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Crown Bioscience (CrownBio), JSR Life Sciences and Cambridge Quantum Computing (CQC) today announced a partnership agreement to explore the application of quantum technology to drive the identification of multi-gene biomarker discovery for oncology drug discovery.

Dr. John Torday, Ph.D. is an Investigator at The Lundquist Institute of Biomedical Innovation, a Professor of Pediatrics and Obstetrics/Gynecology, and Faculty, Evolutionary Medicine, at the David Geffen School of Medicine at UCLA, and Director of the Perinatal Research Training Program, the Guenther Laboratory for Cell-Molecular Biology, and Faculty in the Division of Neonatology, at Harbor-UCLA Medical Center.

Dr. Torday studies the cellular-molecular development of the lung and other visceral organs, and using the well-established principles of cell-cell communication as the basis for determining the patterns of physiologic development, his laboratory was the first to determine the complete repertoire of lung alveolar morphogenesis. This highly regulated structure offered the opportunity to trace the evolution of the lung from its unicellular origins forward, developmentally and phylogenetically. The lung is an algorithm for understanding the evolution of other physiologic properties, such as in the kidney, skin, liver, gut, and central nervous system. Such basic knowledge of the how and why of physiologic evolution is useful in the effective diagnosis and treatment of disease.

Dr. Torday received his undergraduate degree in Biology and English from Boston University, and his MSc and PhD in Experimental Medicine from McGill University, Montreal, Canada. He did a post-doctoral Fellowship in Reproductive Endocrinology at the University of Wisconsin-Madison, WI.

Dr. Torday’s research has led to the publication of more than 150 peer-reviewed articles and 350 abstracts. More recently, he has gained an interest in the evolutionary aspects of comparative physiology and development, leading to the publication of 12 peer-reviewed articles on the cellular origins of vertebrate physiology, culminating in the book Evolutionary Biology, Cell-Cell Communication and Complex Disease.

Dr. Torday is also the co-author / co-editor on several volumes including: Evolution, the Logic of Biology, Evidence-Based Evolutionary Medicine, Morphogenesis, Environmental Stress and Reverse Evolution, and most recently, The Singularity of Nature: A Convergence of Biology, Chemistry and Physics.

Some genes don’t stay in the same place in the genome. Sometimes called jumping genes or transposons, this genetic material can hop around and rearrange itself | Genetics And Genomics.


Some genetic sequences don’t stay in the same place in the genome. Sometimes called jumping genes or transposons, this genetic material can hop around and rearrange itself to create new sequences. Some transposons even encode for their own enzymes, and these co-called transposases can edit the genome by cutting sequences from one place and pasting them to another.

Reporting in Science, researchers have now suggested that transposable elements (TEs) can fuse with portions of existing genes that code for protein called exons, and get incorporated into genes in a process called exon shuffling to create novel genes that are functional, and express new proteins.

This is a detailed summary of plasma dilution and at 58:38 the future is explained where they will publish human results from 25 people, then start a company whose first order of business will be phase 3 trials with more people and placebo and hopefully funding. It appears you can pay to have the procedure. The hopeful start is this year in may.


Irina will present her recent findings on plasma dilution, showing that age-reversing effects, such as rejuvenating tissues in mice, can be achieved by.
diluting the blood plasma of old mice: Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin.

Irina’s research focus.
A key direction of my laboratory is to understand age-imposed and pathological changes in molecular compositions of systemic and local environments of adult stem cells and to calibrate these to health — youth. In the past few years this direction has been ramified into synthetic biology, CRISPR technologies, bio-orthogonal proteomics and development of innovative digital bio-sensors that we collaboratively applied to the fields of aging and diagnostics of genetic diseases. Success in this research will improve our understanding of the determinants of homeostatic health and will enable novel rational approaches to treat a number of degenerative, fibrotic, metabolic and inflammatory diseases, as a class.

Zoom Transcription:
https://otter.ai/u/yhmNLEM7V52oOfW93lUfDWqL_uw

A trio of researchers with ICAEV, Universidad Austral de Chile, and the University of Liverpool, respectively, have found suppressor genes linked to longevity and less cancer in two species of whales. In their paper published in the journal Proceedings of the Royal Society B, Daniela Tejada-Martinez, João Pedro de Magalhães and Juan C. Opazo, describe their genetic study of longevity in cetaceans and what they learned.

Code of the Wild (Documentary) at Hello Tomorrow in Paris.

www.codeofthewild.org to watch the trailer and explore the film.

George Church, Antonio Regalado, and Josiah Zayner discuss designer babies, moratorium on human germ line engineering, and the future of the genomic revolution with Jane Metcalfe, co-founder of Wired Magizine and founder of Neolife (https://neo.life/)

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DNA variants passed on to modern humans from Neanderthals can increase as well as decrease our ability to fight SARS-CoV-2, a new PNAS study finds. New research has found that a group of genes that reduces the risk of developing severe COVID-19 by around 20% is inherited from Neanderthals Th.

HOW CUTE 🥰 Meet Elizabeth Ann, the first-ever cloned U.S. endangered species. She’s a black-footed ferret duplicated from the genes of an animal that died in 1988.


“You might have been handling a black-footed ferret kit and then they try to take your finger off the next day,” U.S. Fish and Wildlife Service black-footed ferret recovery coordinator Pete Gober said Thursday. “She’s holding her own.”

Elizabeth Ann was born and is being raised at a Fish and Wildlife Service black-footed ferret breeding facility in Fort Collins, Colorado. She’s a genetic copy of a ferret named Willa who died in 1988 and whose remains were frozen in the early days of DNA technology.

Cloning eventually could bring back extinct species such as the passenger pigeon. For now, the technique holds promise for helping endangered species including a Mongolian wild horse that was cloned and last summer born at a Texas facility.