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The Stoic philosophical school shares several ideas with modern attempts at prolonging human lifespan. The Stoics believed in a non-dualistic, deterministic paradigm, where logic and reason formed part of their everyday life. The aim was to attain virtue, taken to mean human excellence.

I have recently described a model specifically referring to indefinite lifespans, where human biological immortality is a necessary and inevitable consequence of natural evolution (for details see www.elpistheory.info and for a comprehensive summary see http://cid-3d83391d98a0f83a.office.live.com/browse.aspx/Immortality?uc=1&sa=155370157).

This model is based on a deterministic, non-dualistic approach, described by the laws of Chaos theory (dynamical systems) and suggests that, in order to accelerate the natural transition from human evolution by natural selection to a post-Darwinian domain (where indefinite lifespans are the norm) , it is necessary to lead a life of constant intellectual stimulation, innovation and avoidance of routine (see http://www.liebertonline.com/doi/abs/10.1089/rej.2005.8.96?journalCode=rej and http://www.liebertonline.com/doi/abs/10.1089/rej.2009.0996) i.e. to seek human virtue (excellence, brilliance, and wisdom, as opposed to mediocrity and routine). The search for intellectual excellence increases neural inputs which effect epigenetic changes that can up-regulate age repair mechanisms.

Thus it is possible to conciliate the Stoic ideas with the processes that lead to both technological and developmental Singularities, using approaches that are deeply embedded in human nature and transcend time.

Dear Ray;

I’ve written a book about the future of software. While writing it, I came to the conclusion that your dates are way off. I talk mostly about free software and Linux, but it has implications for things like how we can have driverless cars and other amazing things faster. I believe that we could have had all the benefits of the singularity years ago if we had done things like started Wikipedia in 1991 instead of 2001. There is no technology in 2001 that we didn’t have in 1991, it was simply a matter of starting an effort that allowed people to work together.

Proprietary software and a lack of cooperation among our software scientists has been terrible for the computer industry and the world, and its greater use has implications for every aspect of science. Free software is better for the free market than proprietary software, and there are many opportunities for programmers to make money using and writing free software. I often use the analogy that law libraries are filled with millions of freely available documents, and no one claims this has decreased the motivation to become a lawyer. In fact, lawyers would say that it would be impossible to do their job without all of these resources.

My book is a full description of the issues but I’ve also written some posts on this blog, and this is probably the one most relevant for you to read: https://lifeboat.com/blog/2010/06/h-conference-and-faster-singularity

Once you understand this, you can apply your fame towards getting more people to use free software and Python. The reason so many know Linus Torvalds’s name is because he released his code as GPL, which is a license whose viral nature encourages people to work together. Proprietary software makes as much sense as a proprietary Wikipedia.

I would be happy to discuss any of this further.

Regards,

-Keith
—————–
Response from Ray Kurzweil 11/3/2010:

I agree with you that open source software is a vital part of our world allowing everyone to contribute. Ultimately software will provide everything we need when we can turn software entities into physical products with desktop nanofactories (there is already a vibrant 3D printer industry and the scale of key features is shrinking by a factor of a hundred in 3D volume each decade). It will also provide the keys to health and greatly extended longevity as we reprogram the outdated software of life. I believe we will achieve the original goals of communism (“from each according to their ability, to each according to their need”) which forced collectivism failed so miserably to achieve. We will do this through a combination of the open source movement and the law of accelerating returns (which states that the price-performance and capacity of all information technologies grows exponentially over time). But proprietary software has an important role to play as well. Why do you think it persists? If open source forms of information met all of our needs why would people still purchase proprietary forms of information. There is open source music but people still download music from iTunes, and so on. Ultimately the economy will be dominated by forms of information that have value and these two sources of information – open source and proprietary – will coexist.
———
Response back from Keith:
Free versus proprietary isn’t a question about whether only certain things have value. A Linux DVD has 10 billion dollars worth of software. Proprietary software exists for a similar reason that ignorance and starvation exist, a lack of better systems. The best thing my former employer Microsoft has going for it is ignorance about the benefits of free software. Free software gets better only as more people use it. Proprietary software is an inferior development model and an anathema to science because it hinders people’s ability to work together. It has infected many corporations, and I’ve found that PhDs who work for public institutions often write proprietary software.

