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In his most recent paper “Reducing the Risk of Human Extinction,” SAB member Jason G. Matheny approached the topic of human extinction from what is unfortunately a somewhat unusual angle. Jason examined the cost effectiveness of preventing humanity’s extinction due to a catastrophic asteroid impact.

Even with some rather pessimistic assumptions, his calculations showed a pretty convincing return on investment. For only about US$ 2.50 per life year saved, Matheny predicts that we could mitigate the risk of humanity being killed off by a large asteroid. Maybe it’s just me, but it sounds pretty compelling.

Matheny also made a very good point that we all should ponder when we consider how our charitable giving and taxes gets spent. “We take extraordinary measures to protect some endangered species from extinction. It might be reasonable to take extraordinary measures to protect humanity from the same.”

For more coverage on this important paper please see the October 2007 issue of Risk Analysis and a recent edition of Nature News.

In a recent conversation on our discussion list, Ben Goertzel, a rising star in artificial intelligence theory, expressed skepticism that we could keep a “modern large-scale capitalist representative democracy cum welfare state cum corporate oligopoly” going for much longer.

Indeed, our complex civilization currently does seem to be under a lot of stress.

Lifeboat Foundation Scientific Advisory Board member and best-selling author David Brin’s reply was quite interesting.

David writes:

* THE UNLIKELINESS OF A POSITIVE SUM SOCIETY

Today’s “modern large-scale capitalist representative democracy cum welfare state cum corporate oligopoly” works largely because the systems envisioned by John Locke and Adam Smith have burgeoned fantastically, producing synergies in highly nonlinear ways that another prominent social philosopher — Karl Marx — never imagined. Ways that neither Marx nor the ruling castes of prior cultures even could imagine.

Through processes of competitive creativity and reciprocal accountability, the game long ago stopped being zero-sum (I can only win if you lose) and became prodigiously positive-sum. (We all win, though I’d still like to win a little more than you.) (See Robert Wright’s excellent book “Non-Zero”.)

Yes, if you read over the previous paragraph, I sound a lot like some of the boosters of FIBM or Faith In Blind Markets… among whom you’ll find the very same neocons and conspiratorial kleptocrats who I accuse of ruining markets! Is that a contradiction?

Not at all. Just as soviet commissars recited egalitarian nostrums, while relentlessly quashing freedom in the USSR, many of our own right-wing lords mouth “pro-enterprise” lip service, while doing everything they can to cheat and foil competitive markets. To kill the golden goose that gave them everything.

The problem is that our recent, synergistic system has always had to push uphill against a perilous slope of human nature. The Enlightenment is just a couple of centuries old. Feudalism/tribalism had uncountable millennia longer to work a selfish, predatory logic into our genes, our brains. We are all descended from insatiable men, who found countless excuses for cheating, expropriating the labor of others, or preserving their power against challenges from below. Not even the wisest of us can guarantee we’d be immune from temptation to abuse power, if we had it.

Some, like George Washington, have set a pretty good example. They recognize these backsliding trends in themselves, and collaborate in the establishment of institutions, designed to let accountability flow. Others perform lip-service, then go on to display every dismal trait that Karl Marx attributed to shortsighted bourgeois “exploiters.”

Indeed, it seems that every generation must face this ongoing battle, between those who “get” what Washington and many others aimed for — the positive-sum game — and rationalizers who are driven by our primitive, zero-sum drives. A great deal is at stake, at a deeper level that mere laws and constitutions. Moreover, if the human behavior traits described by Karl Marx ever do come roaring back, to take hold in big ways, then so might some of the social scenarios that he described.

* SHOULD WE — SERIOUSLY — HAVE A FRESH LOOK AT OLD KARL MARX?

Do you, as an educated 21st Century man or woman, know very much about the controversy that transfixed western civilization for close to a century and a half? A furious argument, sparked by a couple of dense books, written by a strange little bearded man? Or do you shrug off Marx as an historical oddity? Perhaps a cousin of Groucho?

