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Category: bioprinting

Bioprinting has been all over the news in the past several years with headline-worthy breakthroughs like printed human skin, synthetic bones, and even a fully functional mouse thyroid gland.

3D printing paved the way for bioprinting thanks to the printers’ unique ability to recreate human tissue structures; their software can be written to ‘stack’ cells in precise patterns as directed by a digital model, and they can produce tissue in just hours and make numerous identical samples.

Despite the progress in bioprinting, however, more complex human organs continue to elude scientists, and resting near the top of the ‘more complex’ list are the kidneys.

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A woman living on a dialysis machine is grown a new kidney using her own cells. A father struggling with age-related vision loss has his eyesight restored. A soldier suffers extensive burns and has his skin regenerated.

This is a glimpse of the holy grail of regenerative medicine. The ultimate goal of the field is to develop therapies that restore normal function to diseased tissues and organs. Advances in 3D bioprinting, the process of fabricating functional human tissue outside the body in a layer-by-layer fashion, have pushed the envelope on what is considered possible in the field.

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Bioprinting is becoming more sophisticated daily. Students from Munich, Germany, hacked an Ultimaker 2+ to 3D print biomaterials even more efficient. Without a doubt, the yearly iGEM challenge is one of the yearly highlights for students in the field of biology, biochemistry, and biotechnology.

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Humanized organs in gene-edited animals is one potential way medicine can deal with the demand for transplant organs.

One potential avenue for research and to help solve the organ shortage is to modify animals to be closer matched to humans in order to have organs capable of being used for transplant. This short paper is an interesting primer into the subject and touches upon the technical and ethical concerns involved here.

It is one possible solution to the problem, however, 3D bioprinting increases in sophistication and other methods are also being developed that would render this approach needless. Still this is an interesting insight into regenerative medicine and one possible path research might take.

#LifespanIO #aging #crowdfundthecure

http://www.futuremedicine.com/doi/10.2217/rme-2016-0096

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South Korean-based company Rokit is a 3D printing manufacturer we’ve talked about on several occasions before. In February this year, they released Edison Invivo, a tissue engineering and bio-medical research 3D printer that uses a bio ink to produce cell structures in the form of organic tissue.

Now, as a constant innovator, Rokit is back with their latest and also the world first Multi-Use Hybrid Bio 3D printer — Rokit Invivo. What’s exciting is that this awesome bioprinter will be revealed very soon on 30th, September in the Digical Show held by London-based iMakr.

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In Lyon, France, cosmetics company L’Oreal is growing human skin.

Each year, some 60 scientists cultivate 100,000 paper-thin skin samples in nine varieties simulating different ages and ethnicities—and then they test beauty products on them. Read more

By — SingularityHubhttp://cdn.singularityhub.com/wp-content/uploads/2015/04/heart-and-liver-organoids-1000x400.jpg

There’s something almost alchemical going on at the Wake Forest Institute for Regenerative Medicine. Scientists there have genetically transformed skin cells into heart cells and used them to 3D print mini-organs that beat just like your heart. Another darker organoid fused to a mini-heart mimics your liver.

The work, developed by Anthony Atala and his Wake Forest team for the “Body on a Chip” project, aims to simulate bodily systems by microfluidically linking up miniature organs—hearts, livers, blood vessels, and lungs—and testing new drug treatments and chemicals or studying the effects of viruses on them.

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By — 3D Printing Industry3d bioprinter russiaAll of my relatives that work in the medical or scientific field are very quick to “crush” my arguments when I ask them about the possibility of 3D printing functional organs, saying that there is no way to replicate an organ’s complex, multicellular structure. I consider these relatives to be extremely knowledgeable and reliable, but they are mostly doctors and/or researchers who are not directly familiar with additive manufacturing technologies.

On the other hand, 3D Bioprinting Solution’s enthusiasm, as with any other 3D bioprinting venture, is contagious and I know from experience that, with 3D printing nothing is impossible, and nothing can be entirely discarded. The truth probably lies somewhere in the middle: bioprinting complex organs is an extremely difficult feat to achieve, but, sooner or later, it will be done. And 3D Bioprinting Solutions may be the company to do it. Read more