Here is a paragraph from my writings I will copy here:

I start the AI chapter of my book with the following question: Imagine 1,000 people, broken up into groups of five, working on two hundred separate encyclopedias, versus that same number of people working on one encyclopedia? Which one will be the best? This sounds like a silly analogy when described in the context of an encyclopedia, but it is exactly what is going on in artificial intelligence (AI) research today.

Today, the research community has not adopted free software and shared codebases sufficiently. For example, I believe there are more than enough PhDs today working on computer vision, but there are 200+ different codebases plus countless proprietary ones. Simply put, there is no computer vision codebase with critical mass.

We’ve known approximately what a neural network should look like for many decades. We need “places” for people to work together to hash out the details. A free software repository provides such a place. We need free software, and for people to work in “official” free software repositories.

“Open source forms of information” I have found is a separate topic from the software issue. Software always reads, modifies, and writes data, state which lives beyond the execution of the software, and there can be an interesting discussion about the licenses of the data. But movies and music aren’t science and so it doesn’t matter for most of them. Someone can only sell or give away a song after the software is written and on their computer in the first place. Some of this content can be free and some can be protected, and this is an interesting question, but mostly this is a separate topic. The important thing to share is scientific knowledge and software.

It is true that software always needs data to be useful: configuration parameters, test files, documentation, etc. A computer vision engine will have lots of data, even though most of it is used only for testing purposes and little used at runtime. (Perhaps it has learned the letters of the alphabet, state which it caches between executions.) Software begets data, and data begets software; people write code to analyze the Wikipedia corpus. But you can’t truly have a discussion of sharing information unless you’ve got a shared codebase in the first place.

I agree that proprietary software is and should be allowed in a free market. If someone wants to sell something useful that another person finds value in and wants to pay for, I have no problem with that. But free software is a better development model and we should be encouraging / demanding it. I’ll end with a quote from Linus Torvalds:

Science may take a few hundred years to figure out how the world works, but it does actually get there, exactly because people can build on each others’ knowledge, and it evolves over time. In contrast, witchcraft/alchemy may be about smart people, but the knowledge body never “accumulates” anywhere. It might be passed down to an apprentice, but the hiding of information basically means that it can never really become any better than what a single person/company can understand.
And that’s exactly the same issue with open source (free) vs proprietary products. The proprietary people can design something that is smart, but it eventually becomes too complicated for a single entity (even a large company) to really understand and drive, and the company politics and the goals of that company will always limit it.

The world is screwed because while we have things like Wikipedia and Linux, we don’t have places for computer vision and lots of other scientific knowledge to accumulate. To get driverless cars, we don’t need any more hardware, we don’t need any more programmers, we just need 100 scientists to work together in SciPy and GPL ASAP!

Regards,

-Keith

(End of series. For previous topics please see parts I-IX)

Power plants. Trees could do a lot, as we have seen — and they’re solar powered, too. Once trees can suck metals from the soil and grow useful, shaped objects like copper wire, a few more levels of genetic engineering could enable the tree to use this copper wire to deliver electricity. Since a tree is already, now, a solar energy converter, we can build on that by having the tree grow tissues that convert energy into electricity. Electric eels can already do that, producing enough of a jolt to be lethal to humans. Even ordinary fish produce small amounts of electricity to create electric fields in the water around them. Any object nearby disrupts the field, enabling the fish to tell that something is near, even in total darkness. We may never be able to plug something into a swimming fish but we can already make batteries out of potatoes. So why not trees that grow into electricity providers all by themselves? It would be great to be able to plug your electrical devices into a tree (or at least a socket in your house that is connected to the tree). Then you would no longer need to connect to the grid, purchase solar panels, or install a windmill. You would, however, need to keep your trees healthy and vigorous! Tree care specialists would become a highly employable occupation.

Greening the desert. The Sahara and various other less notorious but still very dry deserts around the world have plenty of sand and rocks. But they don’t have much greenery. The main problem is lack of water. Vast swaths of the Sahara, for example, are plant free. It’s just too dry. However this problem is solvable! Cacti and other desert plants could potentially extract water from the air. Plants already extract carbon dioxide molecules from the air. Even very dry air contains considerable water vapor, so why not extract water molecules too. Indeed, plants already transport water molecules in the ground into their roots, so is it really such a big step to do the same from the air? Tillandsia (air plant) species can already pull in water with their leaves, but it has to be rain or other liquid water. Creating plants that can extract gaseous water vapor from the air in a harsh desert environment would require sophisticated genetic engineering, or a leap for mother nature, but it is still only the first step. Plants get nutrients out of the soil by absorbing fluid that has dissolved them, so dry soil would be a problem even for a plant that contained plenty of water pulled from the air. Another level of genetic engineering or natural evolution would be required to enable them to secrete fluid out of their roots to moisten chunks of soil to dissolve its minerals, and reabsorb the now nutritious, mineral-laden liquid back into their roots.

