Fan speeds clock in over 11000 RPM.
Dynatron rolls out the A38, a robust CPU air cooler for AMD Ryzen Threadripper and EPYC processors.
Category: computing
Researchers at Chalmers University of Technology, Gothenburg, Sweden, have developed a novel type of thermometer that can simply and quickly measure temperatures during quantum calculations with extremely high accuracy. The breakthrough provides a benchmarking tool for quantum computing of great value—and opens up for experiments in the exciting field of quantum thermodynamics.
Key components in quantum computers are coaxial cables and waveguides—structures that guide waveforms and act as the vital connection between the quantum processor and the classical electronics that control it. Microwave pulses travel along the waveguides to the quantum processor, and are cooled down to extremely low temperatures along the way. The waveguide also attenuates and filters the pulses, enabling the extremely sensitive quantum computer to work with stable quantum states.
In order to maximize control over this mechanism, the researchers need to be sure that these waveguides are not carrying noise due to thermal motion of electrons on top of the pulses that they send. In other words, they have to measure the temperature of the electromagnetic fields at the cold end of the microwave waveguides, the point where the controlling pulses are delivered to the computer’s qubits. Working at the lowest possible temperature minimizes the risk of introducing errors in the qubits.
Big Blue has made Qiskit Metal generally available, to let “anyone” try their hand at quantum hardware design.
Pioneering experiment could help design energy-efficient materials.
In a groundbreaking study published in Physical Review Research, a group of University of Chicago scientists announced they were able to turn IBM’s largest quantum computer into a quantum material itself.
They programmed the computer such that it turned into a type of quantum material called an exciton condensate, which has only recently been shown to exist. Such condensates have been identified for their potential in future technology, because they can conduct energy with almost zero loss.
Long but annotated! Most important here is human data for specific treatments due out starting in May or June. And apparently they had a mouse study where they expected a paper due out already but other groups chimed in to help with more testing so there is a delay.
Liz Parrish, CEO of BioViva Science and patient zero of biological rejuvenation with gene therapies, is interviewed by Zora Benhamou on her fresh podcast “HackMyAge”.
During the conversation, Liz enters deep into the world of gene therapies, either to cure monogenic diseases, multifactorial genetic diseases, or the mother of all diseases: aging itself.
The conversation lasts for one hour and twenty minutes and has no waste. However, to go direct to certain themes use the following time marks:
0:00:00 Zora introduces the podcast: who is Liz Parrish and what the conversation will be about.
0:02:17 Liz Parrish begins her intervention in the podcast.
0:03:00 What is gene therapy and how Liz got involved in gene therapy applied to aging.
0:05:52 How Liz and her son are dealing with the treatment of type 1 diabetes.
0:08:05 How Liz got involved in becoming the first human treated with gene therapy to treat biological aging and what it means to go through gene therapy.
0:14:34 Current legal status of gene therapies and ways to get the treatment.
0:16:20 Current costs of undergoing gene therapies.
0:18:49 Why aren’t medical doctors applying gene therapies more than they actually are and what’s the role of medical tourism.
0:21:34 What prompted Liz to become the first patient to undergo gene therapy for biological aging.
0:25:25 How gene therapies compare with nutraceuticals and pharmaceuticals.
0:30:05 Why big pharmaceutical companies haven’t jumped into the field with more impetus.
0:33:20 How long will it take for gene therapies to become mainstream.
0:39:29 How gene therapies work and what is the experience for the patient that goes through it.
0:48:11 What can be expected from treating sarcopenia with gene therapy.
0:50:02 Where do the genes used in gene therapies come from.
0:53:12 What can expect someone who is treated with gene therapy to tackle dementia.
0:54:34 What are the major changes experienced by Liz in her blood markers since being treated.
0:56:38 When and how did Liz go through her gene therapies, not only for hTERT and Follistatin but also for Klotho and PGC-1alpha. What are the latter two all about?
1:02:15 How Liz envision the future of humans.
1:04:08 Liz comments on a coming paper BioViva is working together with Rutgers University.
1:05:38 Other studies in the pipeline.
1:06:45 Explanation of testing services and data storage offered by BioViva.
1:17:20 Liz on topical creams and/or small molecules for removal of senescent cells, and pills for telomeres lengthening.
1:19:16 Liz responds to “if you could meet your 20-year-old self what would you tell her”
1:20:03 What can people do to help Liz on her mission.
1:22:12 Resources to learn more about the future that is coming, genomics and gene therapy technology.
1:24:18 BioViva and Integrated Health Systems websites as well as social media sites where Liz and BioViva are actively present.
1:25:38 Words of farewell.
