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Interesting and I remember coming across similar research a few years ago.


Brain stimulation might sound like some Frankensteinian demonstration from a Victorian science fair. But in reality, it is a contemporary technique making a huge impact in neuroscience by addressing a longstanding limitation of traditional methods for investigating human brain function. Such techniques, like EEG and fMRI, can only be used to infer the effects of a stimulus or task on brain activity, and not vice versa. For example, a scientist might use EEG to study the effect of a task like arm movement on brain activity, but how can one study the effect of brain activity on arm movement?

Today, noninvasive brain stimulation techniques such as transcranial magnetic stimulation (TMS) are offering alternatives to old paradigms. TMS can excite or suppress underlying brain tissue safely and ethically, allowing researchers to study causal relationships between brain circuits and behavior. What’s more, TMS may have therapeutic value in treating brain disorders such as depression.

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Luv this.


Proteins are the workhorse molecules of life. Among their many jobs, they carry oxygen, build tissue, copy DNA for the next generation, and coordinate events within and between cells. Now scientists at the University of North Carolina at Chapel Hill have developed a method to control proteins inside live cells with the flick of a switch, giving researchers an unprecedented tool for pinpointing the causes of disease using the simplest of tools: light.

The work, led by Klaus Hahn and Nikolay Dokholyan and spearheaded by Onur Dagliyan, a graduate student in their labs, builds on the breakthrough technology known as optogenetics. The technique, developed in the early 2000s, allowed scientists, for the first time, to use light to activate and deactivate proteins that could turn brain cells on and off, refining ideas of what individual brain circuits do and how they relate to different aspects of behavior and personality.

Multiplexed optogenetic control, using Photo-inhibitable Vav2 (PA-Vav2) and Photo-inhibitable Rac1 (PI-Rac1) in the same cell.

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There’s an old saying in neuroscience: “neurons that fire together wire together.” This means the more you run a neuro-circuit in your brain, the stronger that circuit becomes. This is why, to quote another old saw, “practice makes perfect”. The more you practice piano, or speaking a language, or juggling, the stronger those circuits get.

Scientists have known this for years. However, nowadays researchers learn another part of the truth: In order to learn something, even more important than practicing is the ability to unlearn, or to break down the old neural connections. This is called “synaptic pruning”.

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Wonder how much this would be really true.


What would happen if everyone in the world had an IQ score over 200 points? This is a type of intelligence that only comes along every so often. An IQ level of 200 is as high, or higher, than the theoretical IQs of history’s greatest minds like Albert Einstein, Leonardo da Vinci, and Isaac Newton.

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In recent research published in the journal Molecular Psychiatry, Northwestern Medicine scientists identified a new pathway in the brain that can be manipulated to alleviate depression.

The pathway offers a promising new target for developing a drug that could be effective in individuals for whom other antidepressants have failed.

New antidepressant options are important because a significant number of patients don’t adequately improve with currently available antidepressant drugs.

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New version of this out: https://www.geneticliteracyproject.org/2017/01/02/americas-refusal-embrace-gene-editing-start-next-cold-war/ #transhumanism #biohacking


Unlike other epic scientific advances…the immediate effect of genetic editing technology is not dangerous. Yet, it stands to be just as divisive to humans as the 70-year proliferation of nuclear weaponry.

The playing field of geopolitics is pretty simple: If China or another country vows to increase its children’s intelligence via genetic editing, and America chooses to remain “au naturel” because they insist that’s how God made them, a conflict species-deep will quickly arise.

This type of idea takes racism and immigration to a whole new level. Will America close off its borders, its jobs, its schools, and its general openness to the world to stay pure, old-fashioned human?

In short, will genetic editing start a new cold war? One that bears much finger pointing and verbal reprimands, including the use of derogatory terms like mutants, cyborgs, and transhumanists.

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In a breakthrough for regenerative medicine, scientists have grown intestinal tissues with functional nerves in a laboratory setup using human pluripotent stem cells. The synthesized tissue was used to study Hirschsprung’s disease, a congenital condition where nerve cells are missing from the colon, causing complications in passing stool. The research is detailed in Nature Medicine.

A pluripotent stem cell is a precursor cell to all the other types of cells in the body. In a petri dish, the stem cells were treated in a biochemical bath that triggered the formation into intestinal tissue. The novel part of the study was the construction of a nervous system on the intestinal organoid. The researchers manipulated neural crest cells to grow a system of nerves. By putting together the neural crest cells and the intestinal tissue at the exact time, they successfully grew together into a complex functional system.

The tissues were transplanted into mice. They worked successfully and showed a structure “remarkably similar” to that of a natural human intestine.

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WHY THIS MATTERS IN BRIEF Every business is becoming a technology business and nowhere is that truer than in the financial services industry, now as banks try to compete with start ups and established technology companies for tech talent they could find themselves getting into warm water…

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