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Arthritis sufferers have been offered new hope after scientists grew a ‘living hip’ in the lab which not only replaces worn cartilage but stops painful joints returning.

Researchers in the US have used stem cells to grow cartilage in the exact shape of a hip joint while also genetically engineering the tissue to release anti-inflammatory molecules to fend off the return of arthritis.

The idea is to implant the perfectly shaped cartilage around the joint to extend its life before arthritis has caused too much damage to the bone.

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Researchers at the Stanford University School of Medicine found a way to trick human embryonic stem cells to become pure populations of any of 12 cell types, including bone, heart muscle and cartilage within days.

Scientists at the Stanford University School of Medicine have identified the sets of biological and chemical signals necessary to quickly and efficiently direct human embryonic stem cells. If successful, researchers could grow pure populations of any of 12 cell types, including bone, heart muscle and cartilage within days rather than the weeks or months previously required.

This is key toward clinically useful regenerative medicine – potentially allowing researchers to generate new beating heart cells to repair damage after a heart attack or to create cartilage or bone to reinvigorate creaky joints or heal from trauma.

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Biowire.


Researchers led by microbiologist Derek Lovely say the wires, which rival the thinnest wires known to man, are produced from renewable, inexpensive feedstocks and avoid the harsh chemical processes typically used to produce nanoelectronic materials.

Lovley says, “New sources of electronic materials are needed to meet the increasing demand for making smaller, more powerful electronic devices in a sustainable way.” The ability to mass-produce such thin conductive wires with this sustainable technology has many potential applications in electronic devices, functioning not only as wires, but also transistors and capacitors. Proposed applications include biocompatible sensors, computing devices, and as components of solar panels.

This advance began a decade ago, when Lovley and colleagues discovered that Geobacter, a common soil microorganism, could produce “microbial nanowires,” electrically conductive protein filaments that help the microbe grow on the iron minerals abundant in soil. These microbial nanowires were conductive enough to meet the bacterium’s needs, but their conductivity was well below the conductivities of organic wires that chemists could synthesize.

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In the campy 1966 science fiction movie “Fantastic Voyage,” scientists miniaturize a submarine with themselves inside and travel through the body of a colleague to break up a potentially fatal blood clot. Right. Micro-humans aside, imagine the inflammation that metal sub would cause.

Ideally, injectable or implantable medical devices should not only be small and electrically functional, they should be soft, like the body tissues with which they interact. Scientists from two UChicago labs set out to see if they could design a material with all three of those properties.

The material they came up with, published online June 27, 2016, in Nature Materials, forms the basis of an ingenious light-activated injectable device that could eventually be used to stimulate nerve cells and manipulate the behavior of muscles and organs.

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I like this article because I have for years looked at options to address the counterfeiting issues which is a extremely costly criminal industry around diamonds and artwork. As we have seen with synthetic diamonds in their use in QC and medical technology there is a lot that technology can do in addressing the counterfeiting issues as well as registration & certification space. Also, could registered & embedded serialized stones be another form of id for the consumer who wears their accessory with the stone? I believe it can be.


IBM launches a new high security blockchain service that uses hardware to protect valuable data, with provenance startup Everledger as its first customer.

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Columbia Engineering Professor Changxi Zheng’s new approach could lead to better tagging and coding, leveraging 3D printing of complex geometries.

New York — July 18, 2016 — Columbia Engineering researchers, working with colleagues at Disney Research and MIT, have developed a new method to control sound waves, using a computational approach to inversely design acoustic filters that can fit within an arbitrary 3D shape while achieving target sound filtering properties. Led by Computer Science Professor Changxi Zheng, the team designed acoustic voxels, small, hollow, cube-shaped chambers through which sound enters and exits, as a modular system. Like Legos, the voxels can be connected to form an infinitely adjustable, complex structure. Because of their internal chambers, they can modify the acoustic filtering property of the structure—changing their number and size or how they connect alters the acoustic result.

“In the past, people have explored computational design of specific products, like a certain type of muffler or a particular shape of trumpet,” says Zheng, whose team is presenting their paper, “Acoustic Voxels: Computational Optimization of Modular Acoustic Filters,” at SIGGRAPH 2016 on July 27. “The general approach to manipulating sound waves has been to computationally design chamber shapes. Our algorithm enables new designs of noise mufflers, hearing aids, wind instruments, and more — we can now make them in any shape we want, even a 3D-printed toy hippopotamus that sounds like a trumpet.” VIDEO: http://www.cs.columbia.edu/cg/lego/

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This will definitely make designer wear fashion very collectable and easier for investigators and consumer to detect fakes due to biometric readers. Unfortunately, Coco Chanel and Gianni Versace are not around to participate.


Designer Tina Gorjanc is using Alexander McQueen’s DNA to grow “skin” complete with freckles and tattoos that will be tanned to create jackets and bags.

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