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Ultrasound imaging techniques have proved to be highly valuable tools for diagnosing a variety of health conditions, including peripheral artery disease (PAD). PAD, one of the most common diseases among the elderly, entails the blocking or narrowing of peripheral blood vessels, which limits the supply of blood to specific areas of the body.

Ultrasound imaging methods are among the most popular means of diagnosing PAD, due to their many advantageous characteristics. In fact, unlike other imaging methods, such as computed tomography angiography and , ultrasound imaging is non-invasive, low-cost and radiation-free.

Most existing ultrasound imaging techniques are designed to capture in real time. While this can be helpful in some cases, their inability to collect three-dimensional information reduces the reliability of the data they gather, increasing their sensitivity to variations in how individual physicians used a given technique.

Almost a third of working Americans are in some form of medical debt, with nearly a quarter of those with an outstanding balance owing $10,000 or more. Many Americans feel anxious about health care costs and are depleting their own savings to pay the bills, or avoiding going to the doctor due to the cost, and in some cases, as in the case of William Osman, embarking on bizarre projects to highlight the issue.

The YouTuber and engineer, who is known for his bizarre projects that combine engineering and entertainment, posted a video last week outlining how a recent hospital visit requiring X-rays resulted in a staggering $69,210.32 bill.

He explains that, thanks to his health insurance policy, he will only have to pay roughly $2,500, and that, when combined with annual insurance costs, the total will be around $8,500. In a comedic sequence, he laments, “I’m a slave to medical debt now. I have to sell all my things, I have to sell my friends’ belongings.” Then, he embarks on an extremely reckless and risky endeavor to build his own fully functional X-ray machine for less than the cost of his actual medical expenses.

“I think it’s changed everything, and I think it’s changed everything fundamentally,” James Livingston, a history professor at Rutgers University and the author of No More Work: Why Full Employment Is a Bad Idea, told Vox.

We’ll (probably) always have work, but could the job as the centerpiece of American life be on the way out?

To understand the question, you have to know how the country got to where it is today. The story starts, to some degree, with a failure. Much of American labor law — as well as the social safety net, such as it is — stems from union organizing and progressive action at the federal level in the 1930s, culminating in the New Deal. At that time, many unions were pushing for a national system of pensions not dependent on jobs, as well as national health care, Nelson Lichtenstein, a history professor at the University of California Santa Barbara, told Vox. They did win Social Security, but with many people left out, such as agricultural and domestic workers, it wasn’t a full nationwide retirement system. And when it came to universal health care, they lost entirely.

Drug delivery technologies have enabled the development of many pharmaceutical products that improve patient health by enhancing the delivery of a therapeutic to its target site, minimizing off-target accumulation and facilitating patient compliance. As therapeutic modalities expanded beyond small molecules to include nucleic acids, peptides, proteins and antibodies, drug delivery technologies were adapted to address the challenges that emerged. In this Review Article, we discuss seminal approaches that led to the development of successful therapeutic products involving small molecules and macromolecules, identify three drug delivery paradigms that form the basis of contemporary drug delivery and discuss how they have aided the initial clinical successes of each class of therapeutic. We also outline how the paradigms will contribute to the delivery of live-cell therapies.


This Review Article discusses how delivery challenges associated with small molecules, nucleic acids, peptides, proteins and cells led to the development of commercial products and are now informing the delivery of live-cell therapeutics.

Summary: Retrofitting wireless earbuds to detect neural signals and relaying the data back to smartphones via Bluetooth, researchers say the new earEEG system could have multiple applications, including health monitoring.

Source: UC Berkeley.

From keypads to touch screens to voice commands – step by step, the interface between users and their smartphones has become more personalized, more seamless. Now the ultimate personalized interface is approaching: issuing smartphone commands with your brain waves.

What do you do at different times in the day? What do you eat? How do you interact with your neighbors? These are some of the questions that biologists would love to ask communities of microbes, from those that live in extreme environments deep in the ocean to those that cause chronic infections in humans. Now, a new technique developed at Caltech can answer these questions by surveying gene expression across a population of millions of bacterial cells while still preserving the cells’ positions relative to one another.

The technique can be used to understand the wide variety of microbial communities on our planet, including the microbes that live within our gut and influence our health as well as those that colonize the roots of plants and contribute to soil health, to name a few.

The technique was developed at Caltech by Daniel Dar, a former postdoctoral scholar in the laboratory of Dianne Newman, Gordon M. Binder/Amgen Professor of Biology and Geobiology and executive officer for biology and biological engineering, and by Dr. Nina Dar, a former senior research technician in the laboratory of Long Cai, professor of biology and biological engineering. Daniel Dar is now an assistant professor at the Weizmann Institute of Science in Israel. A paper describing the research appears on August 12 in the journal Science.

The effects of fracking on nearby water sources may be worse than previously thought, according to a new study that found hydraulic fracturing can alter the composition of surface water and not just groundwater.

The study, published Thursday in Science, is the first to link fracking to small increases in salt concentrations in surface water, particularly during the early stages of production. While the highest salt levels were well below what the Environmental Protection Agency (EPA) considers harmful, researchers identified a robust association between new wells and water quality changes, triggering public health concerns.

“Our work provides the first large-scale sample evidence showing that hydraulic fracturing is related to the quality of nearby surface waters for several U.S. shales,” Christian Leuz, co-author of the study and a professor at the University of Chicago’s Booth School of Business, said in a news release.

Why are products sold that have not been fully tested for safety and public health?


A study led by researchers at the University of Toronto highlights the extensive damage that can be caused by common teeth-whitening agents.

Published recently in Nature Scientific Reports, the study assessed the dental cell damage caused by the use of carbamide peroxide teeth-whitening treatments.

It found that a recommended application of just 10 percent carbamide peroxide gel on teeth (35 percent carbamide peroxide gel can be purchased online) reduces the enamel protein content by up to 50 percent.

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Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
https://pubmed.ncbi.nlm.nih.gov/34369182/

Vitamin K2 amounts in food:
Menaquinones, Bacteria, and Foods: Vitamin K2 in the Diet.
https://www.intechopen.com/chapters/50921

Multiple Vitamin K Forms Exist in Dairy Foods.
https://pubmed.ncbi.nlm.nih.gov/29955705/

Menaquinone Content of Cheese.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946231/

Determination of Phylloquinone and Menaquinones in Food Effect of Food Matrix on Circulating Vitamin K Concentrations.
https://pubmed.ncbi.nlm.nih.gov/11356998/

SPACE STATION CREW MEMBER DISCUSSES LIFE IN SPACE WITH MEN’S HEALTH MAGAZINE

Aboard the International Space Station, Expedition 65 Flight Engineer Shane Kimbrough of NASA discussed life and research aboard the space station during an in-flight interview August 18 with Men’s Health Magazine. Kimbrough launched in April on a SpaceX Crew Dragon as part of a planned six-month mission.