Lifeboat Foundation: Safeguarding Humanity
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Category: life extension

The second thing to mention is that in many instances, we actually have cracked it, at least medically. There are endless cutting-edge treatments being deployed as we speak, and endless additional cutting-edge research projects being conducted. There are new breakthroughs all the time, much of which are awaiting FDA approval, but one thing many of these treatments and cures have in common is that they are developed in a tiny country smaller than New Jersey that happens to be located in perhaps the worst neighborhood on Earth. When it comes to cancer research, Israel leads the way.

Finally, the last time I wrote about cutting-edge cancer treatments, I was contacted by a close friend who is a leading oncologist. He pointed out that a disclaimer is very much necessary when I write these articles. The last thing oncologists need is for their patients to think there is some magical solution here and show up to their appointments with a cut-out of an article. In fact, the last thing a cancer patient needs is false hope.

So the disclaimer is that this company is in the clinical trial phase, and if all goes according to plan, tumors might be much more manageable and treatable than they are today, but a lot has to happen before we get there.

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We thank Drs. Michel Bernier and Anne E. Burke for valuable input, Mr. Marc Raley for work on previous versions of the figures, Dr. David G. Le Couteur for assistance with the preparation of an earlier version of the manuscript, and the Intramural Research Program of the National Institute on Aging, National Institutes of Health, for its support.

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Writing in Nature Medicine, an international team headed by researchers at University of California San Diego School of Medicine describe a new way to effectively deliver a gene-silencing vector to adult amyotrophic lateral sclerosis (ALS) mice, resulting in long-term suppression of the degenerative motor neuron disorder if treatment vector is delivered prior to disease onset, and blockage of disease progression in adult animals if treatment is initiated when symptoms have already appeared.

The findings are published in the December 23, 2019 online issue of the journal Nature Medicine. Martin Marsala, MD, professor in the Department of Anesthesiology at UC San Diego School of Medicine and a member of the Sanford Consortium for Regenerative Medicine, is senior author of the study.

ALS is a neurodegenerative that affects nerve cells in the brain and . Motor neurons responsible for communicating movement are specifically harmed, with subsequent, progressive loss of muscle control affecting the ability to speak, eat, move and breathe. More than 5,000 Americans are diagnosed with ALS each year, with an estimated 30,000 persons currently living with the disease. While there are symptomatic treatments for ALS, there is currently no cure. The majority of patients succumb to the disease two to five years after diagnosis.

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Raising hope of effective treatment for age-related macular degeneration (AMD), researchers have found that the brain knows how to integrate natural and artificial vision, while maintaining information processing that is important for vision.

AMD is a common cause of severe vision loss in among those aged 50 and over.

Though there is no cure for AMD, significant recent advancements in artificial retina implants may lead to effective treatment.

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Healthy Japanese foods make it easy to create a vibrant plate that resembles a nutritional masterpiece. The residents of Okinawa, a Japanese prefecture comprising more than 150 islands in the East China Sea, enjoy the longest life expectancy in the world, according to Blue Zones. On the islands, with a population said to include the largest proportion of people over 100, women and men can expect to live 84 and 90 years, respectively.

It’s no secret that diet plays a major role in longevity. The healthy Japanese foods centenarians in Okinawa reach for each day include a variety of riches from the ocean and the earth.

In Okinawa, bitter melons are called “goya” and they’re often found in vegetable dishes. “Bitter melons have an ‘anti-diabetic’ property where they actually assist in lowering blood glucose levels,” says registered dietitian Melissa Rifkin, RD.

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How can you lose dramatic weight, ease chronic conditions, and stay healthier longer? Flip the switch on your metabolism with intermittent fasting, protein cycling, and keto!

Within each of us is an ancient mechanism that eliminates toxic materials, initiates fat burning, and protects cells from becoming dysfunctional—or turning cancerous. It’s called autophagy, and when it’s turned on, the complex operation not only can slow down the aging process, it can optimize biological function as a whole, helping to stave off all manner of diseases and affording us the healthy life spans we never thought possible. It’s the body’s ultimate switch to life.

So how can we positively activate this switch? How frequently should we fast and for how long? Which foods dial up autophagy or, conversely, turn it down? How much exercise and what types are recommended? What’s the sweet spot between intermittent fasting, protein cycling, and ketogenic eating?

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The authors show that early removal of senescent cells in the retina protects the healthy retinal ganglion cells from death to maintain vision. These data suggest the potential application of senolyt…

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In the life extension movement, longevity escape velocity (sometimes referred to as Actuarial escape velocity[1]) is a hypothetical situation in which life expectancy is extended longer than the time that is passing. For example, in a given year in which longevity escape velocity would be maintained, technological advances would increase life expectancy more than the year that just went by.

Life expectancy increases slightly every year as treatment strategies and technologies improve. At present, more than one year of research is required for each additional year of expected life. Longevity escape velocity occurs when this ratio reverses, so that life expectancy increases faster than one year per one year of research, as long as that rate of advance is sustainable.[2][3][4]

The concept was first publicly proposed by David Gobel, co-founder of the Methuselah Foundation (MF). The idea has been championed by biogerontologist Aubrey de Grey[5] (the other co-founder of the MF), and futurist Ray Kurzweil,[6] who named one of his books, Fantastic Voyage: Live Long Enough to Live Forever, after the concept. These two claim that by putting further pressure on science and medicine to focus research on increasing limits of aging, rather than continuing along at its current pace, more lives will be saved in the future, even if the benefit is not immediately apparent.[2].

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