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Imagine a simple and effective treatment for restoring the sense of smell in people who have lost it or never had it in the first place – that could one day be possible as a result of early stage research on mice, in which olfactory nerves were replenished using stem cells.

Using droplets of globose basal cells – the same cells that naturally replace damaged and ageing neurons related to smell – scientists were able to get them to develop into full nerve cells, stretching right into the brain.

Ultimately a few squirts of stem cells were able to reconnect the axons leading to the olfactory signalling in the brains of the mice. Scientists are still a long way from repeating the trick with human beings, but it’s a very promising start.

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https://www.youtube.com/watch?v=IADdW-Af7nA

This week on The #GSPodcast Stephen Knight talks to microbiologist João Pedro de Magalhães (@jpsenescence) about Cryonics. They discuss the fear of dying, the science behind freezing humans, the implications for religion, technological advancements in the field and much, much more!

Support the podcast at http://www.patreon.com/gspellchecker

Also available on iTunes, Stitcher, YouTube & Spotify.

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A tardigrade that had been frozen solid for more than 30 years has been brought back to life by researchers in Japan, and has gone on to produce 14 healthy babies. That’s record-smashing stuff right there, because before this tough little water bear came back to life, the world record for reviving a frozen tardigrade was nine years.

The researchers also thawed out an egg that was collected and frozen with the tardigrade in 1983, and not only did a healthy baby hatch from it six days later, but it went on to successfully produce offspring of its own.

Just a few months after scientists debated the unprecedented amount of foreign DNA that is or isn’t looped up into the tardigrade genome, and the discovery that they turn into ‘bioglass’ when they desiccate, a team from the National Institute of Polar Research in Japan has managed to bring a frozen Antarctic tardigrade (Acutuncus antarcticus) back to life with its reproductive organs fully intact.

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A terminally ill patient who opted for assisted death has undergone cryonic preservation at the Alcor Life Extension Foundation. This preservation—the first of its kind—signifies an important milestone for cryonics advocates, who argue that the right to death, paradoxically, is a potential pathway to an eternal life.

On October 30, 2018, Alcor performed its 164th cryopreservation. It was an otherwise unremarkable moment for the nonprofit organization, save for the way Norman Hardy of Mountain View, California met his demise. Hardy was diagnosed with terminal metastatic prostate cancer, and it had spread to his bones and lungs. As noted in Alcor’s case summary, his “pain had been poorly managed,” so he opted for assisted death, which was legalized in California in 2016 through the End of Life Options Act (EOLOA).

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Aging Analytics Agency has launched an interactive IT-platform alongside its “Longevity Industry in California Landscape Overview 2019” report that turns the report’s static mindmaps into dynamic and interactive infographics, enabling complex interactions between industry entities and stakeholders to be visualized, filtered, searched and thus more easily understood.

Link to IT-Platform: https://mindmaps.aginganalytics.com/longevity-industry-in-california.

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Photo by Erin Ashford Yale University Principal Investigator: David Spiegel Research Team: Prof. Jason Crawford, Nam Kim, Venkata Sabbasani, Matthew Streeter The long-lived collagen proteins that give structure to our arteries and other tissues are continuously exposed to blood sugar and other highly reactive molecules necessary for life. Occasionally, …Glucosepane Crosslinks and Undoing Age-Related Tissue Damage.

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May has been a great month for LEAF; there’s been a lot of exciting news, such as our president’s participation in the XPRIZE Foundation’s most recent meeting, Steve Hill making it among the top 100 journalists covering aging research, and last but not least, the launch of Lifespan.io’s brand-new, life extension-focused show, LifeXtenShow!

LEAF News

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I was live on Good Morning Britain this morning talking transhumanism and life extension. It’s one of the UK’s most popular news shows. The Mirror did a write-up of the story and there’s a 2-min video embed of the interview in the article to watch:


American journalist Zoltan Istvan said that humans will be able to download many versions of themselves onto the internet.

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