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Researchers have identified a subpopulation of mesenchymal stem cells (MSCs) that boost the healing of bone fractures and show an ability to differentiate into various cell types.

Their findings are published in the journal Bone Reports in a paper titled, “Bone marrow CD73+ mesenchymal stem cells display increased stemness in vitro and promote fracture healing in vivo,” and led by researchers from the University of Tsukuba, in collaboration with the University of Bonn, Germany.

“MSCs are multipotent and considered to be of great potential for regenerative medicine,” the researchers wrote. “We could show recently (Breitbach, Kimura, et al. 2018) that a subpopulation of MSCs, as well as sinusoidal endothelial cells (sECs) in the bone marrow (BM) of CD73-EGFP reporter mice, could be labeled in vivo. We took advantage of this model to explore the plasticity and osteogenic potential of CD73-EGFP+ MSCs in vitro and their role in the regenerative response upon bone lesion in vivo.”

Acclaimed Harvard professor and entrepreneur Dr. David Sinclair believes that we will see human life expectancy increase to at least 100 years within this century. A world in which humans live significantly longer will have a major impact on economies, policies, healthcare, education, ethics, and more. Sinclair joined Bridgewater Portfolio Strategist Atul Lele to discuss the science and societal, political, systemic and ethical implications of humans living significantly longer lives.

Recorded: Aug 30 2021

The Science of Slowing Aging and Increasing Life Expectancy.
0:00 – 19:20

What Increasing Life Expectancy Means for Individuals.
19:20 – 30:40

The Impact on Pension, Healthcare and Education Systems.
30:40 – 44:18

The Economic Benefits of Longer Life Expectancy.
44:18 – 51:24

Four futurists and longevity leaders: Liz Parrish, José Cordeiro, Aubrey de Gray and David Wood, took the stage to discuss whether science and technology is heading us to the end of human death.

The discussion took place on october 6 2021, during the celebration of the event South Summit Innovation is Business that took place in Madrid from october 5 to 07.

The discussion dealt around the question “Are We Reaching the End of Human Death?”

José Cordeiro served as the host of the conversation.

“Our study is the first to discover that stimulation of the FFAR2 sensing mechanism by these microbial metabolites (SCFAs) can be beneficial in protecting brain cells against toxic accumulation of the amyloid-beta (Aβ) protein associated with Alzheimer’s disease,” said principal investigator Hariom Yadav, PhD, professor of neurosurgery and brain repair at the USF Health Morsani College of Medicine, where he directs the USF Center for Microbiome Research.


Fenchol, a natural compound abundant in some plants including basil, can help protect the brain against Alzheimer’s disease pathology, a preclinical study led by University of South Florida Health (USF Health) researchers suggests.

The new study published Oct. 5 in the Frontiers in Aging Neuroscience, discovered a sensing mechanism associated with the gut microbiome that explains how fenchol reduces neurotoxicity in the Alzheimer’s brain.

I hope we get the hologram interfaces depicted too.


It’s becoming clear that aging is just as curable as other diseases such as the cold or a broken bone. Advancements in biotechnology now allow for targeted gene therapy and supplements to be invented that can both stop aging and even reverse the aging process through new Longevity Technology. The field of Longevity has expanded and evolved a lot during the past few years and have invented new treatments for diseases of old people which could increase the average lifespan of people by a ton according to the leading scientists such as David Sinclair and Aubrey De Grey. Anti Aging Supplements such as Metformin and NAD+, NMN are just the start.

Every day is a day closer to the Technological Singularity. Experience Robots learning to walk & think, humans flying to Mars and us finally merging with technology itself. And as all of that happens, we at AI News cover the absolute cutting edge best technology inventions of Humanity.

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TIMESTAMPS:
00:00 A new Benchmark in Longevity.
01:04 Living longer lives today.
03:13 How Genomics will extend our lifespans.
05:19 What are the societal concerns?
07:58 Last Words.

#longevity #immortality #treatment

Comprehensive health, social services and economic well-being for american indian and alaska native elders — larry curley, executive director, national indian council on aging.


Mr. Larry Curley is Executive Director of The National Indian Council on Aging (https://www.nicoa.org/), a 501©(3) nonprofit organization founded in 1976 by members of the National Tribal Chairmen’s Association who called for a national organization focused on the needs of aging American Indian and Alaska Native elders. The mission of NICOA is to advocate for improved comprehensive health, social services and economic well-being for American Indian and Alaska Native elders.

Mr. Curley is a member of the Navajo Nation with over 40 years of experience working in the aging and healthcare fields. He has worked with Congress, other branches of the federal government, and national organizations on aging to develop support for programs affecting elder American Indians.

After receiving his master’s degree in public administration at the University of Arizona, along with a certificate in gerontology, Mr. Curley worked as a gerontological planner at an Area Agency on Aging in Pima County, Arizona, where he was instrumental in establishing a county public fiduciary program. As a lobbyist in Washington, D.C., he successfully advocated for the passage of Title VI of the Older Americans Act, an amendment which he wrote.

Mr. Curley directed the Navajo Nation’s Head Start program, one of the five largest Head Start programs in the country, and has served as a nursing home administrator of a tribal, long-term care facility, a hospital administrator in northern Nevada, and as a college instructor at the University of Nevada-Reno and Eastern Washington University.

Mr. Curley was named as the assistant dean of the Four Corners region for the Burrell College of Osteopathic Medicine. He’s also served as the public representative on the American College of Physicians Clinical Guidelines Committee, and as the director of program development for the Rehoboth McKinley Christian Health Care Services in northwest New Mexico.

Scientists in Montreal discover a new enzymatic complex that can stop cells from aging, opening the way to possible new cancer therapies.

Researchers at Université de Montréal and McGill University have discovered a new multi-enzyme complex that reprograms metabolism and overcomes “cellular senescence,” when aging cells stop dividing.

In their study published on September 16 2021, in Molecular Cell, the researchers show that an enzyme complex named HTC (hydride transfer complex) can inhibit cells from aging.

“The Foundation has created a unique and transparent mechanism for boosting early longevity research worldwide and ensuring mass public participation in decision making,” said Alex Zhavoronkov, Visionary Board member and an expert in AI-powered drug discovery. “This approach finally allows us to speak about getting closer to the idea of mass adoption of longevity ideas and treatments.”

“Age is the greatest risk factor for nearly every major cause of death and disability in developed nations. Therapeutically targeting biological aging is key to fulfilling the promise of 21st century medicine, and the Foundation is poised to play a central role in making this a reality,” said Matt Kaeberlein, CEO of the American Aging Association and Professor at the University of Washington, where he leads several major initiatives.

“In five years, healthy longevity will not only exist as a lab-proven concept, but will become part of everyone’s life,” said Andrea Maier, Visionary Board member and co-director of the Centre for Healthy Longevity at the National University of Singapore.