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Coming soon: Advanced brain monitoring “while subjects make natural movements, including head nodding, stretching, drinking and playing a ball game.”


Credit: University of Nottingham ___ This Brain Scanner Is Way Smaller Than fMRI but Somehow 1,000% Creepier (Gizmodo): “It may look like something befitting Halloween’s Michael Myers, but the device pictured above is actually a breakthrough in neuroscience—a portable, wearable brain scanner that can monitor neural.

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In summary — “I am cautiously optimistic about the promise of tDCS; cognitive training paired with tDCS specifically could lead to improvements in attention and memory for people of all ages and make some huge changes in society. Maybe we could help to stave off cognitive decline in older adults or enhance cognitive skills, such as focus, in people such as airline pilots or soldiers, who need it the most. Still, I am happy to report that we have at least moved on from torpedo fish” smile


In 47 CE, Scri­bo­nius Largus, court physi­cian to the Roman emper­or Claudius, described in his Com­po­si­tiones a method for treat­ing chron­ic migraines: place tor­pe­do fish on the scalps of patients to ease their pain with elec­tric shocks. Largus was on the right path; our brains are com­prised of elec­tri­cal sig­nals that influ­ence how brain cells com­mu­ni­cate with each oth­er and in turn affect cog­ni­tive process­es such as mem­o­ry, emo­tion and attention.

The sci­ence of brain stim­u­la­tion – alter­ing elec­tri­cal sig­nals in the brain – has, need­less to say, changed in the past 2,000 years. Today we have a hand­ful of tran­scra­nial direct cur­rent stim­u­la­tion (tDCS) devices that deliv­er con­stant, low cur­rent to spe­cif­ic regions of the brain through elec­trodes on the scalp, for users rang­ing from online video-gamers to pro­fes­sion­al ath­letes and peo­ple with depres­sion. Yet cog­ni­tive neu­ro­sci­en­tists are still work­ing to under­stand just how much we can influ­ence brain sig­nals and improve cog­ni­tion with these techniques.

Brain stim­u­la­tion by tDCS is non-inva­sive and inex­pen­sive. Some sci­en­tists think it increas­es the like­li­hood that neu­rons will fire, alter­ing neur­al con­nec­tions and poten­tial­ly improv­ing the cog­ni­tive skills asso­ci­at­ed with spe­cif­ic brain regions. Neur­al net­works asso­ci­at­ed with atten­tion con­trol can be tar­get­ed to improve focus in peo­ple with atten­tion deficit-hyper­ac­tiv­i­ty dis­or­der (ADHD). Or peo­ple who have a hard time remem­ber­ing shop­ping lists and phone num­bers might like to tar­get brain areas asso­ci­at­ed with short-term (also known as work­ing) mem­o­ry in order to enhance this cog­ni­tive process. How­ev­er, the effects of tDCS are incon­clu­sive across a wide body of peer-reviewed stud­ies, par­tic­u­lar­ly after a sin­gle ses­sion. In fact, some experts ques­tion whether enough elec­tri­cal stim­u­la­tion from the tech­nique is pass­ing through the scalp into the brain to alter con­nec­tions between brain cells at all.

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Scientists found that neurons in mammalian brains were capable of producing photons of light, or “Biophotons”!

The photons, strangely enough, appear within the visible spectrum. They range from near-infrared through violet, or between 200 and 1,300 nanometers.

Scientists have an exciting suspicion that our brain’s neurons might be able to communicate through light. They suspect that our brain might have optical communication channels, but they have no idea what could be communicated.

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Elon Musk’s neurotechnology startup Neuralink filed for permits to build an in-house machine shop and a biological testing laboratory for its facility in San Francisco last year.

The documentation on the company’s 2017 permits was retrieved by Gizmodo, which was able to access Neuralink’s public records. An excerpt of a letter submitted by Neuralink executive Jared Birchall on February 2017 to the city’s planning department gives some clues about the company’s plans for the facility’s proposed machine shop and animal testing lab.

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(credit: Getty)

A revolutionary new theory contradicts a fundamental assumption in neuroscience about how the brain learns. According to researchers at Bar-Ilan University in Israel led by Prof. Ido Kanter, the theory promises to transform our understanding of brain dysfunction and may lead to advanced, faster, deep-learning algorithms.

A biological schema of an output neuron, comprising a neuron’s soma (body, shown as gray circle, top) with two roots of dendritic trees (light-blue arrows), splitting into many dendritic branches (light-blue lines). The signals arriving from the connecting input neurons (gray circles, bottom) travel via their axons (red lines) and their many branches until terminating with the synapses (green stars). There, the signals connect with dendrites (some synapse branches travel to other neurons), which then connect to the soma. (credit: Shira Sardi et al./Sci. Rep)

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In a paper published on March 15, 2018, in the journal Science, Stanford researchers led by Dr. Dena Leeman showed that intracellular protein aggregates accumulate within the lysosomes of neural stem cells that were previously thought not to suffer from this problem [1].

Intracellular waste disposal 101

Dysfunctional proteins and organelles within a cell constitute intracellular waste that the cell needs to dispose of. To do so, the cell may avail itself of proteasomes and lysosomes. Proteasomes are protein complexes that, with the help of enzymes, break down other, unnecessary proteins into shorter amino acids that can then be recycled to build new, useful proteins. Proteasomes are found within the cell nucleus and in the cytosol—the aqueous solution in which everything in a cell floats. The discovery of proteasomes happened later than that of lysosomes, which, for a while, were thought to be the only cellular waste management systems.

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Https://paper.li/e-1437691924#/


In the natural world, intelligence takes many forms. It could be a bat using echolocation to expertly navigate in the dark, or an octopus quickly adapting its behavior to survive in the deep ocean. Likewise, in the computer science world, multiple forms of artificial intelligence are emerging — different networks each trained to excel in a different task. And as will be presented today at the 25th annual meeting of the Cognitive Neuroscience Society (CNS), cognitive neuroscientists increasingly are using those emerging artificial networks to enhance their understanding of one of the most elusive intelligence systems, the human brain.

“The fundamental questions cognitive neuroscientists and computer scientists seek to answer are similar,” says Aude Oliva of MIT. “They have a complex system made of components — for one, it’s called neurons and for the other, it’s called units — and we are doing experiments to try to determine what those components calculate.”

In Oliva’s work, which she is presenting at the CNS symposium, neuroscientists are learning much about the role of contextual clues in human image recognition. By using “artificial neurons” — essentially lines of code, software — with neural network models, they can parse out the various elements that go into recognizing a specific place or object.

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