Websites:
HackMyAge: https://hackmyage.com/
BioViva Science: https://bioviva-science.com/
Integrated Health Systems: https://www.integrated-health-systems.com/
By Chuck Brooks
The world of computing has witnessed seismic advancements since the invention of the electronic calculator in the 1960s. The past few years in information processing have been especially transformational. What were once thought of as science fiction fantasies are now technological realties. Classical computing has become more exponentially faster and more capable and our enabling devices smaller and more adaptable.
The Research Group on Synthetic Biology for Biomedical Applications at Pompeu Fabra University in Barcelona, Spain, has designed a cellular device capable of computing by printing cells on paper. For the first time, they have developed a living device that could be used outside the laboratory without a specialist, and it could be produced on an industrial scale at low cost. The study is published in Nature Communications and was carried out by Sira Mogas-Díez, Eva Gonzalez-Flo and Javier Macía.
We currently have many electronic devices available to us such as computers and tablets whose computing power is highly efficient. But, despite their power, they are very limited devices for detecting biological markers, such as those that indicate the presence of a disease. For this reason, a few years ago ‘biological computers’ began to be developed—in other words, living cellular devices that can detect multiple markers and generate complex responses. In them, the researchers leverage biological receptors that allow detecting exogenous signals and, by means of synthetic biology, modify them to emit a response in accordance with the information they detect.
So far, cellular devices have been developed that must operate in the laboratory, for a limited time, under specific conditions, and must be handled by a specialist in molecular biology. Now, a team of researchers from Pompeu Fabra University has developed new technology to ‘print’ cellular devices on paper that can be used outside the laboratory.
Efficacy of the radial pair potential approximation for molecular dynamics simulations of dense plasmas
Posted in computing, information science, nuclear energy, particle physics | Leave a Comment on Efficacy of the radial pair potential approximation for molecular dynamics simulations of dense plasmas
In this work, we carry out KS-MD simulations for a range of elements, temperatures, and densities, allowing for a systematic comparison of three RPP models. While multiple RPP models can be selected, 7–11 7. J. Vorberger and D. Gericke, “Effective ion–ion potentials in warm dense matter,” High Energy Density Phys. 9, 178 (2013). https://doi.org/10.1016/j.hedp.2012.12.009 8. Y. Hou, J. Dai, D. Kang, W. Ma, and J. Yuan, “Equations of state and transport properties of mixtures in the warm dense regime,” Phys. Plasmas 22, 022711 (2015). https://doi.org/10.1063/1.4913424 9. K. Wünsch, J. Vorberger, and D. Gericke, “Ion structure in warm dense matter: Benchmarking solutions of hypernetted-chain equations by first-principle simulations,” Phys. Rev. E 79, 010201 (2009). https://doi.org/10.1103/PhysRevE.79.010201 10. L. Stanton and M. Murillo, “Unified description of linear screening in dense plasmas,” Phys. Rev. E 91, 033104 (2015). https://doi.org/10.1103/PhysRevE.91.033104 11. W. Wilson, L. Haggmark, and J. Biersack, “Calculations of nuclear stopping, ranges, and straggling in the low-energy region,” Phys. Rev. B 15, 2458 (1977). https://doi.org/10.1103/PhysRevB.15.2458 we choose to compare the widely used Yukawa potential, which accounts for screening by linearly perturbing around a uniform density in the long-wavelength (Thomas–Fermi) limit, a potential constructed from a neutral pseudo-atom (NPA) approach, 12–15 12. L. Harbour, M. Dharma-wardana, D. D. Klug, and L. J. Lewis, “Pair potentials for warm dense matter and their application to x-ray Thomson scattering in aluminum and beryllium,” Phys. Rev. E 94, 053211 (2016). https://doi.org/10.1103/PhysRevE.94.053211 13. M. Dharma-wardana, “Electron-ion and ion-ion potentials for modeling warm dense matter: Applications to laser-heated or shock-compressed Al and Si,” Phys. Rev. E 86, 036407 (2012). https://doi.org/10.1103/PhysRevE.86.036407 14. F. Perrot and M. Dharma-Wardana, “Equation of state and transport properties of an interacting multispecies plasma: Application to a multiply ionized al plasma,” Phys. Rev. E 52, 5352 (1995). https://doi.org/10.1103/PhysRevE.52.5352 15. L. Harbour, G. Förster, M. Dharma-wardana, and L. J. Lewis, “Ion-ion dynamic structure factor, acoustic modes, and equation of state of two-temperature warm dense aluminum,” Phys. Rev. E 97, 043210 (2018). https://doi.org/10.1103/PhysRevE.97.043210 and the optimal force-matched RPP that is constructed directly from KS-MD simulation data.
