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Is ageing a disease? One that can be ‘cured’? BBC’s Gabriela Torres meets the self-experimenters and scientists who are trying to dramatically extend our lives.

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An experimental treatment completely reversed Alzheimer’s disease in mice by reducing the levels of a single enzyme in the animals’ brains. The results further bolster the theory that amyloid plaques are at the root of this mysterious brain disease, and that addressing these plaques could lead to an eventual cure for Alzheimer’s. The study, published February 14 in the Journal of Experimental Medicine, found that slowly reducing levels of the enzyme BACE1 in mice as they aged either prevented or reversed the formation of amyloid plaques in the brain, a hallmark sign of Alzheimer’s disease…

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The Undoing Aging 2018 Conference is coming to Berlin to discuss the science of rejuvenation biotech!


The SENS Research Foundation and the Forever Healthy Foundation have joined forces to host an exciting conference about rejuvenation biotechnology on March 15–17, 2018 at the Umspannwerk Alexanderplatz in Berlin, Germany.

A conference for everyone

The conference is open to the wider community interested in this field and anyone can attend. We believe that this is a fantastic move, as it allows more people to engage with the science and to learn firsthand from the researchers working on the front line. We very much support the idea that we are all in this together and thus are delighted to see that the event is open to the entire community.

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Summary: Practical tips on how to consume 10 servings of fruits and vegetables daily to lose weight and improve health. [This article first appeared on the LongevityFacts website. Author: Brady Hartman.]

Fruits and vegetables are rich in phytonutrients and are an integral part of the healthiest diet plans. Here are practical tips on how to incorporate more plant foods into your meals.

Due to a poor diet, about half of all American adults have one or more preventable chronic diseases, including type 2 diabetes, overweight, obesity or cardiovascular disease. A large body of evidence, including newly published research on the health benefits of fruit and vegetables, shows that increased consumption of whole plant foods is linked to reduced risk of death and chronic diseases.

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Doctors implicate chronic inflammation as a cause of heart disease and cancer with some claiming that reducing persistent, low-grade inflammation will reduce these diseases. In fact, a recent clinical trial discovered that the inflammation-lowering drug Canakinumab reduced heart attack and strokes by nearly a fourth and cancer by about half.

More than ever, physicians believe that reducing chronic inflammation will also reduce heart attacks and strokes. Robert A. Harrington, M.D., a Cardiologist with the Department of Medicine at Stanford University, leans toward the inflammatory hypothesis of heart disease, a belief that chronic inflammation is a significant cause of heart disease. According to Dr. Harrington.

“Inflammatory cells and signals drive the healing response to vascular injury, allowing the initiation and growth of atherosclerotic plaque.”

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Summary: Lose weight with coffee? Probably not. While coffee is a healthy drink, and research suggests it helps ward off type 2 diabetes in habitual drinkers, new studies suggest that coffee probably won’t help in weight loss. [This article first appeared on the website LongevityFacts. Author: Brady Hartman. ]

People love to wake up each morning to the smell of hot coffee brewing. Coffee and the caffeine it contains are a great way to kick-start the day. About half of American adults drink coffee every day, drinking about 3 cups on average.

The beverage is consumed all over the world. Coffee originated in northeast Africa and spread throughout the Middle East in the 15th century from where it went on to Europe.

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Take Home Message

  • The EPIC Systematic Review showed that chocolate lowered the risk of coronary heart disease by 25% and cardiovascular deaths by 45%.
  • Raw cocoa powder is lower in calories when compared to chocolate.
  • Cocoa has many antioxidants called flavonols, shown to be heart healthy.
  • Research suggests that cocoa reduces atrial fibrillation, improves cholesterol, benefits vascular health and reduces blood pressure.
  • Cocoa is the key ingredient in heart healthy chocolate.
  • Dark chocolate is also heart healthy and is higher in flavonols than cocoa powder. Dark chocolate has more fat.
  • Dark chocolate and cocoa powder both have their advantages.
  • To get the heart health benefits of chocolate without the extra calories, add a pure cocoa powder to foods you normally consume.

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Summary: Nanodocs are medical nanorobots that work from inside like a tiny doctor. The authors of a recent research study say we may be able to swallow the doctor sooner than we think. Once considered science fiction, the ability to “swallow the surgeon” – using medical nanobots to diagnose and treat disease from inside the body – is becoming a reality. The study authors highlight recent advances in nanotechnology tools, such as nanodrillers, microgrippers, and microbullets – and show how nanodocs have tremendous potential in the areas of precision surgery, detection, detoxification and targeted drug delivery. [Cover photo: The old way to swallow the surgeon. Credit: R. Collin Johnson / Attributed to Stanford University.]

Imagine that you need to repair a defective heart valve, a major surgery. Instead of ripping your chest cut open, a doctor merely injects you with a syringe full of medical nanorobots, called nanodocs for short. You emerge from the ‘surgery’ unscathed, and your only external wound is the puncture hole from the injection.

According to a recent study published by nanorobotic engineers at the University of California San Diego (UCSD), the concept of ‘swallow the doctor’ may be closer to reality than we think.

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