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Category: evolution

New interview with author and researcher Dr. Josh Mitteldorf who runs the aging research blog Aging Matters.

Interview with author and researcher Dr. Josh Mitteldorf who runs the aging research blog ‘Aging Matters’.

Dr. Josh Mitteldorf is an evolutionary biologist and a long-time contributor to the growing field of aging science. His work in this field has focused on theories of aging. He asks the basic question: why do we age and die?

Josh is the co-author of ‘Cracking the Aging Code: The New Science of Growing Old — And What It Means for Staying Young’ : “A revolutionary examination of why we age, what it means for our health, and how we just might be able to fight it.

In Cracking the Aging Code, theoretical biologist Josh Mitteldorf and award-winning writer and ecological philosopher Dorion Sagan reveal that evolution and aging are even more complex and breathtaking than we originally thought. Using meticulous multidisciplinary science, as well as reviewing the history of our understanding about evolution, this book makes the case that aging is not something that “just happens,” nor is it the result of wear and tear or a genetic inevitability. Rather, aging has a fascinating evolutionary purpose: to stabilize populations and ecosystems, which are ever-threatened by cyclic swings that can lead to extinction.

When a population grows too fast it can put itself at risk of a wholesale wipeout. Aging has evolved to help us adjust our growth in a sustainable fashion as well as prevent an ecological crisis from starvation, predation, pollution, or infection.

This dynamic new understanding of aging is provocative, entertaining, and pioneering, and will challenge the way we understand aging, death, and just what makes us human.“

Many thanks for watching!

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Cooperation means that one individual pays a cost for another to receive a benefit. Cooperation can be at variance with natural selection: Why should you help a competitor? Yet cooperation is abundant in nature and is an important component of evolutionary innovation. Cooperation can be seen as the master architect of evolution and as the third fundamental principle of evolution beside mutation and selection. I will present mathematical principles of cooperation.

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An experiment nearly two decades in the making has finally unveiled its measurements of the mass of the universe’s most abundant matter particle: the neutrino.

The neutrino could be the weirdest subatomic particle; though abundant, it requires some of the most sensitive detectors to observe. Scientists have been working for decades to figure out whether neutrinos have mass and if so, what that mass is. The Karlsruhe Tritium Neutrino (KATRIN) experiment in Germany has now revealed its first result constraining the maximum limit of that mass. The work has implications for our understanding of the entire cosmos, since these particles formed shortly after the Big Bang and helped shape the way structure formed in the early universe.

“You don’t get a lot of chances to measure a cosmological parameter that shaped the evolution of the universe in the laboratory,” Diana Parno, an assistant research professor at Carnegie Mellon University who works on the experiment, told Gizmodo.

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Guppies, a perennial pet store favorite, have helped a UC Riverside scientist unlock a key question about evolution:

Do animals evolve in response to the risk of being eaten, or to the environment that they create in the absence of predators? Turns out, it’s the latter.

David Reznick, a professor of biology at UC Riverside, explained that in the wild, guppies can migrate over waterfalls and rapids to places where most predators can’t follow them. Once they arrive in safer terrain, Reznick’s previous research shows they evolve rapidly, becoming genetically distinct from their ancestors.

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Near an old mining town in Central Europe, known for its picturesque turquoise-blue quarry water, lay Rudapithecus. For 10 million years, the fossilized ape waited in Rudabánya, Hungary, to add its story to the origins of how humans evolved.

What Rudabánya yielded was a pelvis—among the most informative bones of a skeleton, but one that is rarely preserved. An international research team led by Carol Ward at the University of Missouri analyzed this new pelvis and discovered that bipedalism—or the ability for people to move on two legs—might possibly have deeper ancestral origins than previously thought.

The Rudapithecus pelvis was discovered by David Begun, a professor of anthropology at the University of Toronto who invited Ward to collaborate with him to study this fossil. Begun’s work on limb bones, jaws and teeth has shown that Rudapithecus was a relative of modern African apes and humans, a surprise given its location in Europe. But information on its posture and locomotion has been limited, so the discovery of a pelvis is important.

