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One way that scientists can non-invasively study the human brain is by growing “mini-brains,” clusters of brain cells each about the size of a pea, in the lab. In a fascinating progression of this line of research, a team this week reports that they observed human-like brainwaves from these organoids.

Previous studies of mini-brains have demonstrated movement and nerve tract development, but the new study from researchers at the University of California San Diego, led by biologist Alysson Muotri, is the first to record human-like neural activity. In their paper, published in Cell Stem Cell on Thursday, the researchers write that they observed brain wave patterns resembling those of a developing human. This sophistication in the in vitro model is a step to enable scientists to use mini-brains to study brain development, model diseases, and learn about the evolution of brains, according to Muotri.

Dubbed ‘antibiotic apocalypse’, the antibiotic resistant superbugs have become a massive cause for concern for health professionals as their numbers continue to rise. Such is the worry around antibiotic superbugs that experts believe that they will claim 10 million lives by 2050, with 700,000 people dying a year after catching the infections, according to a recent report from the American Chemical Society’s Enviromental Science and Technology Journal. Humans, especially in the West, have become so reliant on antibiotics to help cure illnesses that many of the bacteria that they are trying to fight have become resistant to the drugs through evolution.

Physics World represents a key part of IOP Publishing’s mission to communicate world-class research and innovation to the widest possible audience. The website forms part of the Physics World portfolio, a collection of online, digital and print information services for the global scientific community.

When energy is added to uranium under pressure, it creates a shock wave, and even a tiny sample will be vaporized like a small explosion. By using smaller, controlled explosions, physicists can test on a microscale in a safe laboratory environment what could previously be tested only in larger, more dangerous experiments with bombs.

“In our case, it’s the laser depositing energy into a target, but you get the same formation and time-dependent evolution of plasma,” author Patrick Skrodzki said. “With these small-scale explosions in the lab, we can understand similar physics.”

In a recent experiment, scientists working with Skrodzki used a laser to ablate atomic uranium, stealing its electrons until it ionized and turned to plasma, all while recording as the plasma cooled, oxidized and formed species of more complex uranium. Their work puts uranium species and the reaction pathways between them onto a map of space and time to discover how many nanoseconds they take to form and at which part of the plasma’s evolution.

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When it comes to age reversal and complex regeneration in humans, a basin of research has been put in front of us. How much do we know about the brain, consciousness, and death reversal? As Big Pharma makes a trillion dollars annually, are they interested in finding cures? What valuable lessons are we learning from evolution?

On this episode, we have an in-depth conversation about exciting developments in biology with Bioquark CEO, Ira Pastor.

We’re only a handful of months away from the year 2020, and with the way parts look and tech acts, it finally feels like we’re entering the future. It’s a future crafted by sophisticated 3D printers and machining centers, using materials provided by global-reaching supply chains and connected to an exponential rate of new superpowered gadgets. Nowadays, there’s really no reason to think any manufacturing feat is impossible. If something doesn’t exist, it’s just that we haven’t figured it out yet.

And this futuristic techtopia brimming with potential wouldn’t be possible if not for engineers—those dedicated, uber-creative folks plotting such a course, continuously improving the world around through the super power of… math.

Mathematics has been the indispensable fuel to make the impossible possible since at least the ancient Egyptians more than four thousand years ago. The Great Pyramid of Giza is the world’s oldest monument to its power. Amazingly, its geometrical elegance was calculated on papyrus scrolls, most of which have turned to dust long ago. Yet the universal language of math still speaks through its dimensions. And it will continue to do so for time immemorial.

The EOR will also provide an unprecedented test for the current best model of cosmic evolution. Although there is plenty of evidence for dark matter, nobody has identified exactly what it is. Signals from the EOR would help to indicate whether dark matter consists of relatively sluggish, or ‘cold’, particles — the model that is currently favoured — or ‘warm’ ones that are lighter and faster, says Anna Bonaldi, an astrophysicist at the Square Kilometre Array (SKA) Organisation near Manchester, UK. “The exact nature of dark matter is one of the things at stake,” she says.


Radioastronomers look to hydrogen for insights into the Universe’s first billion years.

What is reality and how do we know? For many the answer is simple: What you see — hear, feel, touch, and taste — is what you get.

Your skin feels warm on a summer day because the sun exists. That apple you just tasted sweet and that left juices on your fingers, it must have existed. Our senses tell us that reality is there, and we use reason to fill in the blanks — that is, we know the sun doesn’t cease to exist at night even if we can’t see it.

But cognitive psychologist Donald Hoffman says we’re misunderstanding our relationship with objective reality. In fact, he argues that evolution has cloaked us in a perceptional virtual reality. For our own good.

Aubrey de Grey, Ph.D., Vice President of New Technology Discovery for AgeX Therapeutics, discusses how primitive organisms have better regenerative capacity than more complicated organisms such as humans. In humans, Dr. de Grey notes, our best regenerative abilities are at the embryonic stage. During the Embryonic Fetal Transition, out ability to regenerate plummets and continues to diminish as we age. Dr. de Grey discusses the role evolution plays in this and how scientists may be able to “revive” our regenerative power. This video is part of a series from AgeX on research into aging and human longevity. For more information on Agex Therapeutics, please visit http://www.agexinc.com.