Summary: Will gene drive wipe out malaria-causing mosquitoes, or will the genetic technology that ‘spreads like wildfire’ cause a catastrophe? Gene drive raises hopes and fears as a team of scientists funded by the Bill & Melinda Gates Foundation are using it to wipe out the mosquitoes that carry malaria, to eradicate the disease. [This article first appeared on LongevityFacts. Follow us on Reddit | Google+ | Facebook. Author: Brady Hartman.]
In a basement lab at the Imperial College London (ICL), a group of researchers led by Andrew Hammond are on a mission to wipe out malaria. The scientists are funded by the Bill & Melinda Gates Foundation and are using a technology called gene drive – a souped-up form of genetic engineering designed to wipe out the mosquitoes that carry the disease.
The lab contains cages of mosquitoes modified with the gene drive, along with an additional gene that makes their eyes and other body parts glow red under laser light.
Summary: Can a gene fuel obesity? Variants of a gene called ‘ankyrin-B’ – a gene carried by millions of Americans – could cause individuals to put on pounds through no fault of their own. [This article first appeared on LongevityFacts. Follow us on Reddit | Google+ | Facebook. Author: Brady Hartman]
We often attribute obesity to eating too much and exercising too little. However, the evidence is growing that at least some of our weight gain is predetermined by our genes. And if a simple genetic variant causes weight gain, then it’s a prime target for gene editing.
New research from the University of North Carolina suggests that variants in a gene called ankyrin-B, a gene carried by millions of Americans, could cause individuals to gain weight through no fault of their own.
Have you seen the clickbait campaign that focuses on the research of Dr. Steven Gundry. It employs a slimy, photo-tile lure that asks you to turn up your speakers and then hawks a product or service disguised as a breakthrough discovery. These scams force the viewer to stay on the page. Typically, there is no indication of how long the video is, or any way to skip forward,
But often, it is hard to tell if a photo tile is news or clickbait. Big companies like Yahoo and Outbrain intermingle genuine news with marketing scams, teasers and outright fake news into an array of little photos at the end of every feature. This particular clickbait may be a story of a dogged counter-cultural researcher with a genuinely relevant finding. It could be newsworthy…I’m just not sure. Dr. Gundry clearly believes that our health is adversely affected by many of the plant based foods that we thought was healthy, because of a defense mechanism linked to lectin.
Steven Gundry Food Pyramid
Passing judgement on Dr. Gundry’s evolutionary claims and diet recommendations begs for independent clinical studies, or at least the analysis and commentary of scholars in nutrition, gastroenterology and evolution. But, like Robert Atkins and Dean Ornish, Dr. Gundry seems earnest in his research and motives. I don’t think that he is selling anything other than his opinion.
I found web sites and white papers that summarize his research and conclusions without a scammy video. If true, this would be an eye-opener—completely unexpected! While his points fascinate, I don’t have the tools to determine if this may be legit. This certainly merits vetting.
For example, Gundry claims that farmers have selectively reinforced a genetic mutation in cows, which appeared only two thousand years ago—and that this has resulted in a lectin-like protein in milk called Casein A1. (Normal cows make Casein A2, a safe protein). Apparently, the only herds of “normal” cows are on farms in southern Europe. Could this result in food poisoning for the rest of us? Dr. Gundry is pretty convincing that the answer could be “Yes”.
This article is a stub without a conclusion. Rather than passing judgement, I encourage further inquiry. Reader feedback is invited. What do you think about Dr. Gundry’s analysis and claims. Might there be adverse problems associated with many “healthy” vegetables and out of season fruits? Tell me, doctor: Must I give up sun-dried tomato and eggplant?!
This is Philip Raymond’s first post on food and nutrition. More often, he covers Bitcoin, online privacy and quantum physics.
Dr. Aubrey de Grey Summarizes Rejuvenation Research at the MIT Technology Review. To learn more about the work of Dr. Aubrey de Grey and the SENS Foundation visit http://www.sens.org/
Since the dawn of medicine, aging has been doctors’ foremost challenge. Three unsuccessful approaches to conquering it have failed: treating components of age-related ill health as curable diseases, extrapolating from differences between species in the rate of aging, and emulating the life extension that famine elicits in short-lived species. SENS Research Foundation is spearheading the fourth age of anti-aging research: the repair of age-related damage, that is, rejuvenation biotechnology.
The Strategies for Engineered Negligible Senescence (SENS) approach was first proposed in 2002. “Senescence,” here, refers to the actuarial phenomenon—the trend that individuals within a population suffer from an increasing morbidity and mortality rate in (typically exponential) relation to their chronological age. “Negligible” is used in a statistical sense: we consider a level of senescence negligible if no age-related contribution to mortality is statistically demonstrable within a population, given the “background noise” of age-independent mortality (such as unfortunate encounters with motor vehicles). Finally, by “Engineered,” we indicate that this state is achieved by the deliberate application of biomedical therapies, and is not the normal situation. The goal of SENSE is thus unambiguously defined; we seek methods to convert a population experiencing a non-negligible level of senescence into one experiencing a negligible level.
To see how the goal of negligible senescence could be “engineered,” it is useful to consider a situation in which human ingenuity and perseverance has already achieved an analogous result. Motor vehicles experience a process of wear-and-tear essentially similar to organismal aging; the paint flakes, windowpanes chip, rust infiltrates the pipework, and so forth. Nonetheless, as vintage car owners will attest, it is entirely possible to keep one functional for an essentially indefinite period. Critically, this is achieved not by preventing the wear but by repairing the damage that does occur at a rate sufficient to ensure that the function of the machine is never irretrievably compromised.
Summary: Cryonics has long been a non-starter due to technical limitations. A week-old radical proposal by a Russian cryonics firm to freeze people before death, combined with technological advances in Cryopreservation: Also called cryobanking. The process of cooling and storing cells, tissues, or organs at very low or freezing temperatures to save them for future use. Used in cryonics and the storage of reproductive cells in fertility treatments. [Source – NCI].” class=” glossaryLink “cryopreservation are shaking up the cryonics industry. When will cryonics be ready for prime time? [Author: Brady Hartman. This article first appeared on LongevityFacts.com. Follow us on Reddit | Google+ | Facebook. ]
Google’s most famous technologist, Ray Kurzweil, has signed up for cryonics, saying:
“My primary strategy for living through the 21st century and beyond is not to die”
The soft artificial heart was created from silicone using a 3D-printing, lost-wax casting technique; it weighs 390 grams and has a volume of 679 cm3. “It is a silicone monoblock with complex inner structure,” explains Cohrs. This artificial heart has a right and a left ventricle, just like a real human heart, though they are not separated by a septum but by an additional chamber. This chamber is in- and deflated by pressurized air and is required to pump fluid from the blood chambers, thus replacing the muscle contraction of the human heart.