Once this difficult task is accomplished, whether by natural evolution in the distant future or genetic engineering sooner, things will be different in the desert. Canopies of vegetation that hide the ground will be possible. Thus shaded and sheltered, the ground will be able to support a much richer ecosystem of creatures and maybe even humans than is currently the case in deserts. One of Earth’s harshest environments would be tamed.

Phyto-terraforming. To terraform means to transform a place into an Earth-like state (terra is Latin for Earth). Mars for example is a desert wasteland, but it once ran with rivers, and it would be great if the Martian surface was made habitable — in other words, terraformed. Venus might be made habitable if we could only get rid of its dense blanket of carbon dioxide, which causes such a severe greenhouse effect that its surface is over 800 degrees Fahrenheit, toasty indeed. And why not consider terraforming inhospitable terrain right here on earth, like the Sahara desert, or Antarctica. Phyto-terraforming is terraforming using plants. Actually plants are so favored for this task that when people discuss terraforming, they usually mean phyto-terraforming. Long ago, plants did in fact terraform the Earth, converting a hostile atmosphere with no oxygen but plenty of carbon dioxide into a friendly one with enough oxygen that we can comfortably exist. Plants worked on Earth, and might work on Mars or even Venus, but not on the moon. The reason is that plants need carbon dioxide and water. Venus has these (and reasonable temperatures) high in the atmosphere, suggesting airborne algae cells. Mars is a more likely bet as it has water (as ice) available to surface-dwelling plants at least in places.

If Mars is the most likely candidate for phyto-terraforming, what efforts have been made to move in that direction? A first step has been to splice genes into ordinary plants from an organism that lives in hot water associated with deep ocean thermal vents. This organism is named Pyrococcus furiosus (Pyro- means fire in Greek, coccus refers to ball-shaped bacteria, hence “fireball”). Pyrococcus is most comfortable living at about the boiling point of water and can grow furiously, double its population in 37 minutes. It has evolved genes for destroying free radicals that work better than those naturally present in plants. Free radicals are produced by certain stressors in plants (and humans), cause cell damage, and can even lead to death of the organism. By splicing such genes into the plant Arabidopsis thaliana, the experimental mouse of plant research, this small and nondescript-looking plant can be made much more resistant to heat and lack of water. These genes have also been spliced into tomatoes, which could help feed future colonists. Of course Mars requires cold, not heat tolerance, but the lack of water part is a good start. The heat and drought parts might be useful for building plants to terraform deserts here on Earth, bringing terraforming of Earth deserts a couple of steps closer. With several additional levels of genetic modification, we might eventually terraform Mars yet.

Recommendations

When the advances described here are likely to happen would be good to know. Will they occur in your lifetime? Your grandchildren’s? Thousands or millions of years into the future? If the latter, there is not much point in devoting precious national funds to help bring them about, but if the former, it might be worth the expense of hurrying the process along. To determine the likely timing of future technological advances, we need to determine the speed of advancement. To measure this speed, we can look at the rate at which advances have occurred in the past, and ask what will happen in the future if advances continue along at the same rate. This approach is influential in the modern computer industry in the guise of “Moore’s Law.” However it was propounded at least as early as about 2,500 years ago, when Chinese philosopher Confucius is said to have noted, “Study the past if you would divine the future.” It would be nice to know when we can expect to grow and eat potatoes with small hamburgers in the middle, pluck nuggets of valuable metals from trees, power our homes by plugging into electricity-generating trees growing in our back yards, or terraform Mars.

