Applications are now open for the role of ESA-sponsored research medical doctor at Concordia research station in Antarctica for the 2023 winter over season. Do you have a medical degree, an interest in space exploration and the fortitude to spend almost a year in isolation in the world’s largest desert? Apply today for this unique post.
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Located at the mountain plateau called Dome C in Antarctica, the French-Italian base is one of only three that is inhabited all year long.
The preliminary assessment says the variant’s mutations could make it more transmissible and better able to evade the body’s immune defenses, but many questions remain.
The variant’s emergence in South Africa has driven a sharp increase in hospitalizations in Gauteng province during the past two weeks, although fewer patients than in previous surges are being treated for severe disease.
Kind of starts out with a no but ends in a yes. Just a few minutes long.
An increasing number of studies suggest the presence of a “metabolic clock” that controls aging. This clock involves the accumulation of metabolic alterations and a decline in metabolic homeostasis and biological fitness. There are nine cellular hallmarks of aging: telomere attrition, genomic instability, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, loss of proteostasis, deregulated nutrient sensing, epigenetic alterations, and altered intercellular communication. Metabolic alterations have been implicated in each of these processes.
https://www.cell.com/fulltext/S0092-8674(13)00645-4
https://www.cell.com/cell/pdf/S0092-8674(16)30981-3.pdf.
David Sinclair is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School, where he and his colleagues study sirtuins—protein-modifying enzymes that respond to changing NAD+ levels and to caloric restriction—as well as chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, cancer, and cellular reprogramming.
Dr David Sinclair has suggested that aging is a disease—and that we may soon have the tools to put it into remission—and he has called for greater international attention to the social, economic and political and benefits of a world in which billions of people can live much longer and much healthier lives.
Dr David Sinclair is the co-founder of several biotechnology companies (Life Biosciences, Sirtris, Genocea, Cohbar, MetroBiotech, ArcBio, Liberty Biosecurity) and is on the boards of several others.
He is also co-founder and co-chief editor of the journal Aging. He is an inventor on 35 patents and has received more than 35 awards and honors. In 2014, he was on Time Magazine’s list of the “100 Most Influential People in the World,” and listed as Time’s Top 50 in healthcare in 2018.
DISCLAIMER: Please note that none of the information in this video constitutes health advice or should be substituted in lieu of professional guidance. The video content is purely for informational purposes.
#DavidSinclair #ReverseAging #Epigenetic #OleicAcid#NMN #NAD #Sirtuins #Fasting #Exercise #NMN #NADIV #Longevity #RestoreYouth #Reprogramming #DavidSinclair #DrSinclairLab #Lifespan #Healthspan #Younger #Resveratrol #antiaging #DrSinclair #NAD #longevity #Bioscience #Epigenome #AndrewHuberman
An ink made using engineered bacterial cells can be 3D-printed into structures that release anti-cancer drugs or capture toxins from the environment.
The microbial ink is the first printable gel to be made entirely from proteins produced by E.coli cells, without the addition of other polymers.
“This is the first of its kind… a living ink that can respond to the environment. We have repurposed the matrix that these bacteria normally utilise as a shielding material to form a bio-ink,” says Avinash Manjula-Basavanna at the Massachusetts Institute of Technology in Boston.
Urban Aeronautics, the Israel-based aerospace company behind the world’s first compact, wingless electric vertical takeoff, and landing (eVTOL) vehicle, is getting closer to turning its groundbreaking concept into reality. The company said it has raised the first $10 million of a $100 million funding round this week towards CityHawk from private investors in the US, Brazil, and Israel.
According to the company, the car-sized, six-seater CityHawk has more in common with birds than with nearly every other eVTOL prototype in existence. With a distinct, wingless exterior and patented fully-enclosed Fancraft rotor system, the CityHawk is mainly designed for commercial air charters and emergency medical services (EMS). It will be fueled by hydrogen, the most sustainable technology in development today. This means it must be able to conduct multiple trips within a city per day with zero emissions and minimal noise.
An innovative Fancraft technology is based on dual enclosed, ducted rotors with a variable pitch for thrust control, which enable uncompromised stability even in strong winds and turbulence during takeoff, hovering, and landing. The enclosed structure also results in minimal noise, both inside the cabin and outside.
Posted in biotech/medical, neuroscience, robotics/AI | Leave a Comment on Brain scientists unveil wiring diagram containing 200,000 cells and nearly half billion connections in tiny piece of a mouse’s brain
Detailed map captures 3D shapes of neurons and their synapses in stunning detail and is open to community for neuroscience and machine learning research July 29, 2021…
Several different mouse neurons virtually reconstructed in 3D show the complexity of tracing the shapes and branching axons and dendrites within a small piece of the brain.
A team of neuroscientists and engineers at the Allen Institute, Princeton University and Baylor College of Medicine has just released a collection of data that marries a 3D wiring diagram with the function of tens of thousands of neurons to create the most detailed examination of mammalian brain circuitry to date.
The dataset, which is publicly available for anyone in the community to browse and use, maps the fine structures and connectivity of 200,000 brain cells and close to 500 million synapses all contained in a cubic millimeter chunk of mouse brain — approximately the size of a grain of sand — from the visual neocortex, the part of the mammalian brain that processes what we see.
“Sunday Morning” anchor Jane Pauley hosts “Forever Young: Searching for the Fountain of Youth,” a one-hour primetime special exploring the wonders, rewards, and challenges of growing older, to air on CBS Sunday, November 28 at 10 p.m. ET/PT, and to stream on Paramount+.
Can we reset our biological clocks? | Watch Video Life expectancy has increased in recent decades, but researchers are looking for ways to further slow the aging process. Correspondent Lee Cowan looks into recent developments in the study of extending human life, and efforts to ward off disease by targeting the biology of aging itself.
“It is not known at this time whether the variant is more transmissible, or more dangerous to the health of those who catch it, than other coronavirus variants.”
There are two confirmed cases of the omicron variant of the coronavirus in Ottawa, the Ontario government announced Sunday.
“Today, the province of Ontario has confirmed two cases of the omicron variant of COVID-19 in Ottawa, both of which were reported in individuals with recent travel from Nigeria. Ottawa Public Health is conducting case and contact management and the patients are in isolation,” the statement said.
Cockroach farming is practiced in China on a massive scale. At present, there are hundreds of cockroach farms in China, with the total number of cockroaches produced annually exceeding the global human population. The insects produced in these unique farms are mostly used in the production of cosmetics and medicines, or for animal feed.
In 2018, Chinese pharmaceutical company Gooddoctor claims that it has earned US$684 million in revenue through selling a “healing potion” made from cockroaches that is used annually by thousands of hospitals and millions of Chinese patients to treat respiratory, gastric, and other diseases.
However, the use of cockroaches in China is not just limited to the pharmaceutical and beauty industries. The protein-rich insects are also processed and fed as an organic meal to poultry farm animals, used to deal with food waste, and are often served in special recipes in some Chinese restaurants.
Several different mouse neurons virtually reconstructed in 3D show the complexity of tracing the shapes and branching axons and dendrites within a small piece of the brain.