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In this video, Drs Irina and Mike Conboy talk about their theory of why we age and introduce Neutral Blood Exchange, which came from their original parabiosis experiments documented in a 2005 paper.

Our guests today are Drs. Irina and Michael Conboy of the Department of Bioengineering at the University of California Berkeley. their discovery of the rejuvenating effects of young blood through parabiosis in a seminal paper published in Nature in 2005 paved the way for a thriving field of rejuvenation biology. The Conboy lab currently focuses on broad rejuvenation of tissue maintenance and repair, stem cell niche engineering, elucidating the mechanisms underlying muscle stem cell aging, directed organogenesis, and making CRISPR a therapeutic reality.

Papers mentioned in this video.
Plasma dilution improves cognition and attenuates neuroinflammation in old mice.
https://pubmed.ncbi.nlm.nih.gov/33191466/
Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin.
https://pubmed.ncbi.nlm.nih.gov/32474458/
Rejuvenation of aged progenitor cells by exposure to a young systemic environment.
https://pubmed.ncbi.nlm.nih.gov/15716955/

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Health claims Disclosure: Information provided on this video is not a substitute for direct, individual medical treatment or advice. Please consult with your doctor first. Products or services mentioned in this video are not a recommendation.

Disclosure: Some of the links provided are affiliate links. Although we may receive a small commission from the affiliate, the cost of the product for you will always be the same, or often discounted. Thank you for supporting our channel.

Audio Copyright Disclaimer:
Please note that we have full authorization to the music that we used in our videos as they were created using the service WeVideo which provides the rights to the music. The rights are detailed in the terms of use that can be reviewed here https://www.wevideo.com/terms-of-use and any following inquiries should be addressed to [email protected].
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The radar-like scan moves clockwise emanating from the center point to produce pitch. Light that is further from the center is heard as higher pitches while brighter light is louder. The X-rays are represented by a harsher sound, while the visible-light data sound smoother.

Credit: NASA/CXC/SAO/K.Arcand, SYSTEM Sounds.

Emotion regulation is an essential aspect of mental health and wellbeing. In fact, past studies have found associations between poor emotion regulation and several psychiatric disorders, including bipolar disorder, borderline personality disorder and complex post-traumatic stress disorder (PTSD).

During their everyday life, humans can regulate their negative emotions in different ways, most of which do not require any conscious cognitive engagement. For instance, they might take a bath, step outside for fresh air or listen to .

Researchers at Radboud University Nijmegen in The Netherlands, the Norwegian University of Science and Technology (NTNU), and University Hospital Aachen, Germany have recently carried out a study aimed at investigating the effects of a short-term on implicit emotion regulation. Their paper, published in BMC Neuroscience, specifically examined whether musical training helped people to reduce the negative emotions elicited by unpleasant or disgusting odors.

These spring-loaded screws turn your entire drywall into a sound deadening structure that can reduce perceived noise levels by nearly half. They’re pricey for screws, says the Swedish scientist behind them, but very cheap for sound insulation. Known as the Revolutionary Sound Absorbing Screw (or the Sound Screw for short), the device was created by a team at Malmö University, led by senior lecturer Håkan Wernersson. It consists of a threaded section at the bottom, a coil spring in the middle, and a section with a flat head at the top.


Nobody likes hearing their neighbors’ music, TV shows or loud conversations. Soundproof wall materials, however, can be quite thick and expensive. Swedish scientists have developed a thinner, less costly alternative, in the form of a spring-loaded sound-damping screw.

Known as the Revolutionary Sound Absorbing Screw (or the Sound Screw for short), the device was created by a team at Malmö University, led by senior lecturer Håkan Wernersson. It consists of a threaded section at the bottom, a coil spring in the middle, and a section with a flat head at the top.

The screw is inserted into a hole drilled through a drywall panel and into the underlying wooden joist. It is then turned until its threaded section is all the way into the wood, and its head is sitting flush against the outside surface of the drywall. The spring forms of a gap of a few millimeters between the joist and the drywall’s underside.

The Gist: They think they can start wider human trials soon which would last 2 years then have a product in 3 to 4 years.


In this video, Drs Irina and Mike Conboy talk how TPE, therapeutic plasma exchange is already available as an FDA approved procedure and the plans to extend the usage to include more age related diseases. We also discuss the company that they have formed IMU

Our guests today are Drs. Irina and Michael Conboy of the Department of Bioengineering at the University of California Berkeley. their discovery of the rejuvenating effects of young blood through parabiosis in a seminal paper published in Nature in 2005 paved the way for a thriving field of rejuvenation biology. The Conboy lab currently focuses on broad rejuvenation of tissue maintenance and repair, stem cell niche engineering, elucidating the mechanisms underlying muscle stem cell aging, directed organogenesis, and making CRISPR a therapeutic reality.

Papers mentioned in this video.
Plasma dilution improves cognition and attenuates neuroinflammation in old mice.
https://pubmed.ncbi.nlm.nih.gov/33191466/
Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin.
https://pubmed.ncbi.nlm.nih.gov/32474458/
Rejuvenation of aged progenitor cells by exposure to a young systemic environment.
https://pubmed.ncbi.nlm.nih.gov/15716955/

************************************************************
Health claims Disclosure: Information provided on this video is not a substitute for direct, individual medical treatment or advice. Please consult with your doctor first. Products or services mentioned in this video are not a recommendation.

Disclosure: Some of the links provided are affiliate links. Although we may receive a small commission from the affiliate, the cost of the product for you will always be the same, or often discounted. Thank you for supporting our channel.