Opening the floodgates of genetic engineering innovation. Properly regulated to optimally benefit society, genetic engineering of plants has enormous potential, from better and better-tasting food to growing amazing things on trees. However governmental regulation is currently suppressing such advances. Preparing applications to government regulatory agencies for permission to commercially grow genetically engineered plants currently costs many millions of dollars in many countries. Thus only genetic modifications to major commodity crops like corn and soy are generally cost-effective to commercialize. Worse, only big agribusinesses can afford the costs. And why should they object? After all, who needs small, game-changing startup companies moving in, upending the status quo, creating new economic growth and value with new kinds of crops, and generally making life complicated for the giant agribusinesses? Simpler just to keep the costs of applying for permission to grow so high that such upstarts are kept out of the picture. That way predictable profits flow in even if, overall, innovation and the consequent economic expansion is suppressed. But you can’t blame the giants, which are legally obligated to serve the interests of their shareholders. It is illegal for a corporation in the US to further the interests of society at substantial expense to its shareholders! Governments should regulate commercialization of genetically engineered crops optimally, protecting the world from harmful frankenplants while promoting exciting, progressive and beneficial crop innovations.

References

“We may never be able to plug something into a swimming fish, but we can already make batteries out of potatoes.” A. Golberg, H. D. Rabinowitch, and B. Rubinsky, Zn/Cu-vegetative batteries, bioelectrical characterizations, and primary cost analyses, Journal of Renewable Sustainable Energy (2010), Vol. 2, Issue 3, http://jrse.aip.org/jrsebh/v2/i3/p033103_s1, doi:10.1063/1.3427222.

“This organism is named Pyrococcus furiosus…”: G. Fiala and K. O. Stetter, Pyrococcus furiosus sp. nov. represents a novel genus of marine heterotrophic archaebacteria growing optimally at 100°C, Archives of Microbiology (June 1986), vol. 145, no. 1, pp. 56–61.

“By splicing such genes into the plant Arabidopsis thaliana…this small and nondescript-looking plant can be made much more resistant to heat and lack of water.” W. F. Boss and A. M. Grunden, Redesigning living organisms to survive on Mars, NASA Institute for Advance Concepts Annual Meeting (2006), http://www.niac.usra.edu/files/library/meetings/annual/oct06/1194Boss.pdf

“They have also been spliced into tomatoes, which could help feed future colonists.” W. Boss, http://www.cals.ncsu.edu/plantbiology/BossLab/hfiles/overview.html, 5/29/10.

I’m working on this project with Institute for the Future — calling on voices everywhere for ideas to improve the future of global health. It would be great to get some visionary Lifeboat ideas entered!

INSTITUTE FOR THE FUTURE ANNOUNCES BODYSHOCK:
CALL FOR ENTRIES ON IDEAS TO TRANSFORM LIFESTYLES AND THE HUMAN BODY TO IMPROVE HEALTH IN THE NEXT DECADE

“What can YOU envision to improve and reinvent health and well-being for the future?” Anyone can enter, anyone can vote, anyone can change the future of global health.

With obesity, diabetes, and chronic disease rampaging populations around the world, Institute for the Future (IFTF) is turning up the volume on global well-being. Launching today, IFTF’s BodyShock is the first annual competition with an urgent challenge to recruit crowdsourced designs and solutions for better health–to remake the future by rebooting the present.

BodyShock calls upon the public to consider innovative ways to improve individual and collective health over the next 3–10 years by transforming our bodies and lifestyles. Video or graphical entries illustrating new ideas, designs, products, technologies, and concepts, will be accepted from people around the world until September 1, 2010. Up to five winners will be flown to Palo Alto, California on October 8 to present their ideas and be connected to other innovative thinkers to help bring these ideas to life. The grand prize winner will receive the IFTF Roy Amara Prize of $3,000.

“Health doesn’t happen all at once; it’s a consequence of years of choices for our bodies and lifestyles–some large and some small. BodyShock is intended to spark new ideas to help us find our way back to health,” said Thomas Goetz, executive editor of Wired, author of The Decision Tree, and a member of the Health Advisory Board that will be judging the BodyShock contest in addition to votes from the public.

“BodyShock is a fantastic initiative. Global collaboration and participation from all voices can produce a true revolution,” said Linda Avey, founder of Brainstorm Research Foundation and another Advisor to BodyShock.

Entries may come from anyone anywhere and can include, but are not limited to, the following: Life extension, DIY Bio, Diabetic teenagers, Developing countries, Green health, Augmented reality, Self-tracking, and Pervasive games. Participants are challenged to use IFTF’s Health Horizons forecasts for the next decade of health and health care as inspiration, and design a solution for a problem that will be widespread in 3–10 years, using technologies that will become mainstream.