Were our ancestors — both those who followed Marx and those who opposed him — stupid to have found him interesting or to have fretted over the scenarios he foretold?

I often refer to Marx as the greatest of all science fiction authors, because — while his long-range forecasts nearly all failed, and some of his premises (like the labor theory of value) were pure fantasy — he nevertheless shed heaps of new light and focused the attention of millions upon many basics of both economics and human nature. As a story-spinner, Marx laid down some “if this goes on” thought-experiments that seemed vividly plausible to people of his time, and for a century afterwards. People who weren’t stupid. People who were, in fact, far more intimate with the consequences of social stratification than we have been, in the latest, pampered generation.

As virtually the inventor of the term “capitalism,” Marx ought to be studied (and criticized) by anyone who wants to understand our way of life.

What’s been forgotten, since the fall of communism, is that the USSR’s ‘experiment’ was never even remotely “Marxism.” And, hence, we cannot simply watch “The Hunt For Red October” and then shrug off the entire set of mental and historical challenges. By my own estimate, he was only 50% a deluded loon — a pretty good ratio, actually. (I cannot prove that I’m any better!) The other half was brilliant (ask any economist) and still a powerful caution. Moreover, anyone who claims to be a thinker about our civilization should be able to argue which half was which.

Marx’s forecasts seem to have failed not because they were off-base in extrapolating the trends of 19th Century bourgeois capitalism. He extrapolated fine. But what he never imagined was that human beings might intelligently perceive, and act to alter those selfsame powerful trends! While living amid the Anglo Saxon Enlightenment, Marx never grasped its potential for self-criticism, reconfiguration and generating positive-sum alternatives.

A potential for changing or outgrowing patterns that he (Marx) considered locked, in stone.

Far from the image portrayed by simplistic FIBM cultists, we did not escape Marx’s scenarios through laissez-faire indolence. In fact, his forecasts failed — ironically — because people read and studied Karl Marx.

* HUMAN NATURE ALWAYS CONSPIRES AGAINST ENLIGHTENMENT

This much is basic. We are all descended from rapacious, insatiable cheaters and (far worse) rationalizers. Every generation of aristocrats (by whatever surface definition you use, from soviet nomenklatura, theocrats, or royalty to top CEOs) will come up with marvelous excuses for why they should be allowed to go back to oligarchic rule-by-cabal and “guided allocation of resources” (GAR), instead of allowing open competition/cooperation to put their high status under threat. Indeed, those who most stridently tout faith in blind markets are often among the worst addicts of GAR.

In particular, it is the most natural thing in the world for capital owners and GAR-masters to behave in the way that Karl Marx modeled. His forecast path of an ever-narrowing oligarchy — followed ultimately by revolution — had solid historical grounding and seemed well on its way to playing out.

What prevented it from happening — and the phenomenon that would have boggled poor old KM — was for large numbers of western elites and commonfolk to weigh alternatives, to see these natural human failure modes, and to act intelligently against them. He certainly never envisioned a smart society that would extend bourgeois rights and social mobility to the underclasses. Nor that societies might set up institutions that would break entirely from his model, by keeping things open, dynamic, competitive, and reciprocally accountable, allowing the nonlinear fecundity of markets and science and democracy to do their positive-sum thing.

In his contempt for human reasoning ability (except for his own), Marx neglected to consider that smart men and women would actually read his books and decide to remodel society, so that his scenario would not happen. So that revolution, when it came, would be gradual, ongoing, moderate, lawful, and generally non-confiscatory, especially since the positive sum game lets the whole pie grow, while giving bigger slices to all.

In fact, I think the last ninety years may be partly modeled according to how societies responded to the Marxian meme. First, in 1917, came the outrageously stupid Soviet experiment, which simply replaced Czarist monsters with another clade of oppressors, that mouthed different sanctimonious slogans. Then the fascist response, which was a deadly counter-fever, fostered by even more-stupid European elites. Things were looking pretty bleak.