Audio Copyright Disclaimer:
Please note that we have full authorization to the music that we used in our videos as they were created using the service WeVideo which provides the rights to the music. The rights are detailed in the terms of use that can be reviewed here https://www.wevideo.com/terms-of-use and any following inquiries should be addressed to [email protected].
*****************************************************************
If you would like to support our channel, we’d love a coffee…thank you! https://www.buymeacoffee.com/mhealthspan

In this video, Drs Irina and Mike Conboy talk about the procedure of Neutral Blood Exchange. How it is done and how much blood of the blood is exchanged.

Our guests today are Drs. Irina and Michael Conboy of the Department of Bioengineering at the University of California Berkeley. their discovery of the rejuvenating effects of young blood through parabiosis in a seminal paper published in Nature in 2005 paved the way for a thriving field of rejuvenation biology. The Conboy lab currently focuses on broad rejuvenation of tissue maintenance and repair, stem cell niche engineering, elucidating the mechanisms underlying muscle stem cell aging, directed organogenesis, and making CRISPR a therapeutic reality.

Papers mentioned in this video.
Plasma dilution improves cognition and attenuates neuroinflammation in old mice.
https://pubmed.ncbi.nlm.nih.gov/33191466/
Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin.
https://pubmed.ncbi.nlm.nih.gov/32474458/
Rejuvenation of aged progenitor cells by exposure to a young systemic environment.
https://pubmed.ncbi.nlm.nih.gov/15716955/

************************************************************
Health claims Disclosure: Information provided on this video is not a substitute for direct, individual medical treatment or advice. Please consult with your doctor first. Products or services mentioned in this video are not a recommendation.

Audio Copyright Disclaimer:
Please note that we have full authorization to the music that we used in our videos as they were created using the service WeVideo which provides the rights to the music. The rights are detailed in the terms of use that can be reviewed here https://www.wevideo.com/terms-of-use and any following inquiries should be addressed to [email protected].
*****************************************************************
If you would like to support our channel, we’d love a coffee…thank you! https://www.buymeacoffee.com/mhealthspan.

#BoodPlasmaDilution #Conboy #Rejuvenation #IrinaConboy #UCBerkeley #Tissue #NBE #CRISPR #youngbloodplasma #stemcell #organogenesis #ConboyLab #aging #longevity #anti-aging #Healthspan #modernhealthspan

According to recent Occupational Safety and Health Administration data, workers at Amazon fulfillment centers were seriously injured about twice as often as employees in other warehouses. To improve workplace safety, Amazon has been increasing its investment in robotic helpers to reduce injuries among its employees. With access granted for the first time ever, “Sunday Morning” correspondent David Pogue visited the company’s secret technology facility near Seattle to observe some of the most advanced warehouse robots yet developed, and to experience how high-tech tools are being used to aid human workers.

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This product came out months ago with some shocking numbers as to effect. But those effects were in mice tests. 10–20% increase in lifespan and 55% increase in healthspan. It is AKG, Rejuvant, it’s a product you can buy now. There will be a part 2 of this interview so I hope to hear about human data.


Here we present an interview with Tom Weldon the founder and CEO of Ponce de Leon Health, which makes Rejuvant a Calcium AKG based supplement. In this video Tom talks through the process and reasons for selecting CaAKG. He also talks about some of the other results that they found in their tests, especially with respect to mixing different supplements and their combined effects.

This it part 1 of a two part series. In part 2 we talk about his personal experience and on going clinical trials. With that let me start the interview.

Links to Rejuvant.
https://www.rejuvant.com/
Ponce de Leon Health.
https://pdlhealth.com/

The paper from the Buck institute mentioned in the call.
Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice.
https://pubmed.ncbi.nlm.nih.gov/32877690/

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If you would like to support our channel, we’d love a coffee…thank you! https://www.buymeacoffee.com/mhealthspan.

Health claims Disclosure: Information provided on this video is not a substitute for direct, individual medical treatment or advice. It is the responsibility of you and your healthcare providers to make all decisions regarding your health. Products or services mentioned in this video are not a recommendation or medical advice.

Audio Copyright Disclaimer:
Please note that we have full authorization to the music that we used in our videos as they were created using the service WeVideo which provides the rights to the music. The rights are detailed in the terms of use that can be reviewed here https://www.wevideo.com/terms-of-use and any following inquiries should be addressed to [email protected].

Signals can be amplified by an optimum amount of noise, but this so-called stochastic resonance is a rather fragile phenomenon. Researchers at AMOLF were the first to investigate the role of memory for this phenomenon in an oil-filled optical microcavity. The effects of slow non-linearity (i.e. memory) on stochastic resonance were never considered before, but these experiments suggest that stochastic resonance becomes robust to variations in the signal frequency when systems have memory. This has implications in many fields of physics and energy technology. In particular, the scientists numerically show that introducing slow non-linearity in a mechanical oscillator harvesting energy from noise can increase its efficiency by tenfold. They published their findings in Physical Review Letters on May 27th.

It is not easy to concentrate on a difficult task when two people are having a loud discussion right next to you. However, complete silence is often not the best alternative. Whether it is some soft music, remote traffic noise or the hum of people chatting in the distance, for many people, an optimum amount of noise enables them to concentrate better. “This is the human equivalent of stochastic resonance,” says AMOLF group leader Said Rodriguez. “In our scientific labs stochastic resonance happens in non-linear systems that are bistable. This means that, for a given input, the output can switch between two possible values. When the input is a periodic signal, the response of a non-linear system can be amplified by an optimum amount of noise using the stochastic resonance condition.”