“Think ‘artifacts from the future’–simple, non-obvious, high-impact solutions that don’t exist yet, will be among the concepts we’re looking to the public to introduce,” said Rod Falcon, director of the Health Horizons Program at IFTF.

BodyShock’s grand prize, the Roy Amara Prize, is named for IFTF’s long-time president Roy Amara (1925−2000) and is part of a larger program of social impact projects at IFTF honoring his legacy, known as The Roy Amara Fund for Participatory Foresight, the Fund uses participatory tools to translate foresight research into concrete actions that address future social challenges.

PANEL OF COMPETITION JUDGES

Joanne Andreadis
Lead of Innovation, Centers for Disease Control and Prevention

Linda Avey
Founder, Brainstorm Research Foundation

Jason Bobe
Director of Community, Personal Genome Project
Founder, DIYBio.org

Alexandra Carmichael
Co-founder, CureTogether
Director, Quantified Self

Ted Eytan, MD
Kaiser Permanente, The Permanente Federation

Rod Falcon
Director, Health Horizons Program

Peter Friess
President, Tech Museum of Innovation

Thomas Goetz
Executive Editor, WIRED Magazine
Author, The Decision Tree

Natalie Hodge,MD FAAP
Chief Health Officer, Personal Medicine International

Ellen Marram
Board of Trustees, Institute for the Future
President, Barnegat Group LLC

Kristi Miller Durazo
Senior Strategy Advisor, American Heart Association

David Rosenman
Director, Innovation Curriculum
Center for Innovation at Mayo Clinic

Amy Tenderich
Board Member, Journal of Participatory Medicine
Blogger, DiabetesMine.com

DETAILS

WHAT:
An online competition for visual design ideas to improve global health over the next 3–10 years by transforming our bodies and lifestyles. Anyone can enter, anyone can vote, anyone can change the future of health.

WHEN:
Launch — Friday, June 18,2010

Deadline for entries –Wednesday, September 1, 2010

Winners announced –Thursday, September 23, 2010

BodyShock Winners Celebration at IFTF — 6 — 9 p.m. Friday, October 8, 2010 — FREE and open to the public

WHERE:

http://www.bodyshockthefuture.org

(and 124 University Ave, 2ndFloor, Palo Alto, CA)

Wendy McElroy brings an important issue to our attention — the increasing criminalization of filming / recording on-duty police officers.

The techno-progressive angle on this would have to take sousveillance into consideration. If our only response to a surveillance state is to observe “from the bottom” (as, for example, Steve Mann would have it), and if that response is made illegal, it seems that the next set of possible steps forward could include more entrenched recording of all personal interaction.

Already we have a cyborg model for this — “eyeborgs” Rob Spence and Neil Harbisson. So where next?

Resources:

http://www.nytimes.com/2006/12/10/magazine/10section3b.t-3.html

http://en.wikipedia.org/wiki/Steve_Mann

http://eyeborgproject.com/

http://jointchiefs.blogspot.com/2010/06/camera-as-gun-drop-shooter.html

http://es.wikipedia.org/wiki/Neil_Harbisson

With our growing resources, the Lifeboat Foundation has teamed with the Singularity Hub as Media Sponsors for the 2010 Humanity+ Summit. If you have suggestions on future events that we should sponsor, please contact [email protected].

The summer 2010 “Humanity+ @ Harvard — The Rise Of The Citizen Scientist” conference is being held, after the inaugural conference in Los Angeles in December 2009, on the East Coast, at Harvard University’s prestigious Science Hall on June 12–13. Futurist, inventor, and author of the NYT bestselling book “The Singularity Is Near”, Ray Kurzweil is going to be keynote speaker of the conference.

Also speaking at the H+ Summit @ Harvard is Aubrey de Grey, a biomedical gerontologist based in Cambridge, UK, and is the Chief Science Officer of SENS Foundation, a California-based charity dedicated to combating the aging process. His talk, “Hype and anti-hype in academic biogerontology research: a call to action”, will analyze the interplay of over-pessimistic and over-optimistic positions with regards of research and development of cures, and propose solutions to alleviate the negative effects of both.

