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Category: evolution

Many of the fundamental features of life don’t necessarily have to be the way they are. Chance plays a major role in evolution, and there are always alternate paths that were never explored, simply because whatever evolved previously happened to be good enough. One instance of this idea is the genetic code, which converts the information carried by our DNA into the specific sequence of amino acids that form proteins. There are scores of potential amino acids, many of which can form spontaneously, but most life uses a genetic code that relies on just 20 of them.

Over the past couple of decades, scientists have shown that it doesn’t have to be that way. If you supply bacteria with the right enzyme and an alternative amino acid, they can use it. But bacteria won’t use the enzyme and amino acid very efficiently, as all the existing genetic code slots are already in use.

In a new work, researchers have managed to edit bacteria’s genetic code to free up a few new slots. They then filled those slots with unnatural amino acids, allowing the bacteria to produce proteins that would never be found in nature. One side effect of the reprogramming? No viruses could replicate in the modified bacteria.

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PROCEEDINGS OF THE ROYAL SOCIETY • JUN 3, 2021
Culture drives human evolution more than genetics

I wonder about the thought that only humans do this, and perhaps that somehow culture is separate in some way from biological evolution enmeshed with the rest of the planet?
by University of Maine

Culture is an under-appreciated factor in human evolution, Waring says. Like genes, culture helps people adjust to their environment and meet the challenges of survival and reproduction. Culture, however, does so more effectively than genes because the transfer of knowledge is faster and more flexible than the inheritance of genes, according to Waring and Wood.

Waring and Wood say culture is also special in one important way: it is strongly group-oriented. Factors like conformity, social identity and shared norms and institutions—factors that have no genetic equivalent—make cultural evolution very group-oriented, according to researchers. Therefore, competition between culturally organized groups propels adaptations such as new cooperative norms and social systems that help groups survive better together.

According to researchers, “culturally organized groups appear to solve adaptive problems more readily than individuals, through the compounding value of social learning and cultural transmission in groups.” Cultural adaptations may also occur faster in larger groups than in small ones.

With groups primarily driving culture and culture now fueling human evolution more than genetics, Waring and Wood found that evolution itself has become more group-oriented.

“In the very long term, we suggest that humans are evolving from individual genetic organisms to cultural groups which function as superorganisms, similar to ant colonies and beehives,” Waring says. “The ‘society as organism’ metaphor is not so metaphorical after all.

ORIGINAL PAPER

Timothy M. Waring et al, Long-term gene–culture coevolution and the human evolutionary transition, Proceedings of the Royal Society B: Biological Sciences (2021). DOI: 10.1098/rspb.2021.0538
https://royalsocietypublishing.org/…/10…/rspb.2021.0538
Thanks to Zoomers of the Sunshine Coast BC & Folkstone Design Inc.
#CulturalEvolution

In a new study, University of Maine researchers found that culture helps humans adapt to their environment and overcome challenges better and faster than genetics.

After conducting an extensive review of the literature and evidence of long-term , scientists Tim Waring and Zach Wood concluded that humans are experiencing a special evolutionary transition in which the importance of culture, such as learned knowledge, practices and skills, is surpassing the value of genes as the primary driver of evolution.

Culture is an under-appreciated factor in human evolution, Waring says. Like genes, culture helps people adjust to their environment and meet the challenges of survival and reproduction. Culture, however, does so more effectively than genes because the transfer of knowledge is faster and more flexible than the inheritance of genes, according to Waring and Wood.

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The team says that the technique could be used to develop new vaccines against antibiotic-resistant bacteria, and potentially even wipe out some dangerous strains in a similar way to how smallpox was eradicated.

Pathogens like bacteria and viruses are extremely good at evolving in response to drugs, which can render vaccines ineffective. But now, researchers at ETH Zurich have found a way to weaponize that ability against them, forcing the bugs down harmless evolutionary dead ends.

Microbes are living examples of evolution in action. Darwin’s classic theory says that when lifeforms are exposed to pressures from their environment, some of them will develop new genetic mutations that help them cope better. Since other individuals will be at a disadvantage, the mutations will eventually become the norm throughout a population.

In the world of bacteria and viruses, drugs and vaccines are the environmental pressures that they must overcome. And they do it with frustrating ease, quickly finding ways around the attacks and then swapping those genes like trading cards. The end result is the constant looming threat of antibiotic-resistant “superbugs” that render our best drugs ineffective.

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Full article available at: https://www.regenerativemedicinedaily.com/parasitic-worms… See More.

Humanity has a long and turbulent history with parasites, even today many parts of the world still struggle with rampant parasitic infections, with pathogens such as the malaria parasite claiming hundreds of thousands of lives every year. By their very nature parasites are harmful to our bodies, or at least that has been the prevailing opinion within the scientific community for as long as we have known of their existence. However, the malicious evolution of parasites might very well have produced a positive side effect which we are only just starting to notice.

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An international study led by UNSW researchers has mapped one of the most intact and complete dog genomes ever generated.

The genome sequence of the Basenji dog could have a big impact on the understanding of dog evolution, domestication and canine genetic diseases.

