Toggle light / dark theme

This is the oldest and largest art magazine by circulation in the world. For the first time, it has #transhumanism in its search engines. A main task of mine all these years has been spreading that word and concept. My talk at #Moogfest on the Immortality Bus is covered a bit in this story.


L ast month, as bidding was underway at Sotheby’s for what would prove to be a stratospheric Jean-Michel Basquiat sale, Lonnie Holley, a 67-year-old artist who was born in Birmingham, Alabama, and has worked for decades in various folksy and homegrown modes, was preparing to take the stage at a sports bar in Durham, North Carolina. He was sitting at a table in the back, in a place that stank of burgers and beer. An audience of a few dozen had convened for the occasion, though it was hard to distinguish between Holley fans and regular denizens of the Bullpen, a joint next door to the stadium for the beloved local minor-league baseball team, the Durham Bulls. Night-game lights were bright outside. Televisions above the bar showed the Bulls making easy work of the Gwinnett Braves, in town for a weekend series from Georgia. The air was thick and languid in the way it tends to be on a deep, hot Southern summer night.

Holley is a hero to some: as an artist, he has made formidable paintings and sculptures that have been collected by the Souls Grow Deep Foundation and exhibited by museums and institutions all over, and as a musician, he has forged an unforgettable sound with a stirring voice and stewing electronics. For all his accomplishments, though, Holley remains underappreciated—certainly not as known in the worlds of either art or music as he should be.

So first came an introduction. Tim Duffy, the founder of Music Maker Relief Foundation, an organization devoted to preserving musical traditions of the South, took to a microphone and lavished Holley with praise, running down a list of laurels and markers of a legacy still in the making. “Thumbs up for Mother Universe,” Duffy said, thankful for the cosmic conception of an artist he clearly revered.

Read more

Philadelphia, PA, USA / Moscow, Russia — Bioquark, Inc., (www.bioquark.com) a life sciences company focused on the development of novel bio-products for regeneration, disease reversion, and healthy aging, and Moscow based, Lakmus LLC, a diversified investment company with business interests in pharmacies, restaurants, and real estate, announced a multi-disciplinary research collaboration with the FSBI Zakusov Institute of Pharmacology, Russian Academy of Medical Sciences (http://www.academpharm.ru/), and the Pavlov Institute of Physiology of the Russian Academy of Sciences (http://www.infran.ru/), to jointly study the pharmacotherapeutic longevity enhancement properties of its combinatorial regenerative biologic candidates.

“We are very excited about this continued collaboration with Lakmus,” said Ira S. Pastor, CEO, Bioquark Inc. “The disciplined development of our combinatorial biologic candidates (Bioquantines) for healthy longevity enhancement, represents another important step in our continued evolution as a company focused on a broad range of therapeutic products and services in the regenerative healthcare space.”

Throughout the 20th century, natural products formed the basis for a majority of all pharmaceuticals, biologics, and consumer healthcare products used by patients around the globe, generating trillions of dollars of wealth. However, many scientists believe we have only touched the surface with what the natural world, and its range of organisms, which from a health and wellness perspective are much further advanced than human beings, has to teach us.

The integration of a complex set of newer research disciplines, including interkingdom signaling, semiochemical communication, and evolutionary biology, as well as significant recent activity in the areas of the microbiome, are highlighting a myriad of new ways that non-human bio-products can affect the human genome for positive transitions in health and wellness dynamics.

“Bioquark has spent several years studying the natural ability of many species to turn back biological time in order to maintain health, fitness, and survival, developing a broad understanding of the combinatorial biochemical approaches they use to control nested hierarchies of disease (i.e. gene, cell, tissue, organism, environment),” said Dr. Sergei Paylian, Founder, CSO, and President, Bioquark Inc. “This research initiative is one more step in the path in allowing humans to recapture these capabilities to effectively counter our unfortunate progression into aging, disease and degeneration.”

About Bioquark, Inc.

Bioquark Inc. is focused on the development of natural biologic based products, services, and technologies, with the goal of curing a wide range of diseases, as well as effecting complex regeneration. Bioquark is developing both biological pharmaceutical candidates, as well as products for the global consumer health and wellness market segments.

Today live from Cooper Union, NYC, the June edition of Journal Club is being broadcast on our Facebook page at 13:00 EST / 18:00 UK.

We are discussing the recent paper “Common Telomere Changes during In Vivo Reprogramming and Early Stages of Tumorigenesis.” by Blaso et al.

Tune in today and get involved in the discussion. Journal Club is made possible thanks to the support of our Lifespan Heroes.

Read more

Introducing Lifespan Heroes our new campaign.


Here at Lifespan.io we are funding research to help extend healthy human lifespan, supporting nonprofits and companies working to overcome age-related diseases. By becoming a “Lifespan Hero” you can join us in this humanitarian and necessary effort — http://www.lifespan.io/heroes — and help us end age-related diseases for good.

In this video Lifespan.io / LEAF President Keith Comito explains the work Lifespan.io has done thus far in funding research, educating the public, and building a grass roots movement in support of healthy human lifespan, as well as the work that can be done in the future with the support of heroes willing to stand up and fight against the diseases of aging, like Alzheimer’s, heart disease, and cancer, by addressing their shared root causes.

