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The human trial of plasma dilution started in Russia last week. The lead researcher is checking how the biomarkers of aging will change in response to 110% plasma replacement during the therapy, and the difference between the group with albumin addition and without albumin. The trial is open to both Russian citizens and people from other countries. It is a hybrid model where part of the expenditures is paid by the volunteers, and part is provided by the patron of the research. This model allowed to get the trial started in record time — less than 9 months from conception to the start date.

The research group wants to test plasmapheresis in combination with other longevity therapies next to see if plasma dilution prior to the other therapy can enhance the results.


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Does blood hold the secret to aging? That’s kind of what an ongoing clinical trial in Russia is trying to find out. Previous experiments carried out in aged mice suggest that plasma dilution has positive effects on cognition and neuroinflammation, and now scientists want to see if the procedure can positively impact humans too.

By the way, don’t forget our conference Ending Age-Related Diseases 2021 is coming soon! Follow this link to learn more and get your ticket:
https://www.lifespan.io/ending-age-related-diseases-2021-conference/

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#clinicaltrials #aging #longevity #parabiosis #plasmapheresis #blood #transfusions

The makers of a luxury vehicle billed as a ‘flying motorcycle’ that can travel upwards of 300mph have completed flight testing their first prototype and are ready to take preorders.

Jetpack Aviation envisions its Speeder—a jet-powered, vertical takeoff and landing (VTOL) aircraft—as both a pleasure craft and a mission vehicle well-suited for medical teams and fire and rescue operations.

The company’s P1 prototype has an aluminum chassis and was tethered during recent flight testing in Southern California, where it hit several benchmarks that ‘demonstrated the Speeder’s ability to take-off, climb, hover, yaw and perform slow transitions into forward flight,’ Aerospace Testing International reported.

varying in age between 18 and 88, only 33% of them said they would be willing to take a pill that allowed them to stay alive at their current age.

If you were asked to participate in this survey, would you be willing to take an immortality pill? Would it matter what age you were before taking it?

In this video, Drs Irina and Mike Conboy talk about their theory of why we age and introduce Neutral Blood Exchange, which came from their original parabiosis experiments documented in a 2005 paper.

Our guests today are Drs. Irina and Michael Conboy of the Department of Bioengineering at the University of California Berkeley. their discovery of the rejuvenating effects of young blood through parabiosis in a seminal paper published in Nature in 2005 paved the way for a thriving field of rejuvenation biology. The Conboy lab currently focuses on broad rejuvenation of tissue maintenance and repair, stem cell niche engineering, elucidating the mechanisms underlying muscle stem cell aging, directed organogenesis, and making CRISPR a therapeutic reality.

Papers mentioned in this video.
Plasma dilution improves cognition and attenuates neuroinflammation in old mice.
https://pubmed.ncbi.nlm.nih.gov/33191466/
Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin.
https://pubmed.ncbi.nlm.nih.gov/32474458/
Rejuvenation of aged progenitor cells by exposure to a young systemic environment.
https://pubmed.ncbi.nlm.nih.gov/15716955/

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Great exclusive interview by longevity expert, PhD. Professor, Systems Biology. Director, Chronic Metabolic and Rare Diseases Systems Biology Initiative (ChroMe RaDSBIn) facebook.com/LifetimeTrustnet/posts/1021975448543419


Dr. Ancha Baranova interview on longevity and Covid technologies.

She discovered many biomarkers for chronic liver diseases, cancer and other illnesses, a biosynthesis of the melanin in human adipose, two novel properties of cell-free DNA, and a variety of novel functions for known biomolecules.