* THE ENLIGHTENMENT STRIKES BACK

Only then this amazing thing that happened — especially in America — where a subset of wealthy people, like FDR, actually read Marx, saw the potential pathway into spirals of crude capital formation, monopolization, oppression and revolution… and decided to do something about it, by reforming the whole scenario away! By following Henry Ford’s maxim and giving all classes a stake — which also meant ceding them a genuine share of power. A profoundly difficult thing for human beings to do,

Those elites who called FDR a “traitor to his class” were fools. The smart ones knew that he saved their class, and enabled them to enjoy wealth in a society that would be vastly more successful, vibrant, fun, fair, stable, safe and fantastically more interesting.

I believe we can now see the recent attempted putsch by a neocon-kleptocrat aristocratic cabal in broad but simple and on-target context. We now have a generation of wealthy elites who (for the most part) have never read Marx! Who haven’t a clue how chillingly plausible his scenarios might be, if enlightenment systems did not provide an alternative to revolution. And who blithely assume that they are in no danger, whatsoever, of those scenarios ever playing out.

Shortsightedly free from any thought or worry about the thing that fretted other aristocracies — revolution — they feel no compunction or deterrence from trying to do the old/boring thing… giving in to the ancient habit… using influence and power to gather MORE influence and power at the expense of regular people, all with the aim of diminishing the threat of competition from below. And all without extrapolating where it all might lead, if insatiability should run its course.

What we would call “cheating,” they rationalize as preserving and enhancing a natural social order. Rule by those best suited for the high calling of rulership. Those born to it. Or Platonic philosopher kings. Or believers in the right set of incantations.

* REVENGE OF THE DARKSIDE LORDS

Whatever the rationalizations, it boils down to the same old pyramid that failed the test of governance in nearly 100% of previous civilizations, always and invariably stifling creativity while guiding societies to delusion and ruin. Of course, it also means a return to zero-sum logic, zero-sum economics, zero-sum leadership thinking, a quashing of nonlinear synergies… the death of the Enlightenment.

Mind you! I am describing only a fraction of today’s aristocracy of wealth or corporate power. I know half a dozen billionaires, personally, and I’d wager none of them are in on this klepto-raid thing! They are all lively, energetic, modernistic, competitive and fizzing with enthusiasm for a progressive, dynamic civilization. A civilization that’s (after all) been very good to them.

They may not have read Marx (in this generation, who has?) But self-made guys like Bezos and Musk and Page etc share the basic values of an Enlightenment. One in which some child from a poor family may out-compete overprivileged children of the rich, by delivering better goods, innovations or services. And if that means their own privileged kids will also have to work hard and innovate? That’s fine by them! Terrific.

When the chips come down, these better billionaires may wind up on our side, weighing the balance and perceiving that their enlightened, long range self-interest lies with us. With the positive-sum society. Just the way FDR and his smart-elite friends did, in the 1930s… while the dumber half of the aristocracy muttered and fumed.

We can hope that the better-rich will make this choice, when the time comes. But till then, the goodguy (or, at least with-it) billionaires are distracted, busy doing cool things, while the more old-fashioned kind — our would-be lords — are clustering together in tight circles, obeying 4,000 years of ingrained instinct, whispering and pulling strings, appointing each other to directorships, awarding unearned golden parachutes, conniving for sweetheart deals, and meddling in national policy…

…doing the same boring thing that human beings will always do — what you and I would be tempted to do — whenever you mix un-curbed ego with unaccountable privilege, plus a deficit of brains.

Planning for the first Lifeboat Foundation conference has begun. This FREE conference will be held in Second Life to keep costs down and ensure that you won’t have to worry about missing work or school.

While an exact date has not yet been set, we intend to offer you an exciting line up of speakers on a day in the late spring or early summer of 2008.

Several members of Lifeboat’s Scientific Advisory Board (SAB) have already expressed interest in presenting. However, potential speakers need not be Lifeboat Foundation members.

If you’re interested in speaking, want to help, or you just want to learn more, please contact me at [email protected].

