. Emulating photosynthesis in nature, it could lead to inexpensive and efficient solar cells or light-driven catalysis,

This achievement in coupling quantum research and genetic manipulation, described this week in the journal Nature Materials, was the work of MIT professors Angela Belcher, an expert on engineering viruses to carry out energy-related tasks, and Seth Lloyd, an expert on quantum theory and its potential applications, and 15 collaborators at MIT and in Italy.

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If you think the image above looks frightening, you’re right. The crazy contraption pictured in the image is the first portable railgun, a futuristic projectile launcher associated most commonly with the military or NASA. The man in the image above isn’t in the military, and he’s not a NASA engineer. Instead, he’s a civilian who used some engineering smarts, some widely available parts and a 3D printer to create a functioning weapon that can fire graphite, aluminum, tungsten and even plasma projectiles at speeds of more than 560 mph.

And then there’s the best part: There are videos of this homemade railgun in action.

MUST READ: The iPhone I couldn’t live with

Little is known about Imgur user “NSA_Listbot” beyond the fact that he’s just short of being a wizard with AutoCAD and a 3D printer. The man took to Imgur over the weekend to share what may very well be one of the most amazing and terrifying DIY projects that has even been attempted. And he didn’t just attempt it, he built it.

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A team from Stanford University might have made a breakthrough that could change the lives of people with missing limbs. Researchers have developed an artificial substitute for skin that is capable of sensing when it is being touched and sending that data to the nervous system. It’s hoped that technology like this could be used to build futuristic prostheses that could be wired into the nervous systems of amputees. In addition, not only will these people be able to know if they’re touching something, they’ll also know how much pressure is being used.

Put very simply, the skin is comprised of two layers of rubbery plastic skin with a flexible circuit printed on, courtesy of the folks at Xerox Parc. Sandwiched between the two is a run of carbon nanotubes, which conduct electricity when they’re pushed closer together. The harder the compression, the more current passes between them, which is how the skin can understand differences in pressure.

That, however, isn’t enough, since that data would still have to be transmitted somehow into the user’s brain. In the end, the team opted to harness a field of science called optogenetics, which involves genetically-engineering cells so that they react to specific frequencies of light. By creating optogenetic neurons that are capable of sensing light patterns, the team proved that it’s possible to make this technology work in a person.

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My take on the MIT study.


Routine human missions to Mars would be much more efficient if they first swung by Earth’s Moon to pick up fuel for the trip, a new MIT strategic engineering study concludes. NASA’s 90’s-era mantra of “Back to the Moon and on to Mars” really does make sense, a new paper published in the Journal of Spacecraft and Rockets notes.

The idea is that a crewed mission to Mars would greatly save on fuel and launch costs if it first made an interplanetary pit stop at a space-based depot to pick up its needed fuel. In this case, such a depot would optimally be placed at the Earth-Moon Lagrange Point 2 (EML2), a point of gravitational equilibrium lying beyond the Moon’s far side.

The paper’s authors conclude that such a stop would reduce the mission’s initial launch mass into low earth orbit by as much as 68%.

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