𝙏𝙝𝙚 𝙙𝙞𝙨𝙘𝙤𝙫𝙚𝙧𝙮 𝙖𝙙𝙫𝙖𝙣𝙘𝙚𝙨 𝙪𝙣𝙙𝙚𝙧𝙨𝙩𝙖𝙣𝙙𝙞𝙣𝙜 𝙤𝙛 𝙩𝙝𝙚 𝙧𝙤𝙡𝙚 𝙤𝙛 𝙜𝙪𝙩-𝙗𝙧𝙖𝙞𝙣 𝙘𝙤𝙢𝙢𝙪𝙣𝙞𝙘𝙖𝙩𝙞𝙤𝙣𝙨 𝙞… See more.
The discovery advances understanding of the role of gut-brain communications in the development of multiple sclerosis and homes in on a potential therapeutic target
NEW YORK, December 20, 2021 — A New York-based, multi-institutional research team has found high levels of three toxic metabolites produced by gut bacteria in the cerebrospinal fluid and plasma samples of multiple sclerosis (MS) patients. The important findings, published in the journal Brain, further scientists’ understanding of how gut bacteria can impact the course of neurological diseases by producing compounds that are toxic to nerve cells.
Previously published evidence has supported the concept that an imbalance in the gut microbiota—the community of organisms that live in the human intestines—may underly a range of neurological disorders. Researchers also found that certain gut bacteria are either enriched or depleted in MS patients compared to healthy individuals, but it is unclear how these microbes communicate with the brain and affect the neurodegenerative disease process.
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When we think about gene editing, the first thing we remember is the designer babies, and that it’s usually called unethical. But actually, gene editing (CRISPR) may be one of the most promising upcoming medical technologies. Learn why in this video.
Check out other videos from this series: https://www.youtube.com/playlist?list=PLnWSi4zEceYXPCBYXZ9ZEV-9q44ebksoo.
0:00 — Opening scene. 0:20 — Gene editing is promising. Here’s why. 2:35 — Also, it can transform the beauty industry. 3:49 — How does gene editing work? 4:16 — My thoughts on that. 5:16 — End credits.
Europe will soon produce a strategically vital component in the modern global economy as US semiconductor giant Intel chooses the site for a new cutting-edge chip factory.
Recent problems in global supply chains have highlighted the fundamental importance of semiconductors, which are used in a growing number of products including cars, TVs and smartphones.
Keen demand and the closure of semiconductor plants, particularly in Asia, due to pandemic disruptions led to a global chip shortage and forced car manufacturers such as Ford, Nissan and Volkswagen to scale back production.
All 18 COVID-19 patients hospitalized with moderate or severe symptoms who were administered the drug Amor-18 developed by Israeli biotech company Amorphical in a phase II clinical trial recovered and were discharged in a few days, the company announced Wednesday. Of the 19 individuals who were given a placebo, six had to be transferred to intensive care, and two died.
All 18 hospitalized individuals administered the treatment developed by Israeli biotech company Amorphical in a phase II trial recovered and were discharged in a few days.
Israel has announced a fourth dose of the COVID-19 vaccine to people older than 16. The additional dose will be given to senior citizens, medical workers, people with suppressed immune system.
#Israel #COVID #ImmuneSystem.
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Companies and labs are racing to build next-generation devices that track and translate brain activity to help people immobilized by disease or injury handle tasks requiring movement.
Artificial intelligence (AI) backed drug discovery company Insilico Medicine announced last week that it was dosing the first healthy volunteer in a microdose trial of ISM 001–005. Designed with the help of AI, the drug is a small-molecule inhibitor of a biological target that was discovered by Pharma. AI. The trial is being conducted in Australia.
The AI-designed drug will be used to treat chronic lung disease idiopathic pulmonary fibrosis, or IPF usually leads to progressive and irreversible lung-function decline and affects 20 people out of over 100,000 globally.
Chief Scientific Officer of Insilico, Freng Ren, said in a press release that this drug discovery and trial marks a significant milestone in the AI-drug discovery space. This is because the said candidate is the first-ever AI-discovered novel molecule based on an AI-discovered target.