The theme is “The Rise Of The Citizen Scientist”, as illustrated in his talk by Alex Lightman, Executive Director of Humanity+:

“Knowledge may be expanding exponentially, but the current rate of civilizational learning and institutional upgrading is still far too slow in the century of peak oil, peak uranium, and ‘peak everything’. Humanity needs to gather vastly more data as part of ever larger and more widespread scientific experiments, and make science and technology flourish in streets, fields, and homes as well as in university and corporate laboratories.”

Humanity+ Summit @ Harvard is an unmissable event for everyone who is interested in the evolution of the rapidly changing human condition, and the impact of accelerating technological change on the daily lives of individuals, and on our society as a whole. Tickets start at only $150, with an additional 50% discount for students registering with the coupon STUDENTDISCOUNT (valid student ID required at the time of admission).

With over 40 speakers, and 50 sessions in two jam packed days, the attendees, and the speakers will have many opportunities to interact, and discuss, complementing the conference with the necessary networking component.

Other speakers already listed on the H+ Summit program page include:

  • David Orban, Chairman of Humanity+: “Intelligence Augmentation, Decision Power, And The Emerging Data Sphere”
  • Heather Knight, CTO of Humanity+: “Why Robots Need to Spend More Time in the Limelight”
  • Andrew Hessel, Co-Chair at Singularity University: “Altered Carbon: The Emerging Biological Diamond Age”
  • M. A. Greenstein, Art Center College of Design: “Sparking our Neural Humanity with Neurotech!”
  • Michael Smolens, CEO of dotSUB: “Removing language as a barrier to cross cultural communication”

New speakers will be announced in rapid succession, rounding out a schedule that is guaranteed to inform, intrigue, stimulate and provoke, in moving ahead our planetary understanding of the evolution of the human condition!

H+ Summit @ Harvard — The Rise Of The Citizen Scientist
June 12–13, Harvard University
Cambridge, MA

You can register at http://www.eventbrite.com/event/648806598/friendsofhplus/4141206940.

Nature News reports of a growing concern over different standards for DNA screening and biosecurity:

“A standards war is brewing in the gene-synthesis industry. At stake is the way that the industry screens orders for hazardous toxins and genes, such as pieces of deadly viruses and bacteria. Two competing groups of companies are now proposing different sets of screening standards, and the results could be crucial for global biosecurity.

“If you have a company that persists with a lower standard, you can drag the industry down to a lower level,” says lawyer Stephen Maurer of the University of California, Berkeley, who is studying how the industry is developing responsible practices. “Now we have a standards war that is a race to the bottom.”

For more than a year a European consortium of companies called the International Association of Synthetic Biology (IASB) based in Heidelberg, Germany, has been drawing up a code of conduct that includes gene-screening standards. Then, at a meeting in San Francisco last month, two of the leading companies — DNA2.0 of Menlo Park, California, and Geneart of Regensburg, Germany — announced that they had formulated a code of conduct that differs in one key respect from the IASB recommendations.”

Read the entire article on Nature News.

Also read “Craig Venter’s Team Reports Key Advance in Synthetic Biology” from JCVI.

Abstract:

President Obama disbanded the President’s Council on Bioethics after it questioned his policy on embryonic stem cell research. White House press officer Reid Cherlin said that this was because the Council favored discussion over developing a shared consensus. This column lists a number of problems with Obama’s decision, and with his position on the most controversial bioethical issue of our time.

Bioethics and the End of Discussion

In early June, President Obama disbanded the President’s Council on Bioethics. According to White House press officer Reid Cherlin, this was because the Council was designed by the Bush administration to be “a philosophically leaning advisory group” that favored discussion over developing a shared consensus. http://www.nytimes.com/2009/06/18/us/politics/18ethics.html?_r=2

Shared consensus? Like the shared consensus about the Mexico City policy, government funding of Embryonic Stem Cell Research for new lines, or taxpayer funded abortions? All this despite the fact that 51% of Americans consider themselves pro-life? By allowing publicly-funded Embryonic Stem Cell Research only on existing lines, President Bush made a decision that nobody was happy with, but at least it was an honest compromise, and given the principle of second effect, an ethically acceptable one.

President Obama will appoint a new bioethics commission, one with a new mandate and that “offers practical policy options,” Mr. Cherlin said.

