The human cells grew inside all 132 of the embryos after just 24 hours. After ten days, 103 chimeric embryos remained. By day 19, however, only three chimeras were left alive – and they were then terminated.
“This knowledge will allow us to go back now and try to re-engineer these pathways that are successful for allowing appropriate development of human cells in these other animals,” Juan Carlos Izpisua Belmonte, genetics professor at the Salk Institute for Biological Sciences in La Jolla, California and co-author of the study, told NPR.
As India struggles to curb the spread of COVID-19 and step up vaccinations, experts have warned the country to prepare for future waves of the pandemic. It’s hoped that US support for a vaccine waiver will see results.
Many people with diabetes endure multiple, painful finger pricks each day to measure their blood glucose. Now, researchers reporting in ACS Sensors have developed a device that can measure glucose in sweat with the touch of a fingertip, and then a personalized algorithm provides an accurate estimate of blood glucose levels.
According to the American Diabetes Association, more than 34 million children and adults in the U.S. have diabetes. Although self-monitoring of blood glucose is a critical part of diabetes management, the pain and inconvenience caused by finger-stick blood sampling can keep people from testing as often as they should.
The researchers made a touch-based sweat glucose sensor with a polyvinyl alcohol hydrogel on top of an electrochemical sensor, which was screen-printed onto a flexible plastic strip. When a volunteer placed their fingertip on the sensor surface for 1 minute, the hydrogel absorbed tiny amounts of sweat. Inside the sensor, glucose in the sweat underwent an enzymatic reaction that resulted in a small electrical current that was detected by a hand-held device.
Deep-tech healthcare & energy investments for a sustainable future — dr. anil achyuta, investment director / founding member, TDK ventures.
Dr. Anil Achyuta is an Investment Director and a Founding Member at TDK Ventures, which is a deep-tech corporate venture fund of TDK Corporation, the Japanese multinational electronics company that manufactures electronic materials, electronic components, and recording and data-storage media.
Anil is passionate about energy and healthcare sectors as he believes these are the most impactful areas to building a sustainable future – a mission directly in line with TDK Ventures’ goal.
At TDK Ventures, Anil has reviewed over 1050 start-ups and invested in: 1) Autoflight — an electric vertical take-off and landing company, 2) Genetesis — a magnetic imaging-based cardiac diagnostics company, 3) Origin — 3D printing mass manufacturing company, 4) Exo — hand-held 3D ultrasound imaging company, 5) GenCell — ammonia-to-energy hydrogen fuel cell company, 6) Mojo Vision – augmented reality contact lens company, and 7) Battery Resourcers – a direct to cathode lithium ion battery recycling company.
From his seven investments, Anil has secured two exits. GenCell IPO’d on Tel Aviv’s Stock Exchange, and Origin was acquired by the #1 3D Printing company in the world, Stratasys, for $100M.
Anil was voted as one of the Rising Stars in 2021 by Venture Capital Journal and recently, Anil was ranked #2 Rising Star in 2021 out 20000 corporate venturing managers globally.
Prior to TDK Ventures, Anil held leadership roles at Fortune 500 companies including L’Oréal, Johnson & Johnson, GlaxoSmithKline, and Draper.
Anil has a Ph.D. in Chemical Engineering from Northeastern University and has authored over 15 peer-reviewed journal publications and 5 US patents.
Needless to say, DNA is the “instructions” via which our genes are transferred between us and our offspring. And RNA is in charge of regulating the production of proteins in a body, and its so-called “instructions” that it gives are for cellular structure.
To be clear: RNA and DNA serve different functions, and, as the Centers for Disease Control and Prevention (CDC) explains, mRNA vaccines don’t affect or even interact with our DNA at all.
In this week’s Pandemic Problems column, a reader asks how to explain mRNA vaccines to a worried family member.
CHOP team treated patient with the condition, known as PU.MA, thanks to a bone marrow donation from the patient’s older brother.
When Luke Terrio was about seven months old, his mother began to realize something was off. He had constant ear infections, developed red spots on his face, and was tired all the time. His development stagnated, and the antibiotics given to treat his frequent infections stopped working. His primary care doctor at Children’s Hospital of Philadelphia (CHOP) ordered a series of blood tests and quickly realized something was wrong: Luke had no antibodies.
At first, the CHOP specialists treating Luke thought he might have X-linked agammaglobulinemia (XLA), a rare immunodeficiency syndrome seen in children. However, as the CHOP research team continued investigating Luke’s case, they realized Luke’s condition was unlike any disease described before.
What Are ‘COVID Nails’—And Are They a Sign You’ve Had the Virus? Here’s What Doctors Say.
Tim Spector, a British epidemiologist and principal investigator of the Zoe COVID Symptom Study app, recently tweeted about the phenomenon and included a photo of COVID nails, writing, “Do your nails look odd? COVID nails are increasingly being recognized as the nails recover after infection and the growth recovers leaving a clear line. Can occur without skin rashes and appears harmless.”
Some people in the comments said they’ve definitely experienced this after having the coronavirus. “I noticed this and also hair loss 3 months after covid,” one wrote. “These were my post Covid nails! This was approx 2 months after the infection,” another said.
Plenty of others had questions in the comments section about COVID nails, what they look like, and if they’re something to worry about. Here’s what you need to know about COVID nails.
Mastering meat production in this way will lead to advances in medical science and treatment.
“Cultured meat also ultimately offers the opportunity to create meat products that are more well-defined, tunable, and potentially healthier than meat products today, which are constrained by the biological limitations of the domestic animals from which they are derived.”
Owing to advances in industrial-scale cell culture process, the production of cultured meat has been largely standardized. Typically stem cells are first seeded into extracellular matrix scaffolds usually made of edible biomaterials like collagen and chitin. To support cellular metabolic activities, culture media containing nutrients like glucose and sera are next added to the bioreactor where continual mechanical motion facilitates good diffusion of nutrients and oxygen into and removal of metabolic waste products from the cells. After about 2–8 weeks, the cells grow into tissue layers and can be harvested and packaged.
Several key challenges remain in producing cultured meat including access to (proprietary) cell lines, high raw material cost, animal-source nutrients, and limited manufacturing scale. Despite this, immense progress has been made over the last decade. Here, we discuss the challenges and solutions to deliver cultured meat from a lab bench to a dining table.
These findings may have implications for brain disease, disorders.
Scientists at the Krembil Brain Institute, part of University Health Network (UHN), in collaboration with colleagues at the Centre for Addiction and Mental Health (CAMH), have used precious and rare access to live human cortical tissue to identify functionally important features that make human neurons unique.
This experimental work is among the first of its kind on live human neurons and one of the largest studies of the diversity of human cortical pyramidal cells to date.
Summary: A new study sheds light on how highly sensitive people process information. After experiencing something emotionally evocative, brain activity displayed a depth of processing while at rest. Depth of processing is a key feature of high emotional sensitivity.
Source: UC Santa Barbara.
You know that raw overwhelm people have been reporting after months of a pandemic, compounded by economic issues and social unrest? Does fatigue and compulsive social media scrolling strike a familiar chord?
