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The discovery of a fossilized, 42-million-year-old, four-legged whale is shedding new light on the evolution and geographical spread of these aquatic mammals.

The ancestors of modern whales and dolphins evolved from a small, four-limbed hoofed animal that lived in south Asia around 50 million years ago, during the Eocene. Fossil evidence suggests these aquatic mammalian pioneers reached North America by 41.2 million years ago, swimming from West Africa across the Atlantic. The surprise discovery of a previously unknown, 42.6-million-year-old quadrupedal whale along the coast of Peru has resulted in an important addendum to this story: Ancient whales made South America, and not North America, their first home in the New World. Details of this discovery were published today in Current Biology.

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Today our middle-aged Universe looks eerily smooth. Too smooth, in fact.

While a rapid growth spurt in space-time would explain what we see, science needs more than nice ideas. It needs evidence that whittles away contending arguments. We might finally know where to look for some.

A team of physicists from the Centre for Astrophysics | Harvard & Smithsonian (CfA) and Harvard University went back to the drawing board on the early Universe’s evolution to give us a way to help those inflation models stand out from the crowd.

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DAILY DOSE | A new cutting-edge cancer treatment has been developed in one of the innovation capitals of the world — Israel. How does it work and why is some of the medical community eagerly awaiting to use it? Accelerated Evolution Biotechnologies CEO Ilan Morad discusses with host Ayman Sikseck.

Story:

Has a cure for cancer finally been found? Maybe, and it may have born right here in Israel.

An Israeli team of scientists is developing an anti-cancer drug that will target several mutations in cancer cells using a combination of several-cancer directed peptides.

The treatment is called MuTaTo, or multi-objective toxin, and is essentially on the scale of a cancer antibiotic.

For more, see our ⬇.

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Bacteria are fast evolving resistance to antibiotics, which is fast-tracking us to a future where our best drugs no longer work and simple infections become life-threatening once again. While new antibiotics are in the works, the bugs will eventually develop resistances to those too, so a longer term strategy might be to prevent them from evolving in the first place. A new study has found that bacteria use clever gambles to adapt – and showed how we could rig the game in our favor.

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Instead, new research by McMaster behavioural scientists shows that in certain cases evolution works in the opposite direction, reversing individual improvements to benefit related members of the same group.

The research appears in the Journal of Evolutionary Biology, where lead author David Fisher shows that the increased evolution of selfless traits — such as sharing food and keeping watch for one another — is mathematically equivalent to the decreased evolution of individually beneficial traits.

“They’re two sides of the same coin,” Fisher explains. “On one side, traits evolve that benefit your kin, but don’t benefit you, because you’re helping your siblings or cousins. On the other side, traits that benefit you but cost your neighbours don’t evolve, because you’re causing damage to related individuals.”

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An international group of researchers including biologists from the University of Maryland found that at least four species of marine ribbon worms independently evolved the ability to regrow a head after amputation.

Regeneration of amputated is uncommon but does exist throughout the —from salamanders, spiders and sea stars that can regrow appendages to a of ribbon worm that can regenerate an entire individual from just a small sliver of tissue. But regenerative abilities were broadly assumed to be an ancient trait that some species managed to hold on to while most others lost through evolution.

This new study, which was published in the March 6, 2019 issue of Proceedings of the Royal Society B, turns that assumption on its head. In a survey of 35 species of marine ribbon , the researchers found that the ability to regenerate an entire head, including a brain, evolved relatively recently in four .

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In the past few decades, a lethal disease has decimated populations of frogs and other amphibians worldwide, even driving some species to extinction. Yet other amphibians resisted the epidemic. Based on previous research, scientists at the INDICASAT AIP, Smithsonian and collaborating institutions knew that skin bacteria could be protecting the animals by producing fungi-fighting compounds. However, this time they decided to explore these as potential novel antifungal sources for the benefit of humans and amphibians.

“Amphibians inhabit humid places favoring the growth of , coexisting with these and other microorganisms in their environment, some of which can be pathogenic,” said Smithsonian scientist Roberto Ibáñez, one of the authors of the study published in Scientific Reports. “As a result of evolution, amphibians are expected to possess that can inhibit the growth of pathogenic and fungi.”

The team first travelled to the Chiriquí highlands in Panama, where the , responsible for the disease chytridiomycosis, has severely affected populations. They collected samples from seven to find out what kind of skin bacteria they harbored.

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