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Category: biotech/medical

Scientists in Germany have discovered a protein that can prompt the body’s blood stem cells to act young again, potentially reversing some of the bad aspects of the aging process.

The suggestion that young blood may be the key to reversing some of the negative aspects of aging sounds like the setup to a horror movie. In reality, however, it refers to some groundbreaking work being carried out by scientists at the University of Ulm in Germany.

They’ve been examining the ways that old blood can be made young again, and they hypothesize that it might help fight some of the effects of aging. To achieve this, they’ve discovered a protein capable of boosting blood stem cells, which prompt them to act like the stem cells of younger people.

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I was under the impression that human trials were already underway, but this says they will start in 6 months.

UNSW researchers have made a discovery that could lead to a revolutionary drug that actually reverses ageing, improves DNA repair and could even help NASA get its astronauts to Mars.

In a paper published in Science today, the team identifies a critical step in the molecular process that allows cells to repair damaged DNA.

Their experiments in mice suggest a treatment is possible for DNA damage from ageing and radiation. It is so promising it has attracted the attention of NASA, which believes the treatment can help its Mars mission.

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People who received regular lifestyle counseling online were able to lower their blood pressure as much as a medication would, researchers said Saturday.

Their study involved 264 people with and an average age of 58.

The subjects’ average blood pressure began at around 140/90 mmHg, meaning they had what is clinically known as stage 1 hypertension.

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A team of researchers from Sweden, France, Belgium and Switzerland has found a way to reverse resistance to an antibiotic drug used to treat tuberculosis. In their paper published in the journal Science, the team describes how they screened compounds that activated different pathways to activate ethionaide, a compound used to treat tuberculosis.

The researchers are currently working with GlaxoSmithKline and Biotech Bioversys to further develop the small prototype molecule into a drug that can be mass produced and sold.

(Medical Xpress)—A team of researchers from Sweden, France, Belgium and Switzerland has found a way to reverse resistance to an antibiotic drug used to treat tuberculosis. In their paper published in the journal Science, the team describes how they screened compounds that activated different pathways to activate ethionaide, a compound used to treat tuberculosis.

The development of antibiotics to treat bacterial infections has very clearly made the world a healthier place. Unfortunately, over time, bacteria have been evolving to thwart such compounds, putting us all at risk once again. Because of that, scientists have been searching for new treatments, or in some cases, ways to make old treatments work again using new techniques. In this new effort, the researchers have found a way to make ethionaide, a prodrug (a compound that is metabolized in the body to produce a desired drug), become effective again in patients infected with of Mycobacterium tuberculosis.

Ethionaide was developed back in the late 1950s as a treatment for tuberculosis. It is activated by an enzyme called EthA found in the bacteria—once activated, ethionaide attacks the bacteria. Over time, many strains of M. tuberculosis have become resistant to ethionaide by developing EthA mutations that do not activate the compound, making it useless as a treatment. To get around this problem, the researchers searched for and found a prototype molecule called SMARt-420 that activates ethionaide by taking a different route—interacting with a secondary gene. The team has found that giving patients a dose of the small molecule after administering a dose of ethionaide restored the lattter’s ability to destroy a range of M. tuberculosis—testing showed it reduced the bacterial load found in patient lungs after just three weeks—similar to the effectiveness of ethionaide alone against M. prior to the develop of resistance.

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President Donald Trump has signed a bill authorizing $19.5 billion in funding for NASA, which includes an increased focus on deep space exploration and a new goal of a manned mission to Mars.

The NASA Transition Authorization Act of 2017, or S. 442, provides funding for fiscal year 2018, which begins October 1. It specifically appropriates money for NASA’s deep space exploration, including the Space Launch System and the Orion spacecraft, as well as for the ongoing medical monitoring and treatment of astronauts. It builds on the current public-private partnership for space, with commercial companies transporting American astronauts to the International Space Station (ISS) and NASA focusing on deep space and the mission to Mars.

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