Scientists found a way to tap into a brain region called the cingulum and activate unbridled joy.
Category: neuroscience
In a recent study in mice, researchers found a way to deliver specific drugs to parts of the body that are exceptionally difficult to access. Their Y-shaped block catiomer (YBC) binds with certain therapeutic materials forming a package 18 nanometers wide. The package is less than one-fifth the size of those produced in previous studies, so it can pass through much smaller gaps. This allows YBCs to slip through tight barriers in cancers of the brain or pancreas.
The fight against cancer is fought on many fronts. One promising field is gene therapy, which targets genetic causes of diseases to reduce their effect. The idea is to inject a nucleic acid-based drug into the bloodstream—typically small interfering RNA (siRNA)—which binds to a specific problem-causing gene and deactivates it. However, siRNA is very fragile and needs to be protected within a nanoparticle or it breaks down before reaching its target.
“siRNA can switch off specific gene expressions that may cause harm. They are the next generation of biopharmaceuticals that could treat various intractable diseases, including cancer,” explained Associate Professor Kanjiro Miyata of the University of Tokyo, who jointly supervised the study. “However, siRNA is easily eliminated from the body by enzymatic degradation or excretion. Clearly a new delivery method was called for.”
How unaware things became aware.
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Now, a pair of research papers published the week of April 22 from the University of Washington — one in the Journal of Neuroscience, the other in the Proceedings of the National Academy of Sciences — use functional MRI to identify two differences in the brains of blind individuals that might be responsible for their abilities to make better use of auditory information.
“There’s this idea that blind people are good at auditory tasks, because they have to make their way in the world without visual information. We wanted to explore how this happens in the brain,” said Ione Fine, a UW professor of psychology and the senior author on both studies.
Instead of simply looking to see which parts of the brain were most active while listening, both studies examined the sensitivity of the brain to subtle differences in auditory frequency.
Graphene quantum dots drawn from common coal may be the basis for an effective antioxidant for people who suffer traumatic brain injuries, strokes or heart attacks.
Their ability to quench oxidative stress after such injuries is the subject of a study by scientists at Rice University, the Texas A&M Health Science Center and the McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth).
Quantum dots are semiconducting materials small enough to exhibit quantum mechanical properties that only appear at the nanoscale.
German scientists create see-through ORGANS in a step toward 3D-printed parts that could be transplanted in the human body…
Researchers in Germany have created transparent human organs using a new technology that could pave the way to print three-dimensional body parts such as kidneys for transplants.
Scientists led by Ali Erturk at Ludwig Maximilians University in Munich have developed a technique that uses a solvent to make organs such as the brain and kidneys transparent.
The organ is then scanned by lasers in a microscope that allows researchers to capture the entire structure, including the blood vessels and every single cell in its specific location.
By Michael Le Page
People with incurable melanomas and brain or breast cancers are to get injections of tumour-fighting viruses.
The trial will test the safety of a virus that has been engineered to shrink tumours – an approach that holds promise for a range of cancers, including deadly brain tumours.