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๐™€๐™ซ๐™ค๐™ก๐™ช๐™ฉ๐™ž๐™ค๐™ฃ๐™–๐™ง๐™ฎ ๐™—๐™ž๐™ค๐™ก๐™ค๐™œ๐™ž๐™จ๐™ฉ๐™จ ๐™๐™–๐™ซ๐™š ๐™ฉ๐™ง๐™ค๐™ช๐™—๐™ก๐™š ๐™š๐™ญ๐™ฅ๐™ก๐™–๐™ž๐™ฃ๐™ž๐™ฃ๐™œ ๐™ฌ๐™๐™ฎ ๐™จ๐™˜๐™๐™ž๐™ฏ๐™ค๐™ฅ๐™๐™ง๐™š๐™ฃ๐™ž๐™– ๐™–๐™ฃ๐™™ ๐™—๐™ž๐™ฅ๐™ค๐™ก๐™–๐™ง ๐™™๐™ž๐™จ๐™ค๐™ง๐™™๐™š๐™ง โ€” ๐™ฌ๐™๐™ž๐™˜๐™ ๐™–๐™ง๐™š ๐™๐™ž๐™œ๐™๐™ก๐™ฎ ๐™๐™š๐™ง๐™ž๐™ฉ๐™–๐™—๐™ก๐™š ๐™˜๐™ค๐™ฃ๐™™๐™ž๐™ฉ๐™ž๐™ค๐™ฃ๐™จ โ€” ๐™ฅ๐™š๐™ง๐™จ๐™ž๐™จ๐™ฉ ๐™ž๐™ฃ ๐™ฅ๐™ค๐™ฅ๐™ช๐™ก๐™–๐™ฉ๐™ž๐™ค๐™ฃ๐™จ ๐™™๐™š๐™จ๐™ฅ๐™ž๐™ฉ๐™š ๐™๐™–๐™ง๐™ข๐™ž๐™ฃ๐™œ ๐™ง๐™š๐™ฅ๐™ง๐™ค๐™™๐™ช๐™˜๐™ฉ๐™ž๐™ซ๐™š ๐™›๐™ž๐™ฉ๐™ฃ๐™š๐™จ๐™จ.

๐™๐™š๐™จ๐™š๐™–๐™ง๐™˜๐™๐™š๐™ง๐™จ ๐™ข๐™–๐™ฎ ๐™๐™–๐™ซ๐™š ๐™›๐™ค๐™ช๐™ฃ๐™™ ๐™–๐™ฃ ๐™š๐™ญ๐™ฅ๐™ก๐™–๐™ฃ๐™–๐™ฉ๐™ž๐™ค๐™ฃ ๐™ž๐™ฃ ๐™ง๐™š๐™˜๐™š๐™ฃ๐™ฉ๐™ก๐™ฎ ๐™š๐™ซ๐™ค๐™ก๐™ซ๐™š๐™™ ๐™ง๐™š๐™œ๐™ž๐™ค๐™ฃ๐™จ ๐™ค๐™› ๐™ฉ๐™๐™š ๐™๐™ช๐™ข๐™–๐™ฃ ๐™œ๐™š๐™ฃ๐™ค๐™ข๐™š ๐™ฉ๐™๐™–๐™ฉ ๐™–๐™ง๐™š ๐™ฃ๐™ค๐™ฉ ๐™ช๐™จ๐™ช๐™–๐™ก๐™ก๐™ฎ ๐™ง๐™š๐™˜๐™ค๐™œ๐™ฃ๐™ž๐™ฏ๐™š๐™™ ๐™–๐™จ ๐™œ๐™š๐™ฃ๐™š๐™จ ๐™—๐™ช๐™ฉ ๐™˜๐™–๐™ฃ ๐™จ๐™ฉ๐™ž๐™ก๐™ก ๐™˜๐™ค๐™™๐™š ๐™›๐™ค๐™ง ๐™ฅ๐™ง๐™ค๐™ฉ๐™š๐™ž๐™ฃ๐™จ.

๐™๐™๐™ž๐™จ โ€œ๐™™๐™–๐™ง๐™  ๐™œ๐™š๐™ฃ๐™ค๐™ข๐™šโ€ ๐™ข๐™–๐™ฎ ๐™œ๐™š๐™ฃ๐™š๐™ง๐™–๐™ฉ๐™š ๐™ฅ๐™ง๐™ค๐™ฉ๐™š๐™ž๐™ฃ๐™จ ๐™ฉ๐™๐™–๐™ฉ ๐™–๐™ง๐™š ๐™ซ๐™ž๐™ฉ๐™–โ€ฆ See more.

The Neuro-Network.

๐‚๐ฅ๐ฎ๐ž๐ฌ ๐ญ๐จ ๐จ๐ซ๐ข๐ ๐ข๐ง๐ฌ ๐จ๐Ÿ ๐›๐ข๐ฉ๐จ๐ฅ๐š๐ซ ๐š๐ง๐ ๐ฌ๐œ๐ก๐ข๐ณ๐จ๐ฉ๐ก๐ซ๐ž๐ง๐ข๐š ๐Ÿ๐จ๐ฎ๐ง๐ ๐ข๐ง โ€˜๐๐š๐ซ๐ค ๐ ๐ž๐ง๐จ๐ฆ๐žโ€™


The authors of a recent study on the genetics of schizophrenia and bipolar disorder identify a potential role for the so-called dark genome.