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A dietary supplement, sarcosine, may help with schizophrenia as part of a holistic approach complementing antipsychotic medication, according to a UCL researcher.

In an editorial published in the British Journal of Psychiatry, Professor David Curtis (UCL Genetics, Evolution & Environment and QMUL Centre for Psychiatry) suggests the readily available product could easily be incorporated into treatment plans, while calling for clinical trials to clarify the benefit and inform guidelines.

“Sarcosine represents a very logical treatment and the small number of so far do seem to show that it can be helpful. It certainly seems to be safe and some patients report feeling better on it,” he said.

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In the version of evolutionary theory most of us are familiar with, randomly occurring variation in traits, caused by mutations in our DNA, can be fixed in a population through natural selection. However, writing in Epigenetics journal, a team of Swedish researchers from Linköping University suggests that mutations that can be caused by environmental changes, not just random chance, might be responsible for species diversity.

Until quite recently, it was assumed that DNA causing new gene variations occurred more or less randomly. While random mutations do occur, recent research has shown that can be altered by environmental influences too. According to a study published in Epigenetics journal, a particular type of mutation, linked to , has, over time, led to new animal breeds—and could be responsible for whole new species.

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The recent discovery of a 3.8m-year-old cranium (skull without the lower jaw) is the hottest topic of conversation among palaeoanthropologists right now. But fossils are found all the time, so why is the cranium of this small, old man so important? It turns out the discovery is changing our view of how early hominin species evolved – and how they led to humans. To understand how, let’s start at the beginning.

In 1995, researchers found several partial jaws, isolated teeth and limb bones in Kenya, dated between 4.2m and 3.9m years old, and assigned them to a brand new species: Australopithecus anamensis. All these fossils were found in sediments associated with an ancient lake – “anam”, which means lake in the local language. A number of additional specimens were then found in Ethiopia, thought to belong to the same species.

The primitive features of A. anamensis have led to the widespread view that this species is the ancestor of Australopithecus afarensis, a younger hominin from Tanzania, Ethiopia and perhaps Kenya, dated between 3.8m and 3m years old. The most iconic fossil of A. afarensis is probably the partial skeleton known as Lucy, which was for a long time viewed as the oldest known human ancestor.

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Providing a glimpse the hidden workings of evolution, a group of researchers at UC Santa Barbara have discovered that embryos that appear the same can start out with surprisingly different instructions.

“We found that a lot of undercover evolution occurs in ,” said Joel Rothman, a professor in the Department of Molecular, Cellular, and Developmental Biology, who led the team.

Indeed, although members of the same species are identical across the vast majority of their genomes, including all the genetic instructions used in development, Rothman and his colleagues found that key parts of the assembly instructions used when embryos first start developing can differ dramatically between individuals of the same species.

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A handful of spins in diamond have shone new light on one of the most enduring mysteries in physics – how the objective reality of classical physics emerges from the murky, probabilistic quantum world. Physicists in Germany and the US have used nitrogen-vacancy (NV) centres in diamond to demonstrate “quantum Darwinism”, whereby the “fittest” states of a system survive and proliferate in the transition between the quantum and classical worlds.

In the past, physicists tended to view the classical and quantum worlds as being divided by an abrupt barrier that makes a fundamental distinction between the familiar macroscopic (classical) and the unfamiliar microscopic (quantum) realms. But in recent decades that view has changed. Many experts now think that the transition is gradual, and that the definite classical states we measure come from probabilistic quantum states progressively (although very quickly) losing their coherence as they become ever more entangled with their environment.

Quantum Darwinism, put forward by Wojciech Zurek of Los Alamos National Laboratory in New Mexico, argues that the classical states we perceive are robust quantum states that can survive entanglement during decoherence. His theoretical framework posits that the information about these states will be duplicated many times and disseminated throughout the environment. Just as natural selection tells us that the fittest individuals in a species must survive to reproduce in great numbers and so go on to shape evolution, the fittest quantum states will be copied and appear classical. This redundancy means that many individual observers will measure any given state as having the same value, so ensuring objective reality.

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