Lifeboat Foundation: Safeguarding Humanity
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Category: life extension

Los Angeles County officials launched a program Wednesday to help locate people with autism, Alzheimer’s disease or dementia who may wander off and go missing.

The program, called L.A. Found, will make use of bracelets that can be tracked through radio frequency by sheriff’s deputies. It will also create a new office, housed within the department of Workforce Development, Aging and Community Services, to coordinate a countywide response when somebody goes missing.

“If you get lost, we will help find you,” county Supervisor Janice Hahn, who championed the initiative, said at a news conference.

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An interview with Methuselah Foundation’s founder David Gobel.

David Gobel is an inventor, philanthropist, futurist, and passionate rejuvenation advocate and supporter; he’s known for co-founding Methuselah Foundation with Dr. Aubrey de Grey and for proposing the intriguing concept of “longevity escape velocity”, but his achievements and successes extend far beyond that. David has kindly granted LEAF a most interesting and detailed interview.

If you’re not familiar with the Methuselah Foundation, it is possibly the oldest organization active in the field of rejuvenation advocacy and support; it also works as an incubator for startups working in rejuvenation research and has helped kickstart many of the projects we talk so much about on our website. If you like, you can find more information on Methuselah Foundation in our older article.

We hope you enjoy Dave’s replies as much as we did!

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Science is advancing rapidly, and the field of aging research is no exception. Our understanding of aging has grown a great deal in the last decade, and we are now reaching the point at which the first therapies that target aging are starting to arrive. Unlike the snake oil of previous years, some of these might actually work; today, we are going to have a look at NAD+ repletion, one such promising therapy.

In the near term, nicotinamide adenine dinucleotide (NAD+) is showing potential for addressing some of the aging processes. NAD+ levels decline significantly during aging in both humans and animals, and studies on old mice have shown that restoring NAD+ levels causes them to look and act like younger mice while increasing their lifespan.

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As technology advances, prospects for increasing the human life span are seemingly everywhere.

But is there a limit to how long humans can live? According to a new study, published today (June 28) in the journal Science, the answer to that question is no. What’s more, the researchers argue that after age 105, the risk of dying each year remains the same.

In 1825, British actuary Benjamin Gompertz proposed that the risk of dying exponentially increases by age, such that a person at age 70 would be at a much higher risk of dying than a 30-year-old. [Extending Life: 7 Ways to Live Past 100].

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In my life as a human, I see clues that evolution on Earth and elsewhere in the cosmos at large is not being pushed from behind in entropic randomness but being pulled forward by complexification, natural selection and other evolutionary forces orchestrated by a strange unseen teleological attractor, in McKenna’s words “the Transcendental Object” at the end of time. One may see significant overlapping ideas between the transhumanist Technological Singularity and the Teilhardian Omega Point. The coming Technological Singularity could unravel one of the deepest mysteries of fractal hyperreality: consciousness alternating from pluralities to singularities and from singularities back to pluralities. We are already immortal, but the forthcoming Syntellect Emergence when your mind is digitized, will preserve some of your organic memories if you so desire, and most importantly, will ensure the continuity of your subjectivity into the higher realms of existence. #LifeboatFoundation

By Alex Vikoulov.

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“If the doors of perception were cleansed then everything would appear to man as it is, Infinite. For man has closed himself up, till he sees all things through narrow chinks of his cavern” –William Blake.

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https://speaker.future.consulting/en/home/search/video/video/the-biological-revolution-how-brain-death-will-be-curable-before-cancer/

LEAF’s August 2018 roundup is out!

We hope August has treated you well—it certainly did so for life extension, as this has been another month full of great news for the field. Don’t be upset with the departure of summer and the arrival of autumn, because little by little, we’re getting close to pushing away the autumn of years.

More investments against aging

The fight against aging is being taken more and more seriously by a growing number of investors, who realize the world-changing potential of effective rejuvenative treatments as well as the great opportunity for profit. Juvenescence Limited, which recently closed a 10-million deal with Ichor Therapeutics‘ Antoxerene, has now announced the purchase of 14.4 million shares of BioTime’s AgeX Therapeutics—a company focused on extending healthy human lifespan—for a total of over $43 million. AgeX’s work focuses on telomerase upregulation and cell therapies, and Juvenescence has invested in AgeX before. The news has been reported and commented on on Fight Aging! as well.

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An extraordinary new anti-ageing technique could see humans live to 150 years old and allow them to regrow their organs by 2020.

Harvard Professor David Sinclair and researchers from the University of New South Wales developed the new process, which involves reprogramming cells.

Dr Sinclair said the technique could allow people to regenerate organs, and even allow paralysis sufferers to move again, with human trials due within two years.

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The ability to reverse ageing is something many people would hope to see in their lifetime. This is still a long way from reality, but in our latest experiment, we have reversed the ageing of human cells, which could provide the basis for future anti-degeneration drugs.

Ageing can be viewed as the progressive decline in bodily function and is linked with most of the common chronic diseases that humans suffer from, such as cancer, diabetes and dementia. There are many reasons why our cells and tissues stop functioning, but a new focus in the biology of ageing is the accumulation of “senescent” cells in the tissues and organs.

Senescent cells are older deteriorated cells that do not function as they should, but also compromise the function of cells around them. Removal of these old dysfunctional cells has been shown to improve many features of ageing in animals such as the delayed onset of cataracts.

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Citi has produced another of its Disruptive Innovations publications, which takes a look at what it considers to be the top ten disruptive technologies. It is a sign of the changing times that anti-aging medicines are number 2 in its list.

1. All-Solid-State Batteries 2. Anti-Aging Medicines 3. Autonomous Vehicle Networks 4. Big Data & Healthcare 5. Dynamic Spectrum Access 6. eSports 7. 5G Technology 8. Floating Offshore Wind Farms 9. Real Estate Market Disruptors 10. Smart Voice-Activated Assistants.

What was considered fringe science a decade ago is now rapidly becoming a mainstream industry. Our understanding of aging has advanced quickly in the last 10 years, and the tools and innovations seem to come more quickly with each passing year. A variety of therapies that target different aging processes are in development, and some are at fairly advanced stages; if you are interested in their progress, check out the Rejuvenation Roadmap.

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