Practical policy options? Like the ones likely to be given by Obama’s new authoritative committee to expediently promote the license to kill the most innocent and vulnerable? But that is only the start. As the baby boomers bankrupt Social Security, there will be a strong temptation to expand Obama’s mandate to include the aging “useless mouths”. Oregon and the Netherlands have already shown the way—after all, a suicide pill is much cheaper than palliative care, and it’s much more cost-effective to kill patients rather than care for them. (http://www.euthanasia.com/argumentsagainsteuthanasia.html)

Evan Rosa details many problems with Obama’s decision to disband the Council (http://www.cbc-network.org/research_display.php?id=388), but there are additional disturbing implications:

First, democracies are absolutely dependent on discussion. Dictators have always suppressed free discussion on “sensitive” subjects because it is the nature of evil to fear criticism. This has been true here in the United States, too—in the years leading up to the Civil War, Southern senators and representatives tried to squelch all discussion on slavery. Maybe their consciences bothered them.

Second, no matter how well-meaning the participants may be, consensus between metaphysically opposed parties is impossible in some matters (such as the humanity of a baby a few months before he or she is born, the existence of God, consequentialist vs. deontological reasoning, etc.). The only way to get “consensus” in such situations is by exercising the monopoly of force owned by the government.

Third, stopping government-sponsored discussion on bioethics sets a dangerous precedent for the ethics surrounding nanotechnology. There are numerous ethical issues that nanotechnology is raising, and will continue to raise, that desperately require significant amounts of detailed discussion and deep thinking.

Tyrants begin by marginalizing anyone who disagrees with them, calling them hate-mongering obstructionists (or worse). In addition, they will use governmental power to subdue any who dare oppose their policies.

The details of the dismissal of the Council clearly shows this tendency, though the Council members are not acting very subdued. As one of them supposedly put it, “Instead of meeting at seminars, now we’ll be meeting on Facebook.”

On March 9, Obama removed restrictions on federal funding for research on embryonic stem cell lines derived by means that destroy human embryos.

On March 25, ten out of the eighteen members of the Council questioned Obama’s policy (http://www.thehastingscenter.org/Bioethicsforum/Post.aspx?id=3298).

In the second week of June, Obama fired them all.

Could it be that Obama doesn’t want discussion? We can see what happens if someone gives him advice that he doesn’t want.

Oprah Winfrey’s favorite physician Dr. Mehmet Oz, told her and Michael Fox that “the stem cell debate is dead” because “the problem with embryonic stem cells is that [they are]… very hard to control, and they can become cancerous” (http://www.oprah.com/media/20090319-tows-dr-oz-brain). Besides, induced pluripotent cells can become embryonic, thereby negating the very difficult necessity of cloning.

So “harvesting” embryonic stem cells is not only ethically problematic (i.e. wrong), but it is also scientifically untenable. Obama supports it anyway.

Maybe he could fire Oprah.

Tihamer Toth-Fejel, MS
General Dynamics Advanced Information Systems
Michigan Research and Development Center

Unique opportunity to sponsor research investigating an infectious cause and potential treatment for Alzheimer’s disease



Alzheimer’s disease afflicts some 20 million people world-wide, over 5 million people of whom reside in the United States. It is currently the seventh-leading cause of death in the US. The number of people with the disease is predicted to increase by over 50% by 2030. The economic as well as emotional costs are huge, the costs being estimated as more than $148 billion each year (direct and indirect, for of all types of dementia, to Medicare, Medicaid and businesses).

The causes of Alzheimer’s disease are unknown, apart from the very small proportion with familial disease. We are investigating the involvement of infectious agents in the disease, with particular emphasis on the virus that causes oral herpes/cold sores/fever blisters. We discovered that most elderly humans harbour this virus in their brains and that in those (and only those) who possess a certain genetic factor, the virus confers a strong risk of developing Alzheimer’s disease. Also, we found that the virus is directly involved with the characteristic abnormalities seen in the brains of Alzheimer’s disease patients.

There are several treatment possibilities available to combat this virus and all would be suitable candidates as therapies in Alzheimer’s disease. However, much more research is needed before trials of these agents for Alzheimer’s disease in humans can begin.

In these financially difficult times many funding bodies have to prioritise projects based around long established hypotheses. Projects involving new avenues of investigation can receive very positive comments by scientific reviewers, yet are rarely funded, as they almost always appear risky compared with projects largely confirming or expanding existing ideas. Such conservative projects are almost guaranteed to produce useful data, though with modest impact. This situation can mean that research proposals with the potential to transform our understanding of a disease and offer new approaches to its treatment never reach the threshold for funding and are not implemented, even though the potential and quality of the science is acknowledged by reviewers and funding panel.