Together we can do this; please join us.

This video is presented by LEAF. Please support our work to overcome the diseases of aging: http://lifespan.io/hero

Read more

If you are not sure why you should support rejuvenation research, or know people who aren’t, this article explains why rejuvenation would be good for you as an individual.


The reasons why rejuvenation would be good for any given individual should be bleeding obvious. However, you’d be surprised how often people think it all boils down to ‘You’d live forever!’—which by the way is not granted and can be a bit of a controversial concept. The real reasons why rejuvenation would be good for you as an individual are the following.

The elderly of today aren’t exactly famous for their good health, nor for their ability to go about their lives easily and without help in even the simplest tasks. Old people have weaker bodies, weaker immune systems, are prey to a number of horrible diseases and chronic pain, and cannot take care of themselves with the same ease as they did when they were young. Pay attention next time you go downtown. You’ll see elderly people walking slowly and with difficulty, perhaps with the aid of a walker or a cane. They can’t hear well and they can’t see well. Climbing the stairs for them feels like more climbing a mountain. A young person can shake off the flu after a few days of discomfort; an old person may well die of the complications of it, because their weak immune system did not do a very good job. This is, in a nutshell, why young people can take care of themselves and old people end up in hospices or have to be watched over by their families.

Read more

Since the moment humans became aware of their existence, they have been haunted by the knowledge that it will inevitably come to an end and the hope to change this unfortunate fate.

This month, during Brain Bar Budapest – Europe’s leading conference on the future – Stephen Cave talked about the four immortality stories we tell ourselves and how they are changing in the context of new scientific discoveries and technological advancements. Stephen Cave spent a decade studying and teaching philosophy, and was awarded his PhD in metaphysics from the University of Cambridge in 2001. He is Executive Director of the Leverhulme Centre for the Future of Intelligence and Senior Research Associate at the University of Cambridge.

Stephen Cave

Read more

Overpopulation is the most common objection people make to developing rejuvenation biotechnology and potentially increasing healthy human lifespan. We take a look at why that is and if the figures support this concern.


Any discussion of rejuvenation biotechnology almost certainly includes the subject of overpopulation and that objection medical advances that directly address the various processes of aging will lead to an overpopulated world. Such dire predictions are a common theme when advances in medicine that could increase human lifespans are concerned.

Overpopulation is a word that gives the simple fact of population growth a negative connotation. It implies that an increase in the number of people will harm our lives in different ways: it might be famine, scarcity of resources, excessive population density, increased risks of infectious diseases, or harm to the environment.

This concern, first raised by the work of 18th century Reverend and scholar Thomas Malthus, has been a constant theme in both popular fiction and early foresights related to population growth. But is it actually well-founded? Let’s take a look at the issues behind these concerns from a scientific point of view.

Read more

Can we live to 1,000? It was outrageous when he said it at ideacity in 2008… and again in 2015. Now he’s back to update us on the incredible progress that has been made toward life extension.

Michael Kramer of Zoomer Radio talks with Aubrey de Grey at ideacity 2017. Aubrey de Grey is an English author and biomedical gerontologist, currently the Chief Science Officer of the SENS Research Foundation. Find out more about ideacity at http://www.ideacity.ca/ideacity-2017/

Read more

LEAF Director Elena Milova recently attended the International Longevity and Cryopreservation Summit in Madrid and gave a talk about effective advocacy and how we can engage better with the public as advocates for rejuvenation biotechnology.

Her talk touches upon effective message delivery as well as the basic principles of teaching, known as the didactic principles.

If we can learn to master this techniques it will help us all become better advocates and champions of rejuvenation biotechnology. Her talk is available below and for those who prefer reading, there is a text version of the main points addressed during the presentation. The presentation slides used in the video are available here or here for pdf.

Read more

Excellent lightning round questions below the audio. Between Dune and Hitchhikers Guide, Liz is indeed a nerd.


In this episode we talk about aging. It’s a condition that everyone experiences and indeed, one thing is certain: when it comes to aging, our condition is terminal. Our guest today is challenging that and fighting aging head on. We’re speaking with Liz Parrish, the CEO of BioViva, a biotech company dedicated to advancing gene and cell therapies to treat the diseases of aging. We dive into her work and learn about the results of the treatment that she received to slow and maybe even reverse the effects of aging.

Liz is a passionate advocate for patient access to these revolutionary treatments, and a couple years ago, Liz decided to take her own medicine – literally. In September 2015, Liz underwent genetic therapy with the aim of slowing and even reversing the effects of aging. She believes that aging should be classified as a disease to open up entirely new and untapped pathways to extend human lives and allow us to be healthier, longer.

Gene therapy to treat aging as a disease. Is this something that will catch on? Should we be tinkering with our own genes in this way? If not, why not? We’re already extending the lives of animals from earthworms to mice – why shouldn’t we work to extend our own lives through applying this technology? But if we do that, will these treatments only be available to the elite and wealthy of our society, or is this something that can benefit all of society by making it available to anyone who wants it?

Read more