Circa 2019


Want superhero powers that let you see in the dark just like your cat? In the near future you may be able toโ€”as long as youโ€™re not too squeamish to get injections right into your eyeballs.

Researchers from the University of Massachusetts Medical School have discovered a way to give mice the ability to see infrared light, a part of the visible spectrum that we humans simply cannot see, although itโ€™s there.

What we can see is called the visible spectrum. Itโ€™s the part of the electromagnetic spectrum that can be seen as light, but can also take other forms, like radio waves or ultraviolet light. Humans can see the wavelengths from 380 to 700 nanometers, according to NASA, while microwave energy (including the kind you use to heat up pizza) is between 1 millimeter and 1 micrometer.

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Paper referenced in the video:
Inter-and intraindividual variability in daily resting heart rate and its associations with age, sex, sleep, BMI, and time of year: Retrospective, longitudinal cohort study of 92,457 adults.
https://pubmed.ncbi.nlm.nih.gov/32023264/

Elon Muskโ€™s Neuralink technology will see its first human implant this year. If youโ€™re excited to see how Muskโ€™s brain chip will work on humans, we might find out very soon.

The brain-interface tech company was founded by Elon Musk in 2016 and its chip will finally be implanted into a human brain this year. In 2021, the implant was seen in action in a monkey who played MindPong. The monkey was able to play the game by simply thinking it, with help from Neuralink chip.

Elon Musk, Neuralink Demonstration, Brain Chip, Fitbit In Skull, Elon Musk News, Technology News, AI Symbiosis Artificial Intelligence, Brain-Machine Interface Elon Musk, Neuralink Demonstration.

During long portions of the past 2.4 billion years, the Earth may have been more inhospitable to life than scientists previously thought, according to new computer simulations.

Using a state-of-the-art climate model, researchers now believe the level of ultraviolet (UV) radiation reaching the Earthโ€™s surface could have been underestimated, with UV levels being up to ten times higher.

UV radiation is emitted by the sun and can damage and destroy biologically important molecules such as proteins.

Sinclairโ€™s first episode. Enjoy.


In this episode, Dr. David Sinclair and co-host Matthew LaPlante discuss why we age. In doing so, they discuss organisms that have extreme longevity, the genes that control aging (mTOR, AMPK, Sirtuins), the role of sirtuin proteins as epigenetic regulators of aging, the process of โ€œex-differentiationโ€ in which cells begin to lose their identity, and how all of this makes up the โ€œInformation Theory of Agingโ€, and the difference between โ€œbiological ageโ€ and โ€œchronological ageโ€ and how we can measure biological age through DNA methylation clocks.

Thank you to our sponsors:
Athletic Greens โ€” https://athleticgreens.com/sinclair.
InsideTracker โ€” https://insidetracker.com/sinclair.
Levels โ€” https://levels.link/sinclair.

Our Patreon page:
https://www.patreon.com/davidsinclair.

Lifespan book:
https://amzn.to/3sUqurT

Dr. David Sinclair Social:
Instagram โ€” https://www.instagram.com/davidsinclairphd.
Twitter โ€” https://twitter.com/davidasinclair.
Facebook โ€” https://www.facebook.com/davidsinclairphd.

Matthew LaPlanteโ€™s Social:
Twitter โ€” https://twitter.com/mdlaplante.

Timestamps:
00:00:00 Introduction.
00:03:14 Goal of the Lifespan Podcast.
00:07:11 Acknowledgement of Sponsors.
00:10:45 Aging is a Controllable Process that can be Slowed & Reversed.
00:16:42 Organisms with Extreme Longevity.
00:21:47 Genes that Regulate Aging: mTOR, AMPK, Sirtuins.
00:21:55 mTOR & Rapamycin.
00:24:33 AMP-activated protein kinase (AMPK) & Metformin.
00:30:57 Sirtuin Proteins as Epigenetic Regulators of Aging.
00:35:33 Ex-Differentiation.
00:43:30 Measuring Aging โ€” Biological Age vs. Chronological Age.
00:49:30 โ€œNo Law That Says We Have To Ageโ€œ
00:50:33 Episode Summary & Key Takeaways โ€” Why Do We Age?
00:54:00 Information Theory of Aging.
00:57:59 Aging is a Medical Condition.
01:01:00 Aging Myths โ€” Telomeres & Antioxidants.
01:01:55 Options for Subscription and Support.

Solar roofing provider GAF Energy announced today its Timberline Solar product uses solar shingles that you can nail to a roof.

GAF Energy, a division of Standard Industries, has made a solar roof system that integrated easily into traditional roofing processes in materials thanks to what it calls the first โ€œnailableโ€ solar shingle, the Timberline Solar Energy Shingle, which will be assembled domestically at GAF Energyโ€™s manufacturing and R&D facility in San Jose, California. The company showed off the tech at the CES 2022 trade event in Las Vegas.

The project will create local American jobs and hopefully create more demand for residential clean energy. One of the challenges to date has been the need to house solar tiles on platforms that have to be attached to roofs, making a solar roof installation more complicated than putting on a traditional roof.