It appears that our work examining a viral cause for Alzheimer’s disease is in this category. Despite our publishing a large number of potentially very exciting papers on this topic, and despite our research projects being reviewed favourably by scientific referees, few funding panels are prepared to commit resources to fund our work, as by doing so they deny funding to other more straightforward, very low risk projects.

We are therefore actively seeking sponsorship for several projects of varying costs to investigate the interaction of virus and specific genetic factor, the pathways of viral damage in the brain, and the effects of antiviral agents. All the projects would provide significant evidence strengthening the case for trialling antiviral agents in Alzheimer’s disease.

Antiviral agents would inhibit a likely major cause of the disease in contrast to current treatments, which merely inhibit the symptoms.

If any Lifeboat member knows of a company or individual that would be interested in sponsoring some of our research on Alzheimer’s disease then please contact me for further details.

Ruth Itzhaki

Contact details:

[email protected]

Faculty of Life Sciences, Moffat Building, The University of Manchester, Manchester M60 1QD, UK


Further reading:

The Times, London

http://www.timesonline.co.uk/tol/news/uk/health/article5295794.ece

Journal of Pathology
http://www3.interscience.wiley.com/journal/121411445/abstract

The Lancet
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(96)10149-5/abstract


I would gladly email any further information.

The air is buzzing. People are talking about health more than ever before, and it’s good news for patients. Technology is making it possible for patients to take an active role in “participatory medicine”, partnering with their doctors to decide on the best course of action for their health.

Over the next few months, these 6 events will bring together patients, researchers, doctors, and health enthusiasts. Discussions, partnerships, and innovations will emerge. Keep your eye on these, and attend if you can!

1. TEDMED — October 27–30, http://www.tedmed.com
The medical version of the legendary TED conferences. From the TEDMED site: “The fifth in a series created by Marc Hodosh and Richard Saul Wurman, TEDMED celebrates conversations that demonstrate the intersection and connections between all things medical and healthcare related: from personal health to public health, devices to design and Hollywood to the hospital.” This year’s speakers include Dean Kamen, Craig Venter, Sanjay Gupta and Goldie Hawn..

2. Transform — September 13–15, http://centerforinnovation.mayo.edu/transform
A collaborative symposium at The Mayo Clinic Center for Innovation. From the Transform site: “Transform brings together a dynamic group of speakers and participants from inside and outside the health care industry to explore the intersections between human experience, health care delivery and new business models. Join us to imagine and create innovative ways to deliver a better health care experience in a 21st century world.”

3. Health 2.0 — October 6–7, http://www.health2con.com
Next-generation health companies and patient advocates converge. From the Health 2.0 site: “With more than a hundred speakers and hundreds of new healthcare demos and technologies on display on stage and in the exhibit hall, you’ll get a sweeping overview of the ways that information technology and the web are changing healthcare in areas from online search to health focused online communities and social networks.”

4. Web Strategies for Health Communication — July 19–24, http://webstrategiesforhealth.com
A new course by Dr. Lisa Gualtieri at Tufts University School of Medicine. From the Web Strategies site: “The Summer Institute on Web Strategies for Health Communication covers how to develop and implement a Web strategy to drive a health organization’s online presence, specifically the processes for selecting, using, managing, and evaluating the effectiveness of Web technologies for health communication.”

5. Singularity University — July-August, http://singularityu.org
Graduate studies program started by Ray Kurzweil and Peter Diamandis. From the Singularity University site: “Singularity University aims to assemble, educate and inspire a cadre of leaders who strive to understand and facilitate the development of exponentially advancing technologies and apply, focus and guide these tools to address humanity’s grand challenges.” Biotechnology and Medicine are two of the tracks they offer..

6. Regenstrief Conference — Sept 23–35, http://www.regenstrief.org/conferences/2009
An invitation-only unconference, but one to watch. From the Regenstrief site: “The theme for this year’s conference is Open Health Methodologies. Participants include: Clay Shirky (open source), Dr. Roni Zeiger (Google Health), and Mark Surman (Mozilla).”

If you aren’t able to attend, let us know what you think are the most important issues in health today and we’ll make sure to represent your ideas. Good things will come from all the buzz — the future of health care and health research is bright.