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Category: biotech/medical

Researchers from 21st Century Medicine have developed a new technique to allow long term storage of a near-perfect mammalian brain. It’s a breakthrough that could have serious implications for cryonics, and the futuristic prospect of bringing the frozen dead back to life.

By using a chemical compound to turn a rabbit’s brain into a near glass-like state, and then cooling it to −211 degrees Fahrenheit (−135 degrees Celsius), a research team from California-based 21st Century Medicine (21CM) showed that it’s possible to enable near-perfect, long-term structural preservation of an intact mammalian brain. The achievement has earned not just accolades from the scientific community, but a prestigious award as well; the 21CM researchers are today being awarded the $26,735 Small Mammal Brain Preservation Prize, which is run by the Brain Preservation Foundation (BPF).

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The Brain Preservation Foundation (BPF) announced that the Small Mammal Brain Preservation Prize has officially been won. The spectacular result achieved by 21st Century Medicine researchers provides the first demonstration that near-perfect, long-term structural preservation of an intact mammalian brain is achievable.

A team from 21st Century Medicine, spearheaded by recent MIT graduate Robert McIntyre, has discovered a way to preserve the delicate neural circuits of an intact rabbit brain for very long-term storage using a combination of chemical fixation and cryogenic cooling. Proof of this accomplishment, and the full “Aldehyde-Stabilized Cryopreservation” (ASC) protocol, was recently published in the journal Cryobiology and has been independently verified by the BPF through extensive electron microscopic examination conducted by the two official judges of the prize: BPF President Ken Hayworth and Princeton neuroscience professor Sebastian Seung, author of “Connectome: How the Brain’s Wiring Makes Us Who We Are.”

“Every neuron and synapse looks beautifully preserved across the entire brain,” said Hayworth. “Simply amazing given that I held in my hand this very same brain when it was frozen solid… This is not your father’s cryonics.”

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NASA laser expert Mike Krainak and his team plan to replace portions of this fiber-optic receiver with an integrated-photonic circuit (its size will be similar to the chip he is holding) and will test the advanced modem on the International Space Station. (credit: W. Hrybyk/NASA)

A NASA team plans to build the first integrated-photonics modem, using an emerging, potentially revolutionary technology that could transform everything from telecommunications, medical imaging, advanced manufacturing to national defense.

The cell phone-sized device incorporates optics-based functions, such as lasers, switches, and fiber-optic wires, onto a microchip similar to an integrated circuit found in all electronics hardware.

The device will be tested aboard the International Space Station beginning in 2020 as part of NASA’s multi-year Laser Communications Relay Demonstration (LCRD). The Integrated LCRD LEO (Low-Earth Orbit) User Modem and Amplifier (ILLUMA) will serve as a low-Earth-orbit terminal for NASA’s LCRD, demonstrating another capability for high-speed, laser-based communications.

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Researchers at Sanford Burnham Prebys Medical Research Institute (SBP) have conclusively identified the protein complex that controls the genes needed to repair skeletal muscle. The discovery clears up deep-rooted conflicting data and will now help streamline efforts towards boosting stem cell-mediated muscle regeneration. Such strategies could treat muscle degenerative diseases such as muscular dystrophies, and those associated with aging and cancer.

The research, published today in eLife, describes the essential role of a TBP-containing TFIID-protein complex in activating genes that regenerate muscle tissue, and shows that an alternative protein called TBP2 is not involved in this task in adult muscles.

“Our discovery clarifies the identity of the ‘molecular switches’ that control the activation of muscle genes in (MuSCs),” said Barbora Malecova, Ph.D., postdoctoral fellow in the laboratory of Pier Lorenzo Puri, M.D., professor in the Development, Aging and Regeneration Program at SBP, and first author of the article. “Understanding what drives muscle gene expression gives us insights into molecular targets for regenerative medicine-based interventions (drugs) to treat muscle degenerative disorders.”

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The US military is looking for ways to insert microscopic devices into human brains to help folks communicate with machines, like prosthetic limbs, with their minds. And now, DARPA’s saying scientists have found a way to do just that—without ripping open patients’ skulls.

In the DARPA-funded study, researchers at the University of Melbourne have developed a device that could help people use their brains to control machines. These machines might include technology that helps patients control physical disabilities or neurological disorders. The results were published in the journal Nature Biotechnology.

In the study, the team inserted a paperclip-sized object into the motor cortexes of sheep. (That’s the part of the brain that oversees voluntary movement.) The device is a twist on traditional stents, those teeny tiny tubes that surgeons stick in vessels to improve blood flow.

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Another cancer therapy; healthcare seems to be on a roll.

An experimental nanoparticle therapy that combines low-density lipoproteins (LDL) and fish oil preferentially kills primary liver cancer cells without harming healthy cells, UT Southwestern Medical Center researchers report.

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Great story; I hope it helps many talented game developers realize what you mean to kids; and especially those children who fight cancer.

A lot of people are coming together right now to help a teenager who is fighting cancer in a local hospital. It’s not just his family or doctors and nurses either. Complete strangers are giving their all to help him accomplish his high-tech dream.

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