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Amazon founder Jeff Bezos is officially stepping down from his role as the company’s CEO on July 5. CBSN tech reporter Dan Patterson joins CBSN to discuss the billionaire’s impact on the U.S. economy, politics and more.

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A first-in-human, Phase 1 trial assessing the safety and immunogenicity of an investigational nanoparticle influenza vaccine designed to provide long-lasting protection against multiple flu virus strains has begun at the National Institutes of Health Clinical Center in Bethesda, Maryland. Healthy participants 18 to 50 years old will receive either a licensed seasonal influenza vaccine or the experimental vaccine, FluMos-v1. Scientists from NIH’s National Institute of Allergy and Infectious Diseases (NIAID) developed FluMos-v1 to stimulate antibodies against multiple influenza virus strains by displaying part of the influenza virus hemagglutinin (HA) protein on self-assembling nanoparticle scaffolds. Alicia T. Widge, M.D., of NIAID’s Vaccine Research Center (VRC), is the principal investigator of the NIAID-sponsored single-site trial.

“The health and economic burdens of influenza are substantial, and the world badly needs improved flu vaccines,” said NIAID Director Anthony S. Fauci, M.D. “I am encouraged by the great promise of the VRC nanoparticle vaccine candidate, which so far has performed very well in pre-clinical testing.”

Standard influenza vaccines must be reformulated and administered annually to match changes in the HA protein in the viral strains predicted to dominate in the upcoming influenza season. If the vaccine is not well matched to dominant circulating virus strains, the antibodies elicited may provide sub-optimal protection. So-called universal influenza vaccines are being developed and tested by many research groups and could one day eliminate the need for annual vaccination by generating long-lasting antibodies to protect against many existing or emergent influenza virus strains, including those not represented in the vaccine.

Microsoft has galvanised policy makers across seven Asia-Pacific markets, including Singapore and Indonesia, in a bid to facilitate the sharing of threat intelligence and resources amongst their respective public sector. The US software vendor says “collective” efforts across the region are critical in combating cybersecurity threats, which are inevitable in an increasingly interconnected world.

It noted that Asia-Pacific saw malware and ransomware attacks at higher frequencies, clocking 1.6 and 1.7 times higher, respectively. than the global average. Citing numbers from its 2019 threat report, Microsoft said developing markets such as Indonesia, India, and Sri Lanka were most vulnerable to such threats that year.

It added that cybercrime not only resulted in financial losses and brought down operations, but also posed risks to national security and eroded trust in digital economies.

Germany will invest more than 8 billion euros ($9.74 billion) to fund large-scale hydrogen projects, the Economy and Transport ministries said on Friday, in a step to scale up hydrogen as an alternative to fossil fuels to meet climate targets.

The 62 German projects, supporting chemical, steel and transport industries, are part of a joint European hydrogen project called Hydrogen-IPCEI, the ministries added.

“The fact is: we must and WANT to urgently promote the switch to climate-friendly mobility,” said Transport Minister Andreas Scheuer in a statement.

The pandemic has upended the way people buy—online retail has soared as high-street shops and malls close. Brands are now racing to exploit one of the most important weapons in the battle for buyers: their customers’ data.

Read our special report on the future of shopping here: https://econ.st/2Q8XQC2

Read more of our business coverage: https://econ.st/2OsXUw2

Listen to “Money Talks” weekly podcast on markets, the economy and business: https://econ.st/3cC4lor.

How online sales are affecting supermarket profits: https://econ.st/3ctYwcE

Are brands turning their backs on Amazon? https://econ.st/3cBLGZQ

Amid the rapid digitalisation of China’s economy, the second-biggest in the world, Midea’s factory represents a snapshot of the future – one in which manufacturing processes and employees need to adapt to increased automation and machine-driven learning.


Machines are increasingly taking over China’s assembly lines as manufacturers upgrade and prepare for fewer, higher-skilled workers.

## MATHEMATICS • MAY 24, 2021

# *Noise is commonly discarded, but identifying patterns in noise can be very useful.*

*Generalize the Hearst exponent by adding more coefficients in order to get a more complete description of the changing data. This makes it possible to find patterns in the data that are usually considered noise and were previously impossible to analyze.*

*The development of this mathematical apparatus can solve the issue of parameterisation and analysis of processes for which there is no exact mathematical description. This opens up enormous prospects in describing, analyzing and forecasting complex systems.*

*by moscow institute of physics and technology*

One of the metrics used in economics and natural sciences in time series analysis is the Hurst exponent. It suggests whether the trend present in the data will persist: for example, whether values will continue to increase, or whether growth will turn to decline. This assumption holds for many natural processes and is explained by the inertia of natural systems. For example, lake level change, which is consistent with predictions derived from analysis of the Hurst exponent value, is determined not only by the current amount of water, but also by evaporation rates, precipitation, snowmelt, etc. All of the above is a time-consuming process.

