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People in Ethiopia did not live in low valleys during the last ice age. Instead they lived high up in the inhospitable Bale Mountains. There they had enough water, built tools out of obsidian and relied mainly on giant rodents for nourishment. This discovery was made by an international team of researchers led by Martin Luther University Halle-Wittenberg (MLU) in cooperation with the Universities of Cologne, Bern, Marburg, Addis Ababa and Rostock. In the current issue of “Science”, the researchers provide the first evidence that our African ancestors had already settled in the mountains during the Palaeolithic period, about 45,000 years ago.

At around 4,000 metres above sea level, the Bale Mountains in southern Ethiopia are a rather inhospitable region. There is a low level of oxygen in the air, temperatures fluctuate sharply, and it rains a lot. “Because of these adverse living conditions, it was previously assumed that humans settled in the Afro-Alpine region only very lately and for short periods of time,” says Professor Bruno Glaser, an expert in soil biogeochemistry at MLU. Together with an international team of archaeologists, soil scientists, palaeoecologists, and biologists, he has been able to show that this assumption is incorrect. People had already begun living for long periods of time on the ice-free plateaus of the Bale Mountains about 45,000 years ago during the Middle Pleistocene Epoch. By then the lower valleys were already too dry for survival.

For several years, the research team investigated a rocky outcrop near the settlement of Fincha Habera in the Bale Mountains in southern Ethiopia. During their field campaigns, the scientists found a number of stone artefacts, clay fragments and a glass bead. “We also extracted information from the soil as part of our subproject,” says Glaser. Based on the sediment deposits in the soil, the researchers from Halle were able to carry out extensive biomarker and nutrient analyses as well as radiocarbon dating and thus draw conclusions as to how many people lived in the region and when they lived there. For this work, the scientists also developed a new type of palaeothermometer which could be used to roughly track the weather in the region — including temperature, humidity and precipitation. Such analyses can only be done in natural areas with little contamination, otherwise the soil profile will have changed too much by more recent influences.

(CNN)You’ve heard of men on the moon — but what about moss piglets?

Thousands of tardigrades – also known as “water bears” or “moss piglets” — were on board the Beresheet spacecraft when it crash landed on the moon in April.
The tiny creatures are incredibly hardy and can survive extremely low temperatures and harsh conditions– and The Arch Mission Foundation, which sent them into space, believes some may have survived.
Tardigrades are pudgy little animals no longer than one millimeter. They live in water or in the film of water on plants like lichen or moss, and can be found all over the world in some of the most extreme environments, from icy mountains and polar regions to the balmy equator and the depths of the sea.
Tardigrades live all over the world in some of the most extreme environments.

In an attempt to create a “Noah’s ark” or a “back-up” for the Earth, non-profit organization The Arch Mission sent a lunar library — a stack of DVD-sized disks that acts as an archive of 30 million pages of information about the planet — to the moon. Along with the library, Arch Mission sent human DNA samples and a payload of tardigrades, which had been dehydrated, into space.
“We chose them because they are special. They are the toughest form of life we know of. They can survive practically any planetary cataclysm. They can survive in the vacuum of space, they can survive radiation,” Nova Spivack, co-founder of the Arch Mission Foundation, told CNN.
Tardigrades have eight legs with claws at the end, a brain and central nervous system, and a sucker-like pharynx behind their mouth, which can pierce food.
The Arch Mission put the creatures into a state of “suspended animation,” where the body dries out and the metabolism slows to as little as 0.01% of its normal rate.
The Arch Mission also sent a 30 million-page library along for the ride.

“In that state you can later rehydrate them in a laboratory and they will wake up and be alive again,” Spivack explained.
Although the animals won’t be able to reproduce or move around in their dehydrated state — if they have survived the crash — if rehydrated they could come back to life years later.
“We don’t often get a chance to land life on the moon that we decided to seize the day and send some along for the ride,” Spivack added.
Researchers hope that along with the tardigrades, the majority of the information from the lunar library survived the impact of the crash — and could be used to regenerate human life in millions of years.
“Best-case scenario is that the little library is fully intact, sitting on a nice sandy hillside on the moon for a billion years. In the distant future it might be recovered by our descendants or by a future form of intelligent life that might evolve long after we’re gone,” Spivack said.
“From the DNA and the cells that we included, you could clone us and regenerate the human race and other plants and animals,” he added.

Source: https://www.cnn.com/2019/08/07/world/water-bear-space-intl-scli-scn/index.html

For DeepMind, the emergence of the new headquarters is symbolic of a new chapter for the company as it turns its research heft and compute power to try to understand, among other things, the building blocks of organic life. In so doing, the company hopes to make breakthroughs in medicine and other disciplines that will significantly impact progress in a number of fields. “Our mission should be one of the most fascinating journeys in science,” Hassabis says. “We’re trying to build a cathedral to scientific endeavour.”


DeepMind’s AI has beaten chess grandmasters and Go champions. But founder and CEO Demis Hassabis now has his sights set on bigger, real-world problems that could change lives. First up: protein folding.

A paper posted online this month has settled a nearly 30-year-old conjecture about the structure of the fundamental building blocks of computer circuits. This “sensitivity” conjecture has stumped many of the most prominent computer scientists over the years, yet the new proof is so simple that one researcher summed it up in a single tweet.

“This conjecture has stood as one of the most frustrating and embarrassing open problems in all of combinatorics and theoretical computer science,” wrote Scott Aaronson of the University of Texas, Austin, in a blog post. “The list of people who tried to solve it and failed is like a who’s who of discrete math and theoretical computer science,” he added in an email.

The conjecture concerns Boolean functions, rules for transforming a string of input bits (0s and 1s) into a single output bit. One such rule is to output a 1 provided any of the input bits is 1, and a 0 otherwise; another rule is to output a 0 if the string has an even number of 1s, and a 1 otherwise. Every computer circuit is some combination of Boolean functions, making them “the bricks and mortar of whatever you’re doing in computer science,” said Rocco Servedio of Columbia University.

New video from our 2019 Undoing Aging conference: Mikhail Shchepinov, Chief Science Officer at Retrotope, Inc., on aging and diseases resulting from the gradual accumulation of oxidative damages.

undoing-aging.org/videos/mikhail-shchepinov-presenting-at-undoing-aging-2019

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https://www.youtube.com/watch?v=IWWeyOSXA_I&t=1s