Each of the models we chose impacts our physics understanding and has clear computational consequences. For example, success of the Yukawa model reveals the insensitivity to choices in the pseudopotential and screening function and allows for the largest-scale simulations. Large improvements are expected from the NPA model, which makes many fewer assumptions with a modest cost of pre-computing and tabulating forces. (See the Appendix for more details on the NPA model.) The force-matched RPP requires KS-MD data and is therefore the most expensive to produce, but it reveals the limitations of RPPs themselves since they are by definition the optimal RPP.
Using multiple metrics of comparison between RPP-MD and KS-MD including the relative force error, ion–ion equilibrium radial distribution function g (r), Einstein frequency, power spectrum, and the self-diffusion transport coefficient, the accuracy of each RPP model is analyzed. By simulating disparate elements, namely, an alkali metal, multiple transition metals, a halogen, a nonmetal, and a noble gas, we see that force-matched RPPs are valid for simulating dense plasmas at temperatures above fractions of an eV and beyond. We find that for all cases except for low temperature carbon, force-matched RPPs accurately describe the results obtained from KS-MD to within a few percent. By contrast, the Yukawa model appears to systematically fail at describing results from KS-MD at low temperatures for the conditions studied here validating the need for alternate models such as force-matching and NPA approaches at these conditions.
It’s another step on the road to developing quantum information processing applications: A key experiment succeeded in going beyond the previously defined limits for photon applications. Anahita Khodadad Kashi and Prof. Dr. Michael Kues from the Institute of Photonics and the Cluster of Excellence PhoenixD at Leibniz University Hannover (Germany) have demonstrated a novel interference effect. The scientists have thus shown that new color-coded photonic networks can be tapped, and the number of photons involved can be scaled. “This discovery could enable new benchmarks in quantum communication, computational operations of quantum computers as well as quantum measurement techniques and is feasible with existing optical telecommunication infrastructure,” says Kues.
The decisive experiment was successfully performed in the newly established Quantum Photonics Laboratory (QPL) of the Institute of Photonics and the Hannover Centre for Optical Technologies at Leibniz University Hannover. Anahita Khodadad Kashi succeeded in quantum-mechanically interfering independently generated pure photons with different colors, i.e., frequencies. Khodadad Kashi detected a so-called Hong-Ou-Mandel effect.
Hong-Ou-Mandel interference is a fundamental effect of quantum optics that forms the basis for many quantum information processing applications—from quantum computing to quantum metrology. The effect describes how two photons behave when they collide on a spatial beam splitter and explains the phenomenon of quantum mechanical interference.
All of which would be nice and handy, but clearly, privacy and ethics are going to be a big issue for people — particularly when a company like Facebook is behind it. Few people in the past would ever have lived a life so thoroughly examined, catalogued and analyzed by a third party. The opportunities for tailored advertising will be total, and so will the opportunities for bad-faith actors to abuse this treasure trove of minute detail about your life.
But this tech is coming down the barrel. It’s still a few years off, according to the FRL team. But as far as it is concerned, the technology and the experience are proven. They work, they’ll be awesome, and now it’s a matter of working out how to build them into a foolproof product for the mass market. So, why is FRL telling us about it now? Well, this could be the greatest leap in human-machine interaction since the touchscreen, and frankly Facebook doesn’t want to be seen to be making decisions about this kind of thing behind closed doors.
“I want to address why we’re sharing this research,” said Sean Keller, FRL Director of Research. “Today, we want to open up an important discussion with the public about how to build these technologies responsibly. The reality is that we can’t anticipate or solve all the ethical issues associated with this technology on our own. What we can do is recognize when the technology has advanced beyond what people know is possible and make sure that the information is shared openly. We want to be transparent about what we’re working on, so people can tell us their concerns about this technology.””
When augmented reality hits the market at full strength, putting digital overlays over the physical world through transparent glasses, it will intertwine itself deeper into the fabric of your life than any technology that’s come before it. AR devices will see the world through your eyes, constantly connected, always trying to figure out what you’re up to and looking for ways to make themselves useful.
Facebook is already leaps and bounds ahead of the VR game with its groundbreaking Oculus Quest 2 wireless headsets, and it’s got serious ambitions in the augmented reality space too. In an online “Road to AR glasses” roundtable for global media, the Facebook Reality Labs (FRL) team laid out some of the eye-popping next-gen AR technology it’s got up and running on the test bench. It also called on the public to get involved in the discussion around privacy and ethics, with these devices just a few scant years away from changing our world as completely as the smartphone did.
Wrist-mounted neuro-motor interfaces
Presently, our physical interactions with digital devices are crude, and they frequently bottleneck our progress. The computer mouse, the graphical user interface, the desktop metaphor and the touchscreen have all been great leaps forward, but world-changing breakthroughs in human-machine interface (HMI) technology come along once in a blue moon.