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“There are more synapses in a human brain than there are stars in the galaxy. The brain is the most complex object we know of and understanding its connections at this level is a major step forward in unravelling its mysteries,” said lead author Dr. Seth Grant at the Center for Clinical Brain Sciences.

Imagine a map of every single star in an entire galaxy. A map so detailed that it lays out what each star looks like, what they’re made of, and how each star is connected to another through the grand physical laws of the cosmos.

While we don’t yet have such an astronomical map of the heavens, thanks to a momentous study published last week in Neuron, there is now one for the brain.

If every neuron were a galaxy, then synapses—small structures dotted along the serpentine extensions of neurons—are its stars. In a technical tour-de-force, a team from the University of Edinburgh in the UK constructed the first detailed map of every single synapse in the mouse brain.

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A new, super-insulating gel developed by researchers at CU Boulder could dramatically increase the energy efficiency of skyscrapers and other buildings, and might one day help scientists build greenhouse-like habitats for colonists on Mars.

The “aerogel,” which looks like a flattened plastic contact lens, is so resistant to heat that you could put a strip of it on your hand and a fire on top without feeling a thing. But unlike similar products on the market, the material is mostly see-through.

“Transparency is an enabling feature because you can use this gel in windows, and you could use it in extraterrestrial habitats,” said Ivan Smalyukh, a professor in the Department of Physics. “You could harvest sunlight through that thermally-insulating material and store the energy inside, protecting yourself from those big oscillations in temperature that you have on Mars or on the moon.”

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This story is brought to you by SynbiCITE, which is accelerating the commercialization of synthetic biology applications. To learn how SynbiCITE is nucleating a sustainable UK economy, visit www.synbicite.com.

Just as Henry Ford’s assembly line revolutionized the automobile industry, synthetic biology is being revolutionized by automated DNA assembly (see SynBioBetaLive! with Opentrons). The key features of an assembly line translate well into the field of synthetic biology – speed, accuracy, reproducibility and validation. Instead of welding chassis together, small robotic arms are lifting delicate plates holding dozens of samples, adding and removing miniscule amounts of fluid.

In 2014, Imperial College London received £2 million to develop a DNA Synthesis and Construction Foundry to operate with SynbiCITE, the UK Innovation and Knowledge Centre for synthetic biology. Speaking at the Foundry’s inception, SynbiCITE co-director Prof. Paul Freemont said, “Standardizing the methods for synthesising DNA is crucial if we are going to scale up efforts to design and create this genetic material. The new DNA Synthesis and Construction Foundry will streamline and automate the ‘writing’ of DNA at an industrial scale so that tens of thousands of designed DNA constructions can be built and tested.”

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Consumer DNA tests have taken off in popularity, promising to give you clues to your heritage and health. But after the test is done, who owns your personal genetic data? Bloomberg QuickTake explains why you should think twice before sending in that vial.

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A new form of electronics manufacturing which embeds silicon nanowires into flexible surfaces could lead to radical new forms of bendable electronics, scientists say.

In a new paper published today in the journal Microsystems and Nanoengineering, engineers from the University of Glasgow describe how they have for the first time been able to affordably ‘print’ high-mobility semiconductor onto flexible surfaces to develop high-performance ultra-thin electronic layers.

Those surfaces, which can be bent, flexed and twisted, could lay the foundations for a wide range of applications including video screens, improved health monitoring devices, implantable devices and synthetic skin for prosthetics.

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When skeletal defects are unable to heal on their own, bone tissue engineering (BTE), a developing field in orthopedics can combine materials science, tissue engineering and regenerative medicine to facilitate bone repair. Materials scientists aim to engineer an ideal biomaterial that can mimic natural bone with cost-effective manufacturing techniques to provide a framework that offers support and biodegrades as new bone forms. Since applications in BTE to restore large bone defects are yet to cross over from the laboratory bench to clinical practice, the field is active with burgeoning research efforts and pioneering technology.

Cost-effective three-dimensional (3D) printing (additive manufacturing) combines economical techniques to create scaffolds with bioinks. Bioengineers at the Pennsylvania State University recently developed a composite ink made of three materials to 3D print porous, -like constructs. The core materials, polycaprolactone (PCL) and poly (D, L-lactic-co-glycolide) acid (PLGA), are two of the most commonly used synthetic, biocompatible biomaterials in BTE. Now published in the Journal of Materials Research, the materials showed biologically favorable interactions in the laboratory, followed by positive outcomes of in an animal model in vivo.

Since bone is a complex structure, Moncal et al. developed a bioink made of biocompatible PCL, PLGA and hydroxyapatite (HAps) particles, combining the properties of bone-like mechanical strength, biodegradation and guided reparative growth (osteoconduction) for assisted natural bone repair. They then engineered a new custom-designed mechanical extrusion system, which was mounted on the Multi-Arm Bioprinter (MABP), previously developed by the same group, to manufacture the 3D constructs.

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Aging is a battle that humans have known they can’t win since the beginning of history. We can hate it or (eventually) accept it but ultimately we can’t avoid growing old. However, over the years scientists have been trying to pinpoint the roots of this biological process and work out if there is any way to stop or reverse it. There have been some minor successes along the way and a new study adds to these.

The researchers were able to reverse the aging process of some old human cells by delivering a specific molecule to their mitochondria, the structures within cells where energy is produced. This approach stops the cells from becoming senescent, a point at which they can no longer duplicate. Some researchers believe that the accumulation of these cells in organs is key to the aging process.

“We still don’t fully understand why cells become senescent as we age, but damage to DNA, exposure to inflammation and damage to the protective molecules at the end of the chromosomes – the telomeres – have all been suggested,” the authors wrote in a post on The Conversation. “More recently, people have suggested that one driver of senescence may be loss of our ability to turn genes on and off at the right time and in the right place.”

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Shares in German chemicals and pharmaceuticals giant Bayer tumbled more than 10 percent as markets opened Monday, as investors reacted to a shock US ruling against freshly-acquired Monsanto.

Stock in the Leverkusen-based group fell 10.4 percent to 83.61 euros ($95.19) around 9:25 am (0725 GMT), after a California jury on Friday awarded a dying groundskeeper damages of almost $290 million, saying Monsanto should have warned buyers that its flagship Roundup weedkiller could cause cancer.

While observers have predicted thousands of other claims could follow, Bayer said the jury’s findings went against scientific evidence and that other courts might “arrive at different conclusions”.

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