Lifeboat Foundation: Safeguarding Humanity
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Category: health

ProfusaLast week at CES, South San Francisco based Profusa showed off an upcoming injectable sensor that can be used to continuously monitor oxygen levels in tissue. Measuring only five millimeters long and a tiny 250 microns in diameter, the biosensor can be injected into tissue with just a hypodermic needle. It consists of a soft hydrogel scaffold that allows it to be biologically compatible with the surrounding tissue without any foreign body response. The sensor also contains a special chemical marker that changes fluorescence depending on the amount of oxygen that reacts with it. An optical reader placed on the skin measures the fluorescence and relays the data to a smartphone. The biosensor can last as long as two years (at which point the chemical marker begins to lose its potency), and because it contains no electronics and is completely biocompatible there’s no need to remove it.

On stage at the CES Digital Health Summit, Profusa CEO Dr. Ben Hwang gave a live demonstration of how the sensor works in action. As two of his colleagues with the sensors implanted and using a blood pressure cuffs performed stretches to simulate changes in blood flow, a graph displayed the live view of the changing tissue oxygen levels at the site of the sensors.

We had the opportunity to talk to Dr. Hwang after his talk, and he shared that the first application of the sensor is the Lumee Oxygen Sensing System, which is designed to monitor oxygen levels during the wound healing process. Sufficient oxygen flow through a wound is vital to the healing process, and Lumee can detect low oxygen levels early in the healing process and even before treatment or surgery begins.

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As we explore opportunities in space to colonized or even expand business opportunities in space such as mining, and discovering materials that could be brought back to earth to use; it will be important for scientists and researchers to look at ways in how technologies like CRISPR, nanobots, synthetic implants, etc. can assist in mitigating the impacts on humans in space.

A new report commissioned by NASA highlights many of the risks connected with one of the agency’s major goals: putting more humans in space for longer periods of time.

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The MMTP is testing Senolytics in an ambitious large scale mouse longevity project.

The goal of regenerative medicine is both quantity and quality whilst traditional medicine has provided quantity often at the cost of quality. Regenerative medicine proposes to reduce the frailty and decline of old age by rejuvenating the body and promoting healthy longevity. With advances in technology, research and our understanding of the aging process, this is now becoming a realistic proposition.

Some drugs already tested have been found to increase mouse lifespan such as Metformin 1,2 and Rapamycin 3.These drugs are even now moving into human clinical trials to see if the above benefits translate into people. However, there are many more promising substances that have never been properly tested and we do not know if they could extend healthy lifespan.

How fast science advances depends on how much quality research is being conducted. Currently there are few high impact studies investigating lifespan initiated each year ­ and with so many promising substances to test this is all a painfully slow process. The Major Mouse Testing Project [MMTP] is aiming to help by rapidly testing compounds and speeding up progress.

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Yelling at stem cells.

Acoustics experts have created a new class of sound wave — the first in more than half a century — in a breakthrough they hope could lead to a revolution in stem cell therapy.

The team at RMIT University in Melbourne, Australia, combined two different types of acoustic sound waves called bulk waves and surface waves to create a new hybrid: “surface reflected bulk waves”.

The first new class of sound wave discovered in decades, the powerful waves are gentle enough to use in biomedical devices to manipulate highly fragile stem cells without causing damage or affecting their integrity, opening new possibilities in stem cell treatment.

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A new survey has discovered a fear of frailty likely prevents widespread support of longevity, but if health is combined with years then it could well be a popular option.

Healthy longevity may convince people

According to the new survey, out of 1500 people 74.4% wished to live to 120 or longer if health was guaranteed, but only 57.4% wished to live that long if it wasn’t.

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The Osterhout Design Group, which has been making high-end night-vision goggles for years, has begun shipping its R-7 augmented reality glasses for enterprise applications. The $2,750 smartglasses are a sign of things to come, as the company eventually hopes to bring the technology to the masses at consumer prices.

Augmented reality is expected to become a $150 billion market by 2020, according to tech advisor Digi-Capital. But first, it has to become cheaper, lighter, and otherwise more practical. The R-7 represents ODG’s best trade-off between capability and cost. The company is showing the R-7 at the 2016 International CES, the big tech trade show in Las Vegas this week.

The ODG R-7 shows heads-up display images on the inside of the lenses, so you can see stereoscopic 3D or other animated imagery on top of objects in the real world. The company is targeting applications in health care, energy, transportation, warehouse, logistics, and government.

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The Wi-Fi Alliance branded its next-generation 802.11ah wireless protocol as Wi-Fi HaLow. It is targeted at the Internet of Things (IoT), which includes the smart home, connected car, and digital healthcare, as well as industrial, retail, agriculture, and smart-city environments. Unlike the older and more familiar 802.11 protocols, which mostly use the 2.4 or 5GHz bands, 802.11ah is a sub-gigahertz protocol that uses the 900MHz band. It has an enviable combination of characteristics.

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We may be fed a tale of ever expanding life expectancy, but while average lifespans may be rising maximum years are unchanged. If we want to keep extending the clock we need more than antibiotics and nutrition.

The easy work is done

While improving living standards and reducing infant mortality was not an easy job in itself, it extended years without fundamentally changing human biology. The incredible changes brought by the 20th century yielded longevity — but predominantly did so by lifting the majority closer to those luckier few. Even in the ancient world individuals seemingly lived over 80 years old; it was simply a rarer event to do so. You were significantly more likely to be felled by a disease beforehand, and many never reached such an advanced age as a result.

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It’s a new resin.

Researchers at Panasonic PCRFY −0.78% in Japan have developed a new kind of resin that has the potential to make personal health electronics leaner and comfier.

The stretchy tech, announced by the company on Dec. 28, can be used as a base for electronic materials. Its physical properties makes electronics easier to apply to skin or clothing—like a Band-Aid or a tattoo, rather than a watch or a strap.

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Are you a current or aspiring researcher working in the #aging field? Then you may be interested in the 23rd annual RAND Summer Institute in Santa Monica. This July, institute participants will attend a series of master lectures that offer insights into the science of aging, and the relationships between the aging field and health, economic status, and public policy. Register by March 15.

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