Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: biotech/medical

That’s why researchers have developed high-tech glasses, called Amblyz, which can be programmed to treat lazy eye. The results of the first clinical trial assessing their efficacy were presented this week at the annual meeting of the American Academy of Ophthalmology.

Amblyz works because its lenses contain programmable LCDs. If a doctor suggested that a child wear a patch for two hours per day, for example, the lens over the lazy eye would go dark for a few seconds out of every 30 seconds during that time, effectively working as a patch. And since children with amblyopia often have other vision problems such as astigmatism or nearsightedness, Amblyz corrects their vision when not occluding it.

Read more

Where do we come from? There are many right answers to this question, and the one you get often depends on who you ask.

For example, an astrophysicist might say that the chemical components of our bodies were first forged in the nuclear fires of stars.

On the other hand, an evolutionary biologist might look at the similarities between our DNA and that of other primates’ and conclude we evolved from apes.

Read more

Memories are priceless, and the plight of dementia patients highlights how important they are to forming what makes us, well us. Now a new study has provided hope we may one day be able to restore lost memories.

Clearing the mist

A paper from researchers at MIT has demonstrated the reactivation of memories in amnesia patients with optogenetics — in which cell activity is controlled by bursts of light.

Read more

Opening up the blood-brain barrier to deliver drugs (credit: Focused Ultrasound Foundation)

The blood-brain barrier has been non-invasively opened in a human patient for the first time. A team at Sunnybrook Health Sciences Centre in Toronto used focused ultrasound to temporarily open the blood-brain barrier (BBB), allowing for effective delivery of chemotherapy into a patient’s malignant brain tumor.

The team infused the chemotherapy agent doxorubicin, along with tiny gas-filled bubbles, into the bloodstream of a patient with a brain tumor. They then applied focused ultrasound to areas in the tumor and surrounding brain, causing the bubbles to vibrate, loosening the tight junctions of the cells comprising the BBB, and allowing high concentrations of the chemotherapy to enter targeted tissues.

Read more

Resetting Your Biological Clock: New Enzyme Found To Repair Telomeres.

The telomere caps on the end of your chromosomes unravel bit by bit with every cell division, and if they’re not repaired division eventually stops altogether. Cells like stem cells express special enzymes to lengthen these caps, and we’ve now found another one that does the job.

A key player in aging?

Many factors drive aging, but telomeres play a key role in allowing cells to divide at all and are therefore a major potential anti-aging target. Aging is a murder mystery case involving a range of perpetrators, but telomere shortening has been connected to multiple age-related diseases and many scientists believe we’ll have to find ways to repair telomeres if we want to live longer.

Read more

I had read about Singapore in genetic engineering way back in the 90’s. I think they were 1st or 2nd in making immortal skin cells at the time.

Singapore scientists have unravelled a mystery that could pave the way for turning back the clock on ageing.

A recent study led by Dr Ng Shyh Chang of the Genome Institute of Singapore at the Agency for Science, Technology and Research (A*Star) has found a gene in human egg cells that suppresses an enzyme causing cells to age.

This is the Tcl1 gene, and by increasing the protein it produces, the researchers found they could suppress the enzyme that causes mitochondria — the cells’ batteries — to age over time.

Read more

This animation depicts the CRISPR-Cas9 method for genome editing – a powerful new technology with many applications in biomedical research, including the potential to treat human genetic disease. Feng Zhang, a leader in the development of this technology, is a faculty member at MIT, an investigator at the McGovern Institute for Brain Research, and a core member of the Broad Institute. Further information can be found on Prof. Zhang’s website at http://zlab.mit.edu.

Images and footage courtesy of Sputnik Animation, the Broad Institute of MIT and Harvard, Justin Knight and pond5.

Read more

Treating the brain often requires invasive surgery, but a new technique involving ultrasound and air bubbles has now shown promise at delivering drugs through the blood-brain barrier.

One of the biggest challenges of medicating brain tumours is actually getting drugs into the organ. Your brain is well protected from invasion by untoward substances or life forms, and this protection limits what will enter from the bloodstream. There have been previous efforts to open up the barrier, but they often involve a surgical approach that is far from ideal.

Read more

New article for Vice Motherboard on why society should support legalization of all drugs–and a short video of the Immortality Bus in Arkansas talking to marijuana supporters (a state where it’s totally illegal):

The “Mount Rushmore of the Drug War” featuring founding prohibitionists Harry Anslinger, Billie Holiday, and Arnold Rothstein. Image: Donkey Hotey/Flickr

I’m from San Francisco. Doing drugs—especially smoking pot—seems second nature to me. I’ve made a point of trying nearly all drugs, and I’m unabashedly proud of that fact. I consider Aldous Huxley’s The Doors of Perception one of the most important books I read in my youth, and I’ve often wondered if it should be mandatory that everyone try a hallucinogenic drug at least once in their lives.

Almost all transhumanists welcome and endorse mind-altering substances. We thrive off change, experimentation, and new experiences, including wild drug trips with friends. For transhumanists, trying drugs is not just about having fun, but about self-amelioration and becoming the best, most enlightened versions of ourselves.

I’m driving a bus across the country to deliver a Transhumanist Bill of Rights to the US Capitol. One of those rights will certainly include language that advocates for citizens being able to take any drugs they want, so long as the taking of it doesn’t directly hurt someone else.

Read more