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Category: genetics

New one from Liz.

Full Video ► https://goo.gl/tHvTF5
BioViva ► http://bioviva-science.com

Liz Parrish is the Founder and CEO of BioViva Sciences USA Inc. BioViva is committed to extending healthy lifespans using gene therapy. Liz is known as “the woman who wants to genetically engineer you,” she is a humanitarian, entrepreneur and innovator and a leading voice for genetic cures. As a strong proponent of progress and education for the advancement of gene therapy, she serves as a motivational speaker to the public at large for the life sciences. She is actively involved in international educational media outreach and sits on the board of the International Longevity Alliance (ILA). She is the founder of BioTrove Investments LLC and the BioTrove Podcasts which is committed to offering a meaningful way for people to learn about and fund research in regenerative medicine. She is also the Secretary of the American Longevity Alliance (ALA) a 501©(3) nonprofit trade association that brings together individuals, companies, and organizations who work in advancing the emerging field of cellular & regenerative medicine with the aim to get governments to consider aging a disease.

Parrish received two kinds of injections, which were administered outside the United States: a myostatin inhibitor, which is expected to prevent age-associated muscle loss; and a telomerase gene therapy, which is expected to lengthen telomeres, segments of DNA at the ends of chromosomes whose shortening is associated with aging and degenerative disease.

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Technically, an animal could use RNA editing to change the nature of its proteins without completely altering the underlying DNA instructions. This makes the cephalopods’ ability to do it a very interesting phenomenon, but it’s unclear as to why the species requires this much RNA editing. Many of the edited proteins were found in the animals’ brains, which is why scientists think the editing and their brainpower could be linked.

More than any other species on earth, octopuses are particularly smart—they can solve puzzles, use tools, and communicate using color. Now scientists are saying they’re also capable of editing their RNA.

A team of scientists led by Joshua Rosenthal at the Marine Biological Laboratory and Noa Liscovitch-Braur and Eli Eisenberg at Tel Aviv University have discovered that octopuses and squid are capable of a type of genetic alteration called RNA editing. The process is rare among other species, leading scientists to believe that the cephalopods have evolved to follow a special kind of gene recoding.

Normally, living creatures use the information contained in DNA to make proteins, and RNA is the go-between, simply transmitting the message in the DNA. More than 60 percent of RNA transcripts in squid are recoded by editing, and similar levels of RNA editing were identified in other cephalopod species, including two octopuses and a cuttlefish. This changes the message that gets sent out, which in turn changes the proteins that get produced. In comparison, other species like fruit flies and humans experience recoding events only a fraction of one percent of the time. But exactly how the gene editing mechanics work is a mystery.

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Carriers of the mutation are essentially playing catch-up for their entire lives.

Any night owls reading this will be familiar with the struggle of constantly trying to fit into a morning person’s world. And now researchers say they’ve finally identified the genetic typo that causes this social jetlag.

A new study has revealed that many people who stay up late and struggle to wake up in the morning aren’t lazy, their internal clock is simply genetically programmed to run between 2 and 2.5 hours slower than the rest of the population, thanks to a mutation in a body clock gene called CRY1.

“Carriers of the mutation have longer days than the planet gives them, so they are essentially playing catch-up for their entire lives,” says lead researcher Alina Patke from The Rockefeller University in New York.

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China has made the precision medicine field a focus of its 13th five-year plan, and its companies have been embarking on ambitious efforts to collect a vast trove of genetic and health data, researching how to identify cancer markers in blood, and launching consumer technologies that aim to tap potentially life-saving information. The push offers insight into China’s growing ambitions in science and biotechnology, areas where it has traditionally lagged developed nations like the United States.

Precision medicine a focus of latest five-year plan.

PUBLISHED : Thursday, 09 February, 2017, 1:42pm.

UPDATED : Thursday, 09 February, 2017, 1:42pm.

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Transhumanism stuff out in these stories: http://z-news.link/the-future-of-the-earth-through-the-eyes-of-futurists-photo/ & http://yemcentral.com/2017/03/29/would-robots-make-better-politicians-than-humans/ & https://player.fm/series/lions-of-liberty-podcast/287-zoltan-istvan-on-the-transhumanist-movement-and-liberty

Futurism, or more precisely, futurology, is the study of possible hypotheses, probable and preferred options for the future. To understand what futurists predict in the improvement of the human condition, consider the progress happening in the field of science, medicine and computing.

1. Cure Alzheimer’s disease

Будущее Земли глазами футурологов. Фото

Alzheimer’s disease is type of dementia that causes problems with memory, thinking abilities and behavior. It is a progressive disease, which means that the disease gets worse over time. Only in the US estimated to suffer her 5.4 million people. Today for Alzheimer’s disease there is no cure, but one group of scientists believes that it will be able to figure out a way to deal with it.

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  • In 2016 alone, 58,320 people in the U.S. died from leukemia. This new development could increase a patients’ chance of survival
  • Current treatment methods can increase a patient’s risk of secondary cancer after remission. This Engineered T-Cell approach has not shown to be carcinogenic

Wouldn’t it be wonderful if the need for chemotherapy no longer existed? In some cases, these treatments aren’t even effective enough to send patients into remission, but for many people, there are few other options.

What if there was an easier and more effective way to tackle cancer? Thanks to one recent case, there is.

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The race is on to edit genes and prevent disease. But this technology is ripe for abuse.

Economic inequity already exists in the reproductive industry. IVF, for example, is not covered by insurance in most states (Massachusetts excepted), setting up a situation in which only infertile people with well-padded pockets can afford the treatment. And of course the well-off have easier access to good health care via quality private insurance — or their own bank accounts. Steve Jobs, for example, spent $100,000 in 2011 to sequence his genome and that of his pancreatic tumor — a bill not many could hope to afford.

“The beautiful thing about this [gene-editing] work is it offers an opportunity to intervene around the moment of birth,” says Katy Kozhimannil, an associate professor in the Division of Health Policy at University of Minnesota’s School of Public Health. “That said, as we pay attention to the opportunity of that moment, it’s important to bear in mind the value of liberty and justice for all.”

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Genomic instability (mutations) has been suggested as being one of the primary hallmarks of aging and this research might support that idea. Researchers at John Hopkins report that around 66% of mutations in cancer cells are due to random errors with environment/lifestyle contributing 29% and 5% inherited.

“That finding challenges the common wisdom that cancer is the product of heredity and the environment. “There’s a third cause and this cause of mutations is a major cause,” says cancer geneticist Bert Vogelstein.”

“Such random mutations build up over time and help explain why cancer strikes older people more often. Knowing that the enemy will strike from within even when people protect themselves against external threats indicates that early cancer detection and treatment deserve greater attention than they have previously gotten, Vogelstein says.”

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RUPTURE follows Renee Morgan (Noomi Rapace), a single mom, who is deathly terrified of spiders. While in route to meet up with a friend, she is violently abducted by a group of strangers. After enduring intense yet strange questioning and examinations, some about her fear of spiders, Renee soon discovers that she is now the subject of an underground experiment. Her captors explain to her that she has a genetic abnormality that can potentially allow her to “rupture” and reveal her alien nature. Renee must find a way to escape before it is too late.

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