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Damage of healthy intestinal cells is the main disadvantage of radiotherapy leading to the discontinuation and failure of an efficient cancer treatment, potentially causing a quick tumour recurrence. Now, a discovery published in Science by scientists from the Growth Factors, Nutrients and Cancer Group at the Spanish National Cancer Research Centre (CNIO) might be useful to protect healthy intestinal cells from radiation damage. The consequences of their findings in mice might radically change the way humans manage exposure to high levels of radiation; both for cancer research and treatment as well as for other areas like space explorations, nuclear warfare or nuclear accidents.

The Group’s work focuses on URI, a protein whose functions remain not yet fully understood. However, previous studies from the Group have found that abnormal levels of expression of this protein in certain organs can cause cancer. The study now published in Science shows that high levels of URI protein protect mice from radiation-induced intestinal damage, whereas low or no detectable levels of the protein can lead to gastrointestinal syndrome and death.

“The precise functions of URI have not been identified yet,” says Nabil Djouder, Head of the Growth Factors, Nutrients and Cancer Group at CNIO and leader of the study. “Just like pH or temperature, which the organism needs to maintain within a certain range, URI levels must also be kept within a very narrow window to regulate the proper functioning of other proteins. When URI levels are higher or lower than optimal, they may promote or protect against tumour development as well as other diseases, depending on the context.”

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Elon Musk says adding two to four Raptor Engines to the Starship will let it go sub-orbital for 6000 miles at mach 20. This would mean trips like San Francisco to Shanghai or New York to Berlin. Many world cities are within 6000 miles of each other.

Boeing extended range 767s can reach 6000 miles and the newer 777 and 787 have longer ranges.

If SpaceX can determines ways to save 30% on Starship point to point efficiency then they could get to 8000-mile ranges. This might be possible by lightening landing gear and heat shields. They could need less heat shields for sub-orbital only vehicles.

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“We joke that ‘The Martian’ would have been a much more boring movie,” said Justin Kugler, a vice president at Made In Space.

Fifty years after the first men walked on the moon, a new space race is underway, this one for a piece of what Wall Street analysts say could become a $1 trillion global space market. Around the world, companies such as Made In Space are launching — often literally — new products and services, building satellites to provide broadband internet, spaceships to take tourists on zero-gravity rendezvous, and mining equipment to extract minerals from asteroids.

On HoustonChronicle.com: Elon Musk injects ‘X’ factor into space quest with bold vision, mixed track record.

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Excited about the impending delivery robot revolution? If so, you need to know about Starship Technologies, the company which kickstarted the whole thing. Founded by two of the original creators of Skype, Starship is poised to change the world of deliveries. Here’s what you need to know.

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PASADENA, Calif. — With congressional funding and industry support, nuclear thermal propulsion technology is making progress for potential use on future NASA deep space missions, although how it fits into the agency’s exploration architectures remains uncertain.

The House Appropriations Committee approved May 22 a commerce, justice and science (CJS) appropriations bill that offers $22.3 billion for NASA. That funding includes $125 million for nuclear thermal propulsion development within the agency’s space technology program, compared to an administration request for no funding.

“The bill’s investment in nuclear thermal propulsion is critical as NASA works towards the design of a flight demonstration by 2024,” said Rep. Robert Aderholt (R-Ala.), ranking member of the CJS appropriations subcommittee, during that subcommittee’s markup of the bill May 17. He offered similar comments in support of that project at the full committee markup.

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Relativity Space is working to 3D print the Terran 1 rocket in 60 days using laser printing and direct energy deposition. They will have a test flight in 2020 and will have commercial flights in 2021.

They use proprietary materials which are custom designed for printing. They are using stronger alloys designed to take advantage of Stargate’s printing physics. They have highly reliable materials for printing rocket structures and are using an in-house metallurgy and material characterization lab.

Terran 1 Baseline:

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Astronomers have carried out a multiwavelength investigation of a pulsar wind nebula (PWN), designated DA 495, to unveil its mysterious physical nature. Results of the study, based on observations using HAWC and VERITAS ground-based observatories as well as NASA’s NuSTAR spacecraft, are presented in a paper published May 17 on arXiv.org.

Pulsar wind nebulae (PWNe) are nebulae powered by the wind of a pulsar. Pulsar wind is composed of charged particles; when it collides with the pulsar’s surroundings, in particular with the slowly expanding supernova ejecta, it develops a PWN.

Particles in PWNe lose their energy to radiation and become less energetic with distance from the central pulsar. Multiwavelength studies of these objects, including X-ray observations, especially using spatially-integrated spectra in the X-ray band, have the potential of uncovering important information about particle flow in these nebulae. This could unveil important insights into the nature of PWNe in general.

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Scientists from Ireland and France today [Thursday 23rd May] announced a major new finding about how matter behaves in the extreme conditions of the Sun’s atmosphere.

The scientists used large radio telescopes and ultraviolet cameras on a NASA spacecraft to better understand the exotic but poorly understood “fourth state of matter”. Known as plasma, this matter could hold the key to developing safe, clean and efficient nuclear energy generators on Earth. The scientists published their findings in the leading international journal Nature Communications.

Most of the matter we encounter in our everyday lives comes in the form of solid, liquid or gas, but the majority of the Universe is composed of plasma — a highly unstable and electrically charged fluid. The Sun is also made up of this plasma.

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CAMBRIDGE, MA—Draper is part of five teams selected by NASA recently to conduct studies and produce prototypes of human landers for the agency’s Artemis lunar exploration program. The NASA contracts, which carry a potential value of up to $45.5M, further the agency’s goal to put American women and men on the Moon by 2024 as a step toward establishing sustainable missions by 2028.

When the space agency signaled its intention to partner with American companies on the development of a human landing system in 2018, Draper—with a heritage in human space exploration—participated successfully in the solicitation process in partnership with the five companies. The formal solicitation, to be issued at a later date, will provide the requirements for lander development and a 2024 human lunar landing.

According to NASA, the contracts are intended to “transport astronauts in a human landing system that includes a transfer element for the journey from the lunar Gateway to low-lunar orbit, a descent element to carry them to the surface and an ascent element to return them to the Gateway.”

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