Thanks to folkstone design inc. & zoomers of the sunshine coast BC

**Relevant Stories**

https://www.youtube.com/channel/UCpEBFr960dwZqR-9HtCWIcQ

## ORIGINAL PAPER

Raoul Nigmatullin et al, **Generalized Hurst Hypothesis: Description of Time-Series in Communication Systems**, Mathematics (2021). DOI: 10.3390/math9040381

https://www.mdpi.com/2227-7390/9/4/381

#ComplexSystems #forecasting #Noise #GeneralizedHurstHypothesis.

A team of scientists from MIPT and Kazan National Research Technical University is developing a mathematical apparatus that could lead to a breakthrough in network security. The results of the work have been published in the journal Mathematics.

Complex systems, such as or living organisms, do not have deterministic physical laws to accurately describe them and predict future behavior. In this case, an important role is played by , which describes the behavior of the system in terms of sets of statistical parameters.

Such complex systems are described by trendless sequences, often defined as long-term time series or “noise”. They are fluctuations produced by a combination of different sources and are among the most difficult data to analyze and extract reliable, stable information.

A new topic a new challenge for future civilizations.

I won’t write an introduction I will ask couple of questions to make you think about it.

In the forth industrial revolution are we going to change the way we reproduce? Could be the first step for post-human era in 2040?

How can we change the way we deal with economics? Because economy depends on population grow. In a way or another world population will stop at 11 billion so it is necessary to change the economy.

How can we colonize and expand while fertility rate is going down could another creatures like machines and biological engineered animals help us to expand and the human specie will limit its population?


Freddie Sayers meets Prof Shanna Swan of Mount Sinai, New York.

Accompanying article here: https://unherd.com/thepost/spermageddon-are-humans-going-extinct/

Listen to the podcast here: https://shows.acast.com/lockdowntv-with-freddie-sayers/spermageddon-are-humans-going-extinct.

Is the human race in danger of extinction? That’s the jaw-dropping claim made in Professor Shanna Swan’s new book ‘Count Down: How Our Modern World Is Threatening Sperm Counts, Altering Male and Female Reproductive Development, and Imperiling the Future of the Human Race’. According to the book, sperm counts have dropped almost 60% since 1973 and suggests that they could reach zero by 2045, which would mean no more reproduction and no more babies.

Our Science Editor Tom Chivers wasn’t overly convinced by the thesis, but we wanted to hear Dr Swan out. She argues that chemicals such as “Pthalates”, to be found in everything from ATM receipts to Tupperware plastic, are altering —and endangering — human sexual development, which is getting worse by the year.

Having devoted over 20 years of her career to the study of sperm, the epidemiologist is about as well-credentialed as they come and she is certainly worth listening to. We thank prof Swan for her time and hope you enjoy the discussion.

#sperm #epidemiology #plastics

Dr. Thomas Lovejoy, is an innovative conservation biologist, who is Founder and President of the non-profit Amazon Biodiversity Center, the renowned Biological Dynamics of Forest Fragments Project, and the person who coined the term “biological diversity”.

Dr. Lovejoy currently serves as Professor in the department of Environmental Science and Policy at George Mason University, and as a senior fellow at the United Nations Foundation based in Washington, DC.

Dr. Lovejoy has also served as the World Bank’s chief biodiversity advisor and the lead specialist for environment for Latin America and the Caribbean, the first Biodiversity Chair of the H. John Heinz III Center for Science, Economics and the Environment, President of the Heinz Center, and chair of the Scientific Technical Advisory Panel (STAP) for the Global Environment Facility (GEF), the multibillion-dollar funding mechanism for developing countries in support of their obligations under international environmental conventions.

Spanning the political spectrum, Dr. Lovejoy has served on science and environmental councils under the Reagan, Bush, and Clinton administrations. At the core of these many influential positions are seminal ideas, which have formed and strengthened the field of conservation biology.

In the 1980s, Dr. Lovejoy brought international attention to the world’s tropical rainforests, and in particular, the Brazilian Amazon, where he has worked since 1965.

With multiple co-edited books (including Biodiversity and Climate Change: Transforming the Biosphere; Drones for Conservation — Field Guide for Photographers, Researchers, Conservationists and Archaeologists; Costa Rican Ecosystems; Climate Change and Biodiversity; On the Edge: The State and Fate of the World’s Tropical Rainforests), Dr. Lovejoy is credited as a founder of the field of climate change biology. He also founded the series Nature, the popular long-term series on public television.