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Category: engineering

Watching millions of neurons in the brain interacting with each other is the ultimate dream of neuroscientists! A new imaging method now makes it possible to observe the activation of large neural circuits, currently up to the size of a small-animal brain, in real time and three dimensions. Researchers at the Helmholtz Zentrum München and the Technical University of Munich have recently reported on their new findings in Nature’s journal ‘Light: Science & Applications’.

Nowadays it is well recognized that most brain functions may not be comprehended through inspection of single neurons. To advance meaningfully, neuroscientists need the ability to monitor the activity of millions of neurons, both individually and collectively. However, such observations were so far not possible due to the limited penetration depth of optical microscopy techniques into a living brain.

A team headed by Prof. Dr. Daniel Razansky, a group leader at the Institute of Biological and Molecular Imaging (IBMI), Helmholtz Zentrum München, and Professor of Molecular Imaging Engineering at the Technical University of Munich, has now found a way to address this challenge. The new method is based on the so-called optoacoustics*, which allows non-invasive interrogation of living tissues at centimeter scale depths.

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There are two kinds of people in Washington, DC, says entrepreneur Dean Kamen. There are the policy experts, whom he calls cynics. And there are the scientists, whom he deems optimists.

Kamen, speaking at the White House Frontiers Conference at the University of Pittsburgh, places himself in the latter camp. Unlike policy wonks and politicians who see diseases like Alzheimer’s or ALS as unstoppable scourges, Kamen points out that previously terrifying diseases were all toppled by medical innovation. The plague, polio, smallpox — all were civilization-threatening epidemics until experimental scientists discovered new ways to combat them.

If that sounds like the kind of disruption that the tech industry has unleashed across the rest of the world, that’s no accident. Kamen, the founder of DEKA, a medical R&D company, says that the same trends that have empowered our computers and phones and communication networks will soon power a revolution in health care. He says that medical innovation follows a predictable cycle. First we feel powerless before a disease. Then we seek ways of treating it. Then we attempt to cure it.

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Leading Australian engineer and physicist, Professor Andrea Morello, was today named inaugural recipient of the Rolf Landauer and Charles H. Bennett Award in Quantum Computing by the prestigious American Physical Society, the world’s leading organisation of physicists.

Morello, a professor in UNSW’s School of Electrical Engineering & Telecommunications and head of the Quantum Spin Control group at the Centre for Quantum Computation and Communication Technology, was awarded the prize “for remarkable achievements in the experimental development of spin qubits in silicon”.

The prize, endowed by the International Business Machines Corp, is named for two of the founding fathers of modern information science, both classical and quantum.

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Whenever we lose someone close to us, there’s an inclination, a need even, to sort through our memories of that person. Memories not just in our minds, but our digital memories too—emails, texts, photos, videos, social media posts.

But eventually, we have to stop looking through those texts and photos, because after a while, it’s like listening to a song on repeat for too long. The memories are static, they will never change, shift, and grow like the real person, and you just have to move on.

When Eugenia Kuyda lost her best friend, Roman Mazurenko, she wanted to memorialize him in a different way. As the cofounder of Luka, an artificial intelligence startup which recommends books and restaurants through a chat interface, Kuyda worked with her engineering team to collect thousands of Mazurenko’s texts and create a chatbot based on his personality.

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Check this out.

Engineers at the University of Massachusetts Amherst are leading a research team that is developing a new type of nanodevice for computer microprocessors that can mimic the functioning of a biological synapse—the place where a signal passes from one nerve cell to another in the body. The work is featured in the advance online publication of Nature Materials.

Such neuromorphic computing in which microprocessors are configured more like human brains is one of the most promising transformative computing technologies currently under study.

J. Joshua Yang and Qiangfei Xia are professors in the electrical and computer engineering department in the UMass Amherst College of Engineering. Yang describes the research as part of collaborative work on a new type of memristive device.

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Boston-based startup completes $23 million Series A financing to leverage novel imaging platform of gene locations towards gaining diagnostic insights and delivering therapeutics for cancer, immuno-oncology, infectious diseases, neurological and neuromuscular diseases, brain function and cognitive disorders

BOSTON—()—ReadCoor, Inc., today announced completion of an oversubscribed $23 million Series A financing round and its concurrent launch from Harvard University’s Wyss Institute for Biologically Inspired Engineering. ReadCoor will commercialize the Wyss Institute’s FISSEQ (fluorescent in situ sequencing) technology.

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MIT researchers have designed nanosensors that can profile tumors and may yield insight into how they will respond to certain therapies. The system is based on levels of enzymes called proteases, which cancer cells use to remodel their surroundings.

Once adapted for humans, this type of sensor could be used to determine how aggressive a tumor is and help doctors choose the best treatment, says Sangeeta Bhatia, the John and Dorothy Wilson Professor of Health Sciences and Technology and Electrical Engineering and Computer Science and a member of MIT’s Koch Institute for Integrative Cancer Research.

“This approach is exciting because people are developing therapies that are protease-activated,” Bhatia says. “Ideally you’d like to be able to stratify patients based on their protease activity and identify which ones would be good candidates for these therapies.”

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Hmmm; like the graphic reminds of one of my posts.

In Brief.

  • Quantum computers would run some 100 million times faster than your PC, but they have proven to be a monumental feat of engineering.
  • In a new experiment, physicists managed to stop light, which helps us overcome challenges and brings us close to optical quantum computing.

A team of researchers at The Australian National University (ANU) may have found another work-around to bring us closer to quantum computing: The physicists have managed to find a new way to stop light.

Light was trapped by shining infrared lasers into ultra-cold atomic vapor. While the atoms absorbed some photons, a large amount were left in a frozen state in the atomic cloud — enhancing photon interaction with atoms or other photons.

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A Northwestern Engineering research team has developed a 3D printable ink that produces a synthetic bone implant that rapidly induces bone regeneration and growth. This hyperelastic “bone” material, whose shape can be easily customized, one day could be especially useful for the treatment of bone defects in children.

Bone implantation surgery is never an easy process, but it is particularly painful and complicated for children. With both adults and children, often times bone is harvested from elsewhere in the body to replace the missing bone, which can lead to other complications and pain. Metallic implants are sometimes used, but this is not a permanent fix for growing children.

“Adults have more options when it comes to implants,” said Ramille N. Shah, who led the research. “Pediatric patients do not. If you give them a permanent implant, you have to do more surgeries in the future as they grow. They might face years of difficulty.”

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In Brief.

Tesla and SolarCity are working on making their cars capable of powering a household, and even the entire grid. Using vehicle-to-grid technology, Tesla may be on to something here, and its more than just saving on your electric bills.

Earlier this year, Elon Musk bought SolarCity for at least $2.6 billion, merging the solar engineering company with Tesla. Since then, both have been busy working on a few things. Perhaps the most interesting of these is the promise to cut down on your household electric bill.

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