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As part of our ongoing series covering the hallmarks of aging, we are taking a look at deregulated nutrient sensing today and how these four pathways regulate metabolism and influence aging.

To understand studies on nutrient sensing in the context of aging, let’s introduce four key protein groups. In this post, we’ll explore the pathways they help control and how they affect aging. These key proteins are IGF-1, mTOR, sirtuins, and AMPK[2]. We call these proteins “nutrient sensing” because nutrient levels influence their activity[2].

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Diagnosis, Advice, and Treatment: This article is intended for informational and educational purposes only and is not a substitute for professional medical advice. Anti-aging therapies are considered experimental and involve extra risks. The information provided in this article should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for the diagnosis and treatment of any and all medical conditions. Call 911 or the equivalent emergency hotline for all medical emergencies. As well, consult a licensed physician before your changing diet, supplement or exercise programs. Photos, External Links & Endorsements: This article is not intended to endorse companies, organizations or products. Links to external websites, depiction/mention of company names or brands, are intended only for illustration and do not constitute endorsements.

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Experts at Tufts University and other organization say the health benefits of coffee vary depending on how you prepare it.


Summary: Which has greater health benefits instant coffee vs. brewed? Experts at Tufts University and other organizations say that the health benefits of coffee vary depending on how you prepare the beverage. [This article first appeared on the website LongevityFacts. Author: Brady Hartman. ]

Does instant have the same health benefits as brewed coffee?

Coffee is not only popular. It’s also a healthy drink.

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Summary: Health organizations recommend keeping high cholesterol levels in check to be healthier. [Author: Brady Hartman – This article first appeared on the website LongevityFacts.]

High cholesterol levels are a silent killer that significantly increases the risk of stroke, kidney disease heart attack, and death. Cholesterol builds up the insides of artery walls, blocking the arteries that feed the brain, heart, kidneys. Treatment is efficient and inexpensive, yet many people walk around with high cholesterol levels, needlessly letting it steal years from their lives.

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The straight poop on fecal transplants. Scientists think fecal transplants help us live longer, healthier lives.

Quote: “Seres Therapeutics is one of the more promising names in poop.”


Here’s the straight poop on fecal transplants, a new medical procedure which physicians use to treat infections. Geroscientists suspect that fecal transplants could help us live longer, healthier lives by giving us a microbiome upgrade. [This report was originally published on LongevityFacts.com. Author: Brady Hartman]

The human microbiome is an invisible world that is only recently coming into focus. The collection of bacteria that inhabit your body is a delicate ecosystem that can crash as you age, travel, or even take a new medication. When it collapses, it can lead to all sorts of distress.

The Business End Of The Poop Industry

Seres Therapeutics is one of the more promising names in poop. The Cambridge biotech company has been trying to transform medicine by harnessing the billions of bacteria in our intestines.

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Summary: People can delay or prevent type 2 diabetes with a healthy diet and exercise. Medications also work but are less effective than lifestyle changes. [This article first appeared on the LongevityFacts.com website. Author: Brady Hartman.]

According to the CDC, the ways to delay or prevent type 2 diabetes include diet, exercise, and in some cases, medications. Don’t take risks with your health – all three of these tactics should only be carried out under the supervision of a qualified physician.

Research shows that some prevention strategies are more successful than others in preventing type 2 diabetes.

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Summary: A wrap-up of the 2017 reports on the search for breakthrough treatments for Alzheimer’s, Parkinson’s disease, and other forms of dementia, showing the advancements made in understanding, treating and preventing these neurodegenerative diseases, including promising therapies in the pipeline. [This article first appeared on the website LongevityFacts.com. Author: Brady Hartman. ]

During 2017, researchers made advances towards understanding what causes Alzheimer’s, Parkinson’s and other forms of dementia. During the year, brain scientists announced they have many promising treatments for dementia in the pipeline. Moreover, researchers have suggested ways to prevent these disabling neurodegenerative diseases.

Here’s a wrap-up of advancements made in understanding, treating and preventing dementia.

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Summary: Researchers say coffee prevents Alzheimer’s and Parkinson’s for those consuming 3 cups daily. The brain health benefits of the beverage seem to differ between decaf and regular coffee. [Author: Brady Hartman. This article first appeared on LongevityFacts.com.]

Perhaps you’ve heard the latest news – the evidence on coffee’s health benefits is increasing every day.

In fact, new research shows that coffee protects your brain, and recent studies show that daily coffee drinkers have a significantly reduced risk of both Alzheimer’s and Parkinson’s diseases.

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