The Basenji—also known as the barkless dog—is an ancient African dog breed which still lives and hunts with tribesmen in the African Congo.

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What is time? What is humankind’s role in the universe? What is the meaning of life? For much of human history, these questions have been the province of religion and philosophy. What answers can science provide?

In this talk, Sean Carroll will share what physicists know, and don’t yet know, about the nature of time. He’ll argue that while the universe might not have purpose, we can create meaning and purpose through how we approach reality, and how we live our lives.

Sean Carroll is a Research Professor of theoretical physics at the California Institute of Technology, and an External Professor at the Santa Fe Institute. His research has focused on fundamental physics and cosmology, especially issues of dark matter, dark energy, spacetime symmetries, and the origin of the universe.

Recently, Carroll has worked on the foundations of quantum mechanics, the emergence of spacetime, and the evolution of entropy and complexity. Carroll is the author of Something Deeply Hidden, The Big Picture, The Particle at the End of the Universe amongst other books and hosts the Mindscape podcast.

“The Passage of Time and the Meaning of Life” was given on May 4, 02021 as part of Long Now’s Seminar series. The series was started in 02003 to build a compelling body of ideas about long-term thinking from some of the world’s leading thinkers. The Seminars take place in San Francisco and are curated and hosted by Stewart Brand. To follow the talks, you can:

Explore the full series: http://longnow.org/seminars.
More ideas on long-term thinking: http://blog.longnow.org.

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Great new episode with guest Ben K.D. Pearce on how and why our own genetic code was able to form in Earth’s warm little ponds as early as 4.5 billion years ago. Please have a listen.

Guest Ben K.D. Pearce, a Ph.D student in astrophysics and astrobiology at McMaster University in Toronto, and an expert on the origins of life’s building blocks here on Earth. We discuss the idea that all the genetic components from which life emerged were incredibly readily available biogenically very early in Earth’s evolution. As early as 4.5 billion years ago. Pearce is part of a group making great strides in learning how this all may have happened in Earth’s very ancient warm little ponds.

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Researchers created an algorithm to identify similar cell types from species – including fish, mice, flatworms and sponges – that have diverged for hundreds of millions of years, which could help fill in gaps in our understanding of evolution.

Cells are the building blocks of life, present in every living organism. But how similar do you think your cells are to a mouse? A fish? A worm?

Comparing cell types in different species across the tree of life can help biologists understand how cell types arose and how they have adapted to the functional needs of different life forms. This has been of increasing interest to evolutionary biologists in recent years because new technology now allows sequencing and identifying all cells throughout whole organisms. “There’s essentially a wave in the scientific community to classify all types of cells in a wide variety of different organisms,” explained Bo Wang, an assistant professor of bioengineering at Stanford University.

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From a purely scientific frame of reference, many quantum phenomena like non-local correlations between distant entities and wave-particle duality, the wave function collapse and consistent histories, quantum entanglement and teleportation, the uncertainty principle and overall observer-dependence of reality pin down our conscious mind being intrinsic to reality. And this is the one thing the current physicalist paradigm fails to account for. Critical-mass anomalies will ultimately lead to the full paradigm shift in physics. It’s just a matter of time.

With consciousness as primary, everything remains the same and everything changes. Mathematics, physics, chemistry, biology are unchanged. What changes is our interpretation as to what they are describing. They are not describing the unfolding of an objective physical world, but transdimensional evolution of one’s conscious mind. There’s nothing “physical” about our physical reality except that we perceive it that way. By playing the “Game of Life” we evolved to survive not to see quantum mechanical reality. At our classical level of experiential reality we perceive ourselves as physical, at the quantum level we are a probabilistic wave function, which is pure information.

No matter how you slice it, reality is contextual, the notion that immediately dismisses ‘observer-independent’ interpretations of quantum mechanics and endorses the Mental Universe hypothesis. But we have to be careful here not to throw the baby out with the bathwater, so to speak. I’d like to make a very important point at this juncture of our discussion: Mental and physical are two sides of the same coin made of information. Both should be viewed as the same substance.

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A research group working at Uppsala University has succeeded in studying ‘translation factors’ – important components of a cell’s protein synthesis machinery – that are several billion years old. By studying these ancient ‘resurrected’ factors, the researchers were able to establish that they had much broader specificities than their present-day, more specialized counterparts.

In order to survive and grow, all cells contain an in-house protein synthesis factory. This consists of ribosomes and associated translation factors that work together to ensure that the complex protein production process runs smoothly. While almost all components of the modern translational machinery are well known, until now scientists did not know how the process evolved.

The new study, published in the journal Molecular Biology and Evolution, took the research group led by Professor Suparna Sanyal of the Department of Cell and Molecular Biology on an epic journey back into the past. A previously published study used a special algorithm to predict DNA sequences of ancestors of an important translation factor called elongation factor thermo-unstable, or EF-Tu, going back billions of years. The Uppsala research group used these DNA sequences to resurrect the ancient bacterial EF-Tu proteins and then to study their properties.

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