What’s the NanoShield you ask? It’s a long-term scientific research project aimed at creating a nanotechnoloigical immune system. You can learn more about it here.

Facebook users — please come join the cause and help fund the Lifeboat Foundation’s NanoShield project.

Not a Facebook user? No worries. By joining the Lifeboat Foundation and making even a small donation you can have a hugely positive impact on humanity’s future well being.

So why not join us?

The inspiration of Help Hookup is actually a comic book called Global Frequency by Warren Ellis. My brother, Alvin Wang, took the idea to startup weekend and they launched the idea this past weekend for hooking up volunteers. It is similar to the concepts of David Brin’s “empowered citizens” and Glenn Reynolds “an army of Davids”. The concepts are compatible with the ideas and causes of the Lifeboat foundation.

Global Frequency was a network of 1,001 people that handled the jobs that the governments did not have the will to handle. I thought that it was a great idea and it would be more powerful with 1,000,001 people or 100,000,001 people. We would have to leave out the killing that was in the comic.

Typhoons, earthquakes, and improperly funded education could all be handled. If there is a disaster, doctors could volunteer. Airlines could provide tickets. Corporations could provide supples. Trucking companies could provide transportation. Etc. State a need, meet the need. No overhead. No waste.

The main site is here it is a way for volunteers to hookup

The helphookup blog is tracking the progress.

University of Pittsburgh researchers injected a therapy previously found to protect cells from radiation damage into the bone marrow of mice, then dosed them with some 950 roentgens of radiation — nearly twice the amount needed to kill a person in just five hours. Nine in 10 of the therapy-receiving mice survived, compared to 58 percent of the control group.

Between 30 and 330 days, there were no differences in survival rates between experiment and control group mice, indicating that systemic MnSOD-PL treatment was not harmful to survival.

The researchers will need to verify whether this treatment would work in humans.

This is part of the early development in the use of genetic modification to increase the biological defences (shields) of people against nuclear, biological and chemical threats. We may not be able to prevent all attacks, so we should improve our toughness and survivability. We should still try to stop the attacks and create the conditions for less attacks.

Robert Freitas, Jr., Lifeboat Foundation Fellow and head of the Lifeboat Foundation’s Nanomedicine Division has won the 2007 Foresight Institute Feynman Prize in Communication.

Dr. Pearl Chin, President of the Foresight Nanotech Institute, said Freitas received the award for “pioneering the study and communication of the benefits to be obtained from an advanced nanomedicine that will be made possible by molecular manufacturing [and for having] worked to develop and communicate a path from our current technology base to a future technology base that will enable advanced nanomedicine.”

Prior to his Feynman Prize win Robert shared the Lifeboat Foundation’s 2006 Guardian Award with technology legend Bill Joy. Freitas and Joy shared the Guardian award for their many years of work on mitigating risks posed by advanced technologies.

Determining the structure of a protein called hemagglutinin on the surface of influenza B is giving researchers at Baylor College of Medicine and Rice University in Houston clues as to what kinds of mutations could spark the next flu pandemic.

This is interesting research and progress in understanding and possibly blocking changes that would lead to pandemics.

In a report that goes online today in the Proceedings of the National Academy of Sciences (PNAS), Drs. Qinghua Wang, assistant professor of biochemistry and molecular biology at BCM, and Jianpeng Ma, associate professor in the same department and their colleagues describe the actual structure of influenza B virus hemagglutinin and compare it to a similar protein on influenza A virus. That comparison may be key to understanding the changes that will have to occur before avian flu (which is a form of influenza A virus) mutates to a form that can easily infect humans, said Ma, who holds a joint appointment at Rice. He and Wang have identified a particular residue or portion of the protein that may play a role in how different types of hemagglutinin bind to human cells.

“What would it take for the bird flu to mutate and start killing people” That’s the next part of our work,” said Ma. Understanding that change may give scientists a handle on how to stymie it.

There are two main forms of influenza virus – A and B. Influenza B virus infects only people while influenza A infects people and birds. In the past, influenza A has been the source of major worldwide epidemics (called pandemics) of flu that have swept the globe, killing millions of people. The most famous of these was the Pandemic of 1918–1919, which is believed to have killed between 20 and 40 million people worldwide. It killed more people than World War I, which directly preceded it.

The Asian flu pandemic of 1957–1958 is believed to have killed as many as 1.5 million people worldwide, and the so-called Hong Kong flu pandemic of 1968–1969 is credited with as many as 1 million deaths. Each scourge was accompanied by a major change in the proteins on the surface of the virus.

The Lifeboat Foundation has the bioshield project

New Scientist reports on a new study by researchers led by Massimiliano Vasile of the University of Glasgow in Scotland have compared nine of the many methods proposed to ward off such objects, including blasting them with nuclear explosions.

The team assessed the methods according to three performance criteria: the amount of change each method would make to the asteroid’s orbit, the amount of warning time needed and the mass of the spacecraft needed for the mission.

The method that came out on top was a swarm of mirror-carrying spacecraft. The spacecraft would be launched from Earth to hover near the asteroid and concentrate sunlight onto a point on the asteroid’s surface.

In this way, they would heat the asteroid’s surface to more than 2100° C, enough to start vaporising it. As the gases spewed from the asteroid, they would create a small thrust in the opposite direction, altering the asteroid’s orbit.

The scientists found that 10 of these spacecraft, each bearing a 20-metre-wide inflatable mirror, could deflect a 150-metre asteroid in about six months. With 100 spacecraft, it would take just a few days, once the spacecraft are in position.

To deflect a 20-kilometre asteroid, about the size of the one that wiped out the dinosaurs, it would take the combined work of 5000 mirror spacecraft focusing sunlight on the asteroid for three or more years.

But Clark Chapman of the Southwest Research Institute in Boulder, Colorado, US, says ranking the options based on what gives the largest nudge and takes the least time is wrongheaded.

The proper way to go about ranking this “is to give weight to adequate means to divert an NEO of the most likely sizes we expect to encounter, and to do so in a controllable and safe manner”, Chapman told New Scientist.

The best approach may be to ram the asteroid with a spacecraft to provide most of the change needed, then follow up with a gravity tractor to make any small adjustments needed, he says.

It is good to have several options for deflection and a survey to detect the specific risks of near earth objects.

A new biosensor developed at the Georgia Tech Research Institute (GTRI) can detect avian influenza in just minutes. In addition to being a rapid test, the biosensor is economical, field-deployable, sensitive to different viral strains and requires no labels or reagents.

This kind of technology could be applied to real time monitoring of other diseases as well.


Photograph of the optical biosensor that is approximately 16 millimeters by 33 millimeters in size. The horizontal purple lines are the channels on the waveguide. Credit: Gary Meek

“We can do real-time monitoring of avian influenza infections on the farm, in live-bird markets or in poultry processing facilities,” said Jie Xu, a research scientist in GTRI’s Electro-Optical Systems Laboratory (EOSL)

The biosensor is coated with antibodies specifically designed to capture a protein located on the surface of the viral particle. For this study, the researchers evaluated the sensitivity of three unique antibodies to detect avian influenza virus.

The sensor utilizes the interference of light waves, a concept called interferometry, to precisely determine how many virus particles attach to the sensor’s surface. More specifically, light from a laser diode is coupled into an optical waveguide through a grating and travels under one sensing channel and one reference channel.

Researchers coat the sensing channel with the specific antibodies and coat the reference channel with non-specific antibodies. Having the reference channel minimizes the impact of non-specific interactions, as well as changes in temperature, pH and mechanical motion. Non-specific binding should occur equally to both the test and reference channels and thus not affect the test results.

An electromagnetic field associated with the light beams extends above the waveguides and is very sensitive to the changes caused by antibody-antigen interactions on the waveguide surface. When a liquid sample passes over the waveguides, any binding that occurs on the top of a waveguide because of viral particle attachment causes water molecules to be displaced. This causes a change in the velocity of